Displaying publications 1 - 20 of 59 in total

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  1. Anwar A, Khan NA, Alharbi AM, Alhazmi A, Siddiqui R
    Int Ophthalmol, 2024 Mar 15;44(1):140.
    PMID: 38491335 DOI: 10.1007/s10792-024-03062-4
    Keratitis is corneal inflammatory disease which may be caused by several reason such as an injury, allergy, as well as a microbial infection. Besides these, overexposure to ultraviolet light and unhygienic practice of contact lenses are also associated with keratitis. Based on the cause of keratitis, different lines of treatments are recommended. Photodynamic therapy is a promising approach that utilizes light activated compounds to instigate either killing or healing mechanism to treat various diseases including both communicable and non-communicable diseases. This review focuses on clinically-important patent applications and the recent literature for the use of photodynamic therapy against keratitis.
    Matched MeSH terms: Contact Lenses*
  2. Ahmad A, Mohd-Ali B, Ishak B
    Clin Optom (Auckl), 2018;10:109-113.
    PMID: 30319302 DOI: 10.2147/OPTO.S172272
    Purpose: Soft contact lens wear is most frequently associated with morphologic changes in corneal endothelial cells, but the data are scarce in Asians. This study aimed to evaluate changes in corneal endothelial cell morphology after 6 months of wearing soft hydrogel contact lenses (SH) in young myopic adults living in Kuala Lumpur.

    Patients and methods: Forty-eight subjects were included in the study, 24 were fitted with SH contact lenses (A) and the rest were prescribed with glasses (B). Refraction was conducted subjectively and standard contact lens fitting protocol was followed. Corneal endothelial cell morphology (endothelial cell density, ECD; coefficient of variation, COV; cells' hexagonality, HEX; and central corneal thickness, CCT) was evaluated using specular microscope. Data were collected at baseline and after 6 months of lens wear.

    Results: Mean age of all subjects was 21.23±1.30 years. All results are shown at baseline and 6 months, respectively. Mean refraction for A was -2.16±0.97 diopter sphere (DS) and -2.05±1.03 DS (P=0.49); for B was -2.72±1.51 DS and -2.73±1.51 DS (P=0.58). Mean ECD (cell/mm2) for A: 3104.19±237.30 and 3107.23±237.51 (P=0.07); for B: 3011.56±227.95 and 2983.83±244.55 (P=0.33). COV (%) for A: 46.52±8.63 and 48.53±10.65 (P=0.06); for B: 46.93±9.31 and 46.14±10.65 (P=0.88). HEX (%) for A: 46.21±10.12 and 45.15±10.01 (P=0.08); for B: 46.21±10.12 and 45.15±10.01 (P=0.12). CCT (µm) for A: 520.33±0.04 and 525.70±0.05 (P=0.41); for B: 532.00±0.04 µm and 530.00±0.05 µm (P=0.40).

    Conclusion: This study found no significant change in corneal endothelial cell morphology after 6 months of wearing SH contact lenses. This is probably due to better oxygen permeability of the contact lens material, good compliance, and short wearing period.
    Matched MeSH terms: Contact Lenses*
  3. Thite N, Desiato A, Shinde L, Wolffsohn JS, Naroo SA, Santodomingo-Rubido J, et al.
    Cont Lens Anterior Eye, 2021 12;44(6):101496.
    PMID: 34426063 DOI: 10.1016/j.clae.2021.101496
    AIM: To understand the views of contact lens (CL) practitioners across the globe regarding what they perceive as opportunities and threats in CL practice.

    METHODS: A self-administered anonymised questionnaire, constructed in English and translated in six more languages, was distributed through reputed international professional bodies and academic institutions worldwide. The questionnaire included items on demographic characteristics, type of practice, and questions designed to explore practitioners' perspective on the future of their CL practice over the next five years.

    RESULTS: A total of 2408 valid responses were analysed. Multifocal CLs for presbyopia, CLs for myopia control, use of daily disposable (DD) CLs for occasional wear, and biocompatible materials to improve comfort were identified as promising areas of opportunities by practitioners (all 8/10). Respondents from North America, and Europe valued DDCLs for occasional wear moderately more favourable (Median: 9/10 for all) as compared to colleagues in Asia (Median: 8/10, p 

    Matched MeSH terms: Contact Lenses*
  4. Mohd-Ali B, Low YC, Mohamad Shahimin M, Arif N, Abdul-Hamid H, Wan Abdul-Halim WH, et al.
    Cont Lens Anterior Eye, 2023 Feb;46(1):101774.
    PMID: 36319519 DOI: 10.1016/j.clae.2022.101774
    PURPOSE: There are limited reports available on the impact of wearing Orthokeratology (ortho-K) lenses on the quality of life of Asian children. This study evaluated and compared vision-related quality of life (VRQoL) between myopic children wearing ortho-K lenses and single-vision spectacles (SVSs), living in Kuala Lumpur, using Paediatric Refractive Error Profile (PREP) questionnaires.

    METHODS: This is a cross sectional study. Myopic children who had been wearing ortho-K and SVSs for 12 months were recruited, and the questionnaires were distributed online. The PREP scores were obtained using a summary scoring method. The Shapiro-Wilk test was used to determine data normality. Unpaired t-test was performed for normally distributed data, and the Mann-Whitney test for non-normally distributed data. P 

    Matched MeSH terms: Contact Lenses*
  5. Chuprom J, Sangkanu S, Mitsuwan W, Boonhok R, Mahabusarakam W, Singh LR, et al.
    PeerJ, 2022;10:e14468.
    PMID: 36523474 DOI: 10.7717/peerj.14468
    Garcinia mangostana L., also known as the mangosteen tree, is a native medicinal plant in Southeast Asia having a wide variety of pharmacologically active compounds, including xanthonoid mangostin. In this study, we examined the pharmacological activities of the selected semi-synthetic mangostin derivative, namely, amoebicidal activity, encystation inhibition, excystation activity, and removal capacity of adhesive Acanthamoeba from the surface of contact lens (CL). Among the three derivatives, C1 exhibited promising anti-Acanthamoeba activity against Acanthamoeba triangularis WU19001 trophozoites and cysts. SEM images displayed morphological changes in Acanthamoeba trophozoites, including the loss of acanthopodia, pore formation in the cell membrane, and membrane damage. In addition, the treated cyst was shrunken and adopted an irregular flat cyst shape. Under a fluorescence microscope, acridine orange and propidium iodide (AO/PI) staining revealed C1 induced condensation of cytoplasm and chromatin with the loss of cell volume in the treated trophozoites, while calcofluor white staining demonstrated the leakage of cell wall in treated cysts, leading to cell death. Interestingly, at the concentration ranges in which C1 showed the anti-Acanthamoeba effects (IC50 values ranging from 0.035-0.056 mg/mL), they were not toxic to Vero cells. C1 displayed the highest inhibitory effect on A. triangularis encystation at 1/16×MIC value (0.004 mg/mL). While C1 demonstrated the excystation activity at 1/128×MIC value with a high rate of 89.47%. Furthermore, C1 exhibited the removal capacity of adhesive Acanthamoeba from the surface of CL comparable with commercial multipurpose solutions (MPSs). Based on the results obtained, C1 may be a promising lead agent to develop a therapeutic for the treatment of Acanthamoeba infections and disinfectant solutions for CL.
    Matched MeSH terms: Contact Lenses*
  6. Allinjawi K, Sharanjeet-Kaur SK, Akhir SM, Mutalib HA
    F1000Res, 2016;5:2742.
    PMID: 28163898 DOI: 10.12688/f1000research.9971.1
    Aim: The purpose of this study was to compare the changes in relative peripheral refractive error produced by two different designs of progressive soft contact lenses in myopic schoolchildren. Methods: Twenty-seven myopic schoolchildren age between 13 to 15 years were included in this study. The measurements of central and peripheral refraction were made using a Grand-Seiko WR-5100K open-field autorefractometer without correction (baseline), and two different designs of progressive contact lenses (PCLs) (Multistage from SEED & Proclear from Cooper Vision) with an addition power of +1.50 D. Refractive power was measured at center and at eccentricities between 35º temporal to 35º nasal visual field (in 5º steps). Results: Both PCLs showed a reduction in hyperopic defocus at periphery. However, this reduction was only significant for the Multistage PCL (p= 0.015), (Proclear PCL p= 0.830).  Conclusion: Multistage PCLs showed greater reduction in peripheral retinal hyperopic defocus among myopic schoolchildren in comparison to Proclear PCLs.
    Matched MeSH terms: Contact Lenses, Hydrophilic
  7. Md. Muziman Syah, M.M., Mutalib, H. A., Sharanjeet Kaur, M. S., Khairidzan, M. K.
    MyJurnal
    Introduction: The purpose of this study was to derive a modified equation for contact lens method (CLM) in
    calculating post myopic laser refractive surgery corneal power. Methods: A total of 93 subjects who
    underwent myopic laser refractive surgery at IIUM Eye Specialist Clinic were recruited. The accuracy of
    postoperative corneal power using the standard CLM and newly-derived contact lens modified method
    (CLMmod) were compared to the standard comparison method ; the historical method (HM). The CLMmod
    equation was derived by adjusting postoperative corneal power of CLM according to amount of refractive
    change. Results: The mean postoperative corneal power using standard CLM was significantly higher than
    HM (mean difference: -0.24 D, p < 0.001). Fifty seven percent (n = 53 eyes) of the standard CLM results were
    within ±0.50 D of HM results. The difference between postoperative corneal power using standard CLM and
    HM increased significantly with the amount of refractive change (r = 0.835; p < 0.001). The mean
    postoperative corneal power of CLMmod showed that there was no statistical significant difference compared
    to the HM results (mean difference: 0.00 D, p= 0.964). Eighty eight percent (n = 82 eyes) of the CLMmod
    results were within ±0.50 D of HM results with improvement of 31% from the standard CLM results.
    Conclusion: The CLMmod equation provides more accurate calculation in determining post myopic laser
    refractive surgery corneal power. In near future, this modified equation can be used as an alternative
    equation to calculate postoperative corneal power when the preoperative data is unavailable.
    Matched MeSH terms: Contact Lenses
  8. Bhandari M, Hung PR
    Med J Malaysia, 2012 Jun;67(3):274-7.
    PMID: 23082416 MyJurnal
    The purpose to do this research was to find out the habits of contact lens wearers towards lens care in this country, and to evaluate the compliance of contact lens wearers.
    METHODS: All respondents underwent an interview regarding questionnaire which was carried out at the Klang Valley and Sabah, Malaysia by trained bilingual optometrists. The questionnaire was obtained from a study by Yvonne Wu et al., 2010. The questionnaire included information about respondents' demographics, contact lens hygiene behaviors and attitudes toward lens care. Comparison between groups and certain factors of lens care were analyzed.
    RESULTS: Within the 100 respondents, 74% were female. The majority used monthly disposable lens (53%, 53/100), 35% (35/100) wore daily lens, 3% (3/100) wore biweekly disposable lens, 8% (8/100) wore quarter-yearly (3 months) lens, and only a participant (1%) used conventional lenses. The major non-compliance aspect that found out from this research were poor lens case (46%), inadequate cleaning of lens before storing (38%) and wearers not remembering how often they were advised to return for an aftercare (24%).
    CONCLUSION: The poor lens care hygiene, inadequate cleaning of lens before storing may due to lack of proper advice to the contact lens wearers during examination or lack of awareness of aftercare visit.
    Matched MeSH terms: Contact Lenses*
  9. Mutilab HA, Sharanjeet-Kaur, Keu LK, Choo PF
    Clin Ter, 2012;163(3):199-204.
    PMID: 22964691
    PURPOSE: The objective of this study was to determine the visual function of colour-deficient subjects when wearing special red tint contact lenses.
    MATERIALS AND METHODS: A total of 17 subjects with congenital colour vision deficiency (14 deutans and 3 protans), voluntarily participated in this study. The average age for the subjects was 23.00 ± 4.06 years old. Visual functions tested were visual acuity (LogMAR), contrast sensitivity (FACT Chart) and stereopsis (TNO and Howard Dolman tests). Two types of special red tint lenses were used in this study; Type I (light red) and Type II (dark red).
    RESULTS: The protans and deutans showed no significant changes in visual acuity and contrast sensitivity when wearing either type of contact lens. Stereopsis testing using the Horward-Dolman test gave no significant changes but significant differences were seen using the TNO test. Stereopsis using the TNO test was significantly poorer with the red tinted contact lenses compared to without for both protons and deutans. Testing binocularly with Ishihara plates showed that 88% (n=15) of patients passed the test with Type I and Type II contact lenses. When D15 test was done, 3 patients (17.6%) were 'normal' when using the Type I contact lenses and 2 patients (11.8%) were 'normal' when using the Type II contact lenses. However, with FM100Hue test, most patients showed deutan responses. Total error scores (TES) were found to be higher with Type I and Type II contact lenses compared to without.
    CONCLUSIONS: The Type I and II special tinted contact lens used in this study did not cause a reduction of visual acuity and contrast sensitivity for the colour defects. Stereopsis was also not reduced with the Type I and Type II contact lenses for the colour defects except when tested with the TNO test. Colour vision defects became difficult to detect using the Ishihara plates but FM100Hue test did not show any improvement with the Type I and Type II contact lenses.
    Matched MeSH terms: Contact Lenses*
  10. Cheah PS, Norhani M, Bariah MA, Myint M, Lye MS, Azian AL
    Cornea, 2008 May;27(4):461-70.
    PMID: 18434851 DOI: 10.1097/ICO.0b013e318165642c
    To investigate the histological changes in primate cornea induced by short-term overnight orthokeratology (OK).
    Matched MeSH terms: Contact Lenses*
  11. Kamel AG, Norazah A
    Trans R Soc Trop Med Hyg, 1995 11 1;89(6):652.
    PMID: 8594684
    Matched MeSH terms: Contact Lenses/adverse effects*
  12. Bhandari M, Wei Ern RL, Majumder C, Ho D
    Med J Malaysia, 2019 02;74(1):30-33.
    PMID: 30846659
    PURPOSE: To determine the effects of ChromaGen blue filter lens in reading speed, accuracy and contrast sensitivity.

    METHODS: A cross-over, randomised study was carried out on 40 individuals (11 males and 29 females) aged 21 to 30 years. The rate of reading and reading accuracy was calculated with and without ChromaGen blue filter lens in all subjects. Wilkins Rate of Reading Test was used to measure the rate of reading and reading accuracy. Contrast sensitivity was also evaluated by using with and without the ChromaGen blue filter lens.

    RESULTS: The mean rate of reading with and without ChromaGen blue filter lens was 160.58±16.03 words per minute and 150.52±15.66 words per minute respectively, with significant difference of p<0.001. The mean of reading accuracy (words correctly read per minute) in subjects, with ChromaGen blue filter was 149.30±0.79 words and without using filter lens was 148.53±1.11 words and found to be significant (p<0.001). There was no significant difference in the contrast sensitivity between subjects with and without the ChromaGen blue filter lens (p=0.083). No significant correlation was noted between the reading speed with age, spherical equivalent, contrast sensitivity, and reading accuracy.

    CONCLUSION: This study concludes that there was an increase of 6.68% in the rate of reading and improvement of 0.52% in accuracy among subjects with ChromaGen blue filter lens.

    Matched MeSH terms: Contact Lenses*
  13. Mohd-Ali B, Tan XL
    PMID: 31861174 DOI: 10.3390/ijerph16245161
    BACKGROUND: Contact lenses (CLs) are more popular than spectacles for vision correction amongst the youth. Knowledge about the risks of wearing CLs is critical especially for those with poor access to public health education. This study investigates the patterns of use and level of knowledge about CL wear amongst teenagers living in rural areas in Selangor, Malaysia using a set of validated questionnaires.

    METHODS: A total of 8500 self-administered questionnaires were distributed in eight selected secondary schools. The results were analysed using descriptive statistics.

    RESULTS: A total of 2474 (29%) completed questionnaires were collected. The mean age of the respondents was 14.8 ± 1.5 years, and approximately 7.2% were CL wearers. The majority of the wearers were females (76.0%) and wore soft CLs (92.2%). Cosmetic purposes (58.1%) and comfort (24.6%) were the main reasons for wearing CLs. Many of the respondents purchased their lenses from optical shops (50.1%) and beauty accessory shops (15.6%), and approximately 10% did not disinfect their lenses properly. Regarding knowledge about CL care, approximately 56% of the respondents responded correctly.

    CONCLUSION: Half of the respondents do not have sufficient knowledge about the risks of wearing CLs. Thus, aggressive public health education aimed at teenagers is needed to prevent improper CL usage.

    Matched MeSH terms: Contact Lenses*
  14. Tong WY, Tan WN, Kamarul Azizi MA, Leong CR, El Azab IH, Lim JW, et al.
    Chemosphere, 2023 Oct;338:139492.
    PMID: 37451643 DOI: 10.1016/j.chemosphere.2023.139492
    Vancomycin is the last resort antibiotic for the treatment of severe bacterial keratitis. Its clinical application is limited due to its hydrophilicity and high molecular weight. To overcome this, this study aims to develop nanoparticles-laden contact lens for controlled ocular delivery of vancomycin. Polyvinyl alcohol (PVA) was used as encapsulant material. The nanoparticles had a negative surface charge and an average size of 147.6 nm. A satisfactory encapsulation efficiency (61.24%) was obtained. The release profile was observed to be slow and sustained, with a release rate of 1.29 μL mg-1 h-1 for 48 h. Five out of 6 test bacteria were suppressed by vancomycin nanoparticles-laden contact lens. Vancomycin is generally ineffective against Gram-negative bacteria and unable to pass through the outer membrane barrier. In this study, vancomycin inhibited Proteus mirabilis and Pseudomonas aeruginosa. Nano-encapsulation enables vancomycin to penetrate the Gram-negative cell wall and further destroy the bacterial cells. On Hohenstein challenge test, all test bacteria exhibited significant reduction in growth when exposed to vancomycin nanoparticles-laden contact lens. This study created an effective and long-lasting vancomycin delivery system via silicone hydrogel contact lenses, by using PVA as encapsulant. The antibiotic efficacy and vancomycin release should be further studied using ocular in vivo models.
    Matched MeSH terms: Contact Lenses*
  15. Allinjawi K, Kaur S, Akhir SM, Mutalib HA
    Saudi J Ophthalmol, 2020 12 28;34(2):94-100.
    PMID: 33575529 DOI: 10.4103/1319-4534.305035
    PURPOSE: The purpose was to determine the minimum near-addition power needed using Proclear® multifocal D-Design contact lens (adds: +1.50 D, +2.50 D, +3.00 D, and +3.50 D) to invert the pattern of relative hyperopic defocus in the peripheral retina into relative myopic defocus among the eyes of myopic schoolchildren.

    METHODS: Twenty-seven right eyes (24 females and 3 males) of 27 myopic schoolchildren aged between 13 and 15 years were included in this study. The measurements of central refraction, peripheral refraction (between 35° temporal and 35° nasal visual field in 5° steps), and lag of accommodation were conducted using the Grand-Seiko WR-5100K open-field autorefractometer initially without correction (WC), followed by with correction using four different addition powers of Proclear® multifocal D-Design contact lens in random sequence. Axial length was measured using a handheld probe ultrasound A-scan (Tomey AL-2000).

    RESULTS: The relative peripheral refractive error showed high hyperopic defocus of +1.08 ± 1.24 D at 35° nasal and +1.06 ± 1.06 D at 35° temporal visual field WC. All Proclear multifocal contact lenses (MFCLs) decreased the peripheral hyperopic defocus with increasing addition powers (F [2.938, 47.001] = 13.317, P < 0.001). However, only +3.00 D addition and +3.50 D addition (P = 0.001) could invert the peripheral hyperopic defocus into peripheral myopic defocus. Apart from that, the +3.00 D addition lens showed the lowest lag of accommodation (+1.10 ± 0.83 D) among the other MFCL adds (P = 0.002).

    CONCLUSION: A +3.00 D addition Proclear MFCL is the optimal addition power that can invert the pattern of peripheral hyperopic defocus into myopic defocus.

    Matched MeSH terms: Contact Lenses
  16. Bariah Mohd Ali, Goh, E.H.
    MyJurnal
    The objective of this study was to determine the efficiency of UV blocking monomers in contact lenses in providing eye protection from UV radiation. The spectral transmission of 8 contact lenses (7 soft contact lenses: Precision UV, Acuvue 2, Surevue, Omega, Encore UV, Durasoft 3 and Lunelle UV and 1 rigid gas permeable contact lens: Boston 7) was evaluated by using a dual beam spectrophotometer. Durasoft 3, a non UV absorbent contact lens was used as the control. The results showed that Precision UV contact lens absorbed UV light up to wavelength of 380 nm, whereas Acuvue 2 and Surevue absorbed up to 360 nm only. Omega, Encore UV and Lunelle UV lenses absorbed UV light up to 335 nm with spectral transmission of Lunelle UV being the highest among all soft contact lenses tested, which was 17%. Boston 7 could absorb UV light up to 385 nm, but the amount of UV light transmitted was higher than soft lenses, which was 30%. Durasoft 3 only blocked UV light at 200-245 nm. Precision UV lens had better UV blocker characteristics than the other contact lenses tested. UV blocking soft contact lenses could be an alternative for spectacles in protecting internal ocular structures from UV radiation.
    Matched MeSH terms: Contact Lenses, Hydrophilic
  17. Norhani Mohidin, Yap MK, Jacobs RJ
    Sains Malaysiana, 2014;43:1089-1094.
    The purpose of this study was to compare the performance of four different electrode types in detecting the multifocal electroretinogram (mfERG) using the visual evoked response imaging system (VERIS). Multifocal ERG of 30 healthy subjects aged 17-50 years was recorded. Four different types of electrodes were used (JET contact lens, gold foil, DTL thread and c-glide carbon fiber electrodes) and the trough to peak amplitude response densities of the first order kernels (which approximated to the a and b wave of the full field electroretinogram) were compared. The JET contact lens electrode produced the highest amplitude response which was significantly different from the gold foil, DTL thread and the c-glide electrodes, but there was no significant difference between the gold foil and DTL or between DTL and the c-glide electrodes. In conclusion, contact lens electrode produced the highest response density followed by the gold foil and the DTL thread. There was no significant difference in amplitude response between the gold foil and DTL thread, therefore these two electrodes provide for viable alternatives for recording mfERG especially when there are concerns that contact lens electrode may be uncomfortable for recording periods that may take a long time.
    Matched MeSH terms: Contact Lenses
  18. Lili Asma Ismail, Lekhraj Rampal, Hejar Abdul Rahman, Nazri Omar, Habshah Midi, Azrin Esmady Ariffin
    MyJurnal
    Microbial keratitis is one of the most challenging complications of contact lens (CL) wear. Proper CL practice plays an important role to reduce the risk for contact lens related microbial keratitis (CLRMK). Methods: This multi-centre case-control study was conducted from January 2008 until June 2009 to determine the risk factors associated with CLRMK. Cases were defined as respondents who were treated for CLRMK, whilst controls were respondents who were contact lens wearers without microbial keratitis. Ninety four cases were compared to 94 controls to determine the risk factors for
    CLRMK. Results: The predictors for CLRMK were: Not washing hands with soap before handling CL (aOR 2.979, CI 1.020, 8.701 p=0.046), not performing rubbing technique whilst cleaning the CL (aOR 3.006, CI 1.198, 7.538 p=0.019) and, not cleaning the lens case with multipurpose solution daily (aOR 3.242 CI 1.463, 7.186 p=0.004). Sleeping overnight with the CL in the eye (aOR 2.864, CI 0.978, 8.386 p=0.049) and overall non-compliance with lens care procedures (aOR 2.590, CI 1.003, 6.689 p=0.049) contributed significantly to CLRMK. Conclusion: Health education and promotion in contact lens care are important and should be conducted by eye care practitioners to reduce the occurrence of CLRMK.
    Matched MeSH terms: Contact Lenses
  19. Noradilah Samseh Abdullah, Mohamed Kamel Abd Ghani, Anisah Nordin, Yusof Suboh, Noraina Ab Rahim
    MyJurnal
    Acanthamoeba keratitis is a serious ocular problem and can cause blindness if not treated. This study was therefore performed to evaluate the effectiveness of eyedrop antibiotics on eight Acanthamoeba spp. isolates, of which four
    were clinical isolates and the remaining four from the environment. Three different eyedrop antibiotics (neomycin, ciprofloxacin and gentamicin) currently available in the market and ready for use were tested. Cyst suspension from all strains were tested against eyedrop antibiotics, respectively. After 48 hours of incubation period, the solutions were filtered and the filtered membranes were put onto non-nutrient agar lawn with E. coli. The plates were examined daily for Acanthamoeba trophozoites under inverted microscope until day 14. Neomycin, ciprofloxacin and gentamicin were found
    to be effective against Acanthamoeba spp. cysts for all test strains.
    Key words: Acanthamoeba Keratitis, Eyedrop Antibiotics, Effectiveness
    Matched MeSH terms: Contact Lenses
  20. Syazwan Hafiz Mohd, Wan Elhami Wan Omar, Ai-Hong Chen
    MyJurnal
    This paper examines the chemical elements used as colour additives in cosmetic coloured contact lenses (Cos-CCL) using Field Emission Scanning Electron Microscope equipped with Energy Dispersive X-ray Spectroscopy (FESEM-EDX) analysis. The samples comprised two different Cos-CCL brands and colours (sample A1-black iris colour & B1-gray iris colour) with their respective clear contact lens counterparts as controls (sample A2 & B2). The parameters of Cos-CCL were observed carefully so that they resembled their respective controls. All the samples were analysed for chemical element characterisation by using EDX spectroscopy surface mapping analysis on both front and back surfaces. EDX spectroscopy point analysis was done on cross-section surface of Cos-CCL when colour additive pattern could not be detected by FESEM on either surface. FESEM-EDX spectroscopy analysis has revealed iron element in the colour additives of the A1 sample and aluminium elements in the B2 sample. These two elements were not present in the respective control samples. It can be concluded that iron and aluminium elements are exclusively attributed to the colour additive in Cos-CCL samples. It is important for manufacturers of Cos-CCL to disclose information of their products and create greater awareness on the risks facing users.
    Matched MeSH terms: Contact Lenses
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