Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting

Zakaria MS 1 , Ismail F 2 , Tamagawa M 3 , Aziz AFA 4 , Wiriadidjaja S 1 , Basri AA 1 Show all authors , Ahmad KA 5

Affiliations 

  • 1 Department of Aerospace Engineering, Faculty of Engineering, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia
  • 2 School of Aerospace Engineering, Universiti Sains Malaysia, George Town, Malaysia
  • 3 Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Kitakyushu, Japan
  • 4 Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Serdang, Malaysia
  • 5 Department of Aerospace Engineering, Faculty of Engineering, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia. [email protected]
Med Biol Eng Comput, 2017 Sep;55(9):1519-1548.
PMID: 28744828 DOI: 10.1007/s11517-017-1688-9

Abstract

Even though the mechanical heart valve (MHV) has been used routinely in clinical practice for over 60 years, the occurrence of serious complications such as blood clotting remains to be elucidated. This paper reviews the progress that has been made over the years in terms of numerical simulation method and the contribution of abnormal flow toward blood clotting from MHVs in the aortic position. It is believed that this review would likely be of interest to some readers in various disciplines, such as engineers, scientists, mathematicians and surgeons, to understand the phenomenon of blood clotting in MHVs through computational fluid dynamics.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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