Responses were recorded from normal healthy subjects and age-related macular degeneration (AMD) patients and evaluated, using a new variant of mfVEP. Subjects information was recorded using 64 EEG channels with a computer-based acquisition system. The stimulus layout was a 84 region corticallyscaled dartboard comprising 12 sectors and seven concentric rings subtending a diameter of 23º, presented dichoptically at 60 Hz. Data from the control and AMD patients were statistically compared when fitted concurrently into the multiple regression analysis. The Pattern-pulse mfVEP technique could distinguish between normal eyes and those with a definite diagnosis of dry and wet AMD when responses from the macula were considered.