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Progesterone Receptor (PGR) gene polymorphism is associated with susceptibility to preterm birth

Langmia IM 1 , Apalasamy YD 2 , Omar SZ 3 , Mohamed Z 4

Affiliations 

  • 1 Department of Pharmacology, Pharmacogenomics Laboratory, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. [email protected]
  • 2 Department of Pharmacology, Pharmacogenomics Laboratory, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. [email protected]
  • 3 Department of Obstetrics and Gynecology, University of Malaya, 50603, Kuala Lumpur, Malaysia. [email protected]
  • 4 Department of Pharmacology, Pharmacogenomics Laboratory, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. [email protected]
BMC Med Genet, 2015;16:63.
PMID: 26286601 DOI: 10.1186/s12881-015-0202-1

Abstract

Preterm birth (PTB) is the major cause of death in newborn and the second major cause of death in children less than 5 years old worldwide. Genetic polymorphism has been implicated as a factor for the occurrence of preterm birth. The aim of this study is to evaluate whether polymorphism in the progesterone receptor (PGR) is associated with susceptibility to preterm birth.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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