Displaying publications 1 - 20 of 39 in total

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  1. Masaany BM, Ida Sadja'ah S, Norleza AN, Norzi BG, Siti Sabzah MH
    Med J Malaysia, 2012 Oct;67(5):530-1.
    PMID: 23770875 MyJurnal
    Teratomas arising from the palate or pharynx may cause immediate life-threatening airway obstruction to the newborn. Early diagnosis via antenatal ultrasound enables the treating team to perform an ex utero intrapartum treatment (EXIT) procedure to secure an airway and perform subsequent tumour resection. We present the first EXIT procedure done in Malaysia. A 34 year old , gravida 4, para 3, her unborn child diagnosed at 24 weeks of gestation to have a large oropharyngeal mass. Upper airway obstruction was anticipated. Orchestration of multiple specialities was executed to properly plan and perform the EXIT procedure. The fetus was delivered at 33 weeks of gestation and managed to be intubated. The extraoral portion of the multilobular mass originating from the palate was resected. Complete resection of the intraoral teratoma was successfully done at day 22 of life.
    Matched MeSH terms: Teratoma*
  2. Razman J, Azlanudin A, Eyad AJ, Zahiah M, Das S
    Clin Ter, 2012 Nov;163(6):495-7.
    PMID: 23306744
    Mature cystic teratomas of the pancreas are extremely rare tumours encountered in day-to-day clinical practice. Only few cases have been reported to date involving all age groups. The management, diagnosis and evaluation of this tumor are questionable, with definitive diagnosis taking place intra-operatively. We hereby report the case in a 30 year-old-male who presented with newly diagnosed diabetes mellitus and during the follow up he was noted to have elevated liver enzymes clinically, he was asymptomatic. The computerized tomography revealed a retropancreatic mass and pushing the mesenteric veins anteriorly. The mass was hypodense in nature and there was presence of calcification. Although the patient was asymptomatic, the decision for resecting the mass was made in view of the size and possibility of malignancy. In conclusion, considering the size and approximity of the mass to the pancreas, Whipple procedure's is the most appropriate approach although the histological diagnosis has not been established preoperatively.
    Matched MeSH terms: Teratoma/pathology*; Teratoma/surgery
  3. Hassan S, Sidek DS, Shah Jihan WD, Phutane G, Mutum SS
    Singapore Med J, 2007 Aug;48(8):e212-4.
    PMID: 17657368
    Teratoma of the tongue is a rare entity. We present a male newborn with massive lingual teratoma and cleft palate, which surprisingly did not cause immediate airway obstruction. This case illustrates a huge mass in the oral cavity, which was missed on antenatal ultrasonography because it did not present with polyhydramnios. The mass was excised under general anaesthesia. Histopathologically, it consisted of all three layers of embryonic elements with predominantly glial tissue. Postoperatively, the patient developed hypoglossal nerve palsy, and no recurrence was detected after four years.
    Matched MeSH terms: Teratoma/pathology*; Teratoma/surgery
  4. Kampan N, Irianta T, Djuana A, Pei Shan L, Hashim Omar M, Hatta Mohd Dali AZ
    Case Rep Obstet Gynecol, 2012;2012:134032.
    PMID: 22645693 DOI: 10.1155/2012/134032
    Growing teratoma syndrome is rare and usually it occurs in the younger aged group. The use of chemotherapy following initial surgical resection will yield the diagnosis following tumour enlargement. Complete resection is usually curative and renders better prognosis.
    Matched MeSH terms: Teratoma
  5. Mohd Bahari HM, Haron A
    Med J Malaysia, 1979 Mar;33(3):226-9.
    PMID: 522727
    Matched MeSH terms: Teratoma/diagnosis*
  6. Sreetharan SS, Prepageran N
    Med J Malaysia, 2004 Dec;59(5):678-9.
    PMID: 15889573
    A teratoma is a true neoplasm composed of an assortment of tissue often alien to the site from it arises. Teratomas of the head and neck are exceedingly rare and usually present in the neonatal period. Most of these are found in the cervical region and nasopharynx. Though most tumors are benign, they are often malignant with regards to the location. Here we present a rare case of benign teratoma arising from the nasal septum and presenting for the first time in a young adult. Appropriate literature is reviewed.
    Matched MeSH terms: Teratoma/pathology*; Teratoma/surgery
  7. De Los Reyes EVA, Rivera DI, Santos HM, Carlos RM
    Malays J Pathol, 2018 Aug;40(2):175-183.
    PMID: 30173236
    INTRODUCTION: Intracranial teratomas account for 0.5% of all intracranial tumours and 2-4% of intracranial tumours in children. However, in terms of tumours of the pineal area, the exact incidence is not ascertained. Although, it is noted that 50-60% of central nervous system (CNS) germ cell tumours are found in the pineal gland. The degree of difficulty in the sampling of lesions in the pineal gland during biopsy emphasizes the importance of correlating the imaging studies, histopathologic findings, and serum and cerebrospinal fluid (CSF) tumour markers.

    CASE REPORT: This case report is that of a 9-year-old male who presented with frontal headache of eight days, with associated photophobia, nausea and vomiting, and diplopia. Biopsy with intraoperative navigation was done and the specimen was referred for histopathologic evaluation. The biopsy showed findings consistent with a mature teratoma with no histologic findings of an immature component or secondary somatic malignancy. Comparison of the pre-operative and post-operative multiaxial cranial CT scan showed findings that was consistent with a residual lesion. This was correlated with the pre-operative serum tumour markers which showed alpha-fetoprotein of 22.5 ng/mL and beta-HCG of 1.0 mIU/mL(IU/L), and the post-operative tumour markers of the cerebrospinal fluid that showed alpha-fetoprotein of 3.28 ng/mL and beta-HCG of 18.9 mIU/mL (IU/L).

    CONCLUSION: A review of the literature and comparison with current case in relation to the histopathologic, serum and CSF findings, and imaging studies was done to better understand the mechanism of this lesion.

    Matched MeSH terms: Teratoma/diagnosis*; Teratoma/pathology*
  8. Rahman MT, Jaafar H, Naik VR, Ghazali MZ, Hassan S
    Singapore Med J, 2004 Mar;45(3):130-1.
    PMID: 15029417
    The unusual presentation of a mature mediastinal cystic teratoma as an anterior neck swelling in a 29-year-old Malay woman is reported.
    Matched MeSH terms: Teratoma/pathology*; Teratoma/surgery
  9. Harun MH, Yaacob I
    Singapore Med J, 1993 Dec;34(6):567-8.
    PMID: 8153729
    Almost all mediastinal teratomas are found in the anterior mediastinum. We describe a case of a 41-day-old baby girl who had teratoma in the posterior mediastinum. She presented at the age of 6 days with the problem of progressive jaundice and was found to have septicaemia. During septic screening, chest X-ray revealed a mass in the right mediastinum. Ultrasound and CT-scan of the chest showed a multiloculated mass at the right posterior mediastinum. Fine needle aspiration biopsy of the mass confirmed a teratoma.
    Study site: Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia
    Matched MeSH terms: Teratoma/congenital*; Teratoma/pathology
  10. Liew WX, Lam HY, Narasimman S, Navarasi S, Mohd Hamzah K
    Med J Malaysia, 2016 02;71(1):32-4.
    PMID: 27130743
    Mediastinal teratoma is an infrequent germ cell tumour and comprises of 1 to 5% of all mediastinal tumours. We report a case of mediastinal mature teratoma in a 12 year old boy who presented to us with persistent non-productive cough, fever and dyspnoea for the past 7 months. Computed tomographic scan of thorax revealed a large anterior mediastinal mass measuring 11.2x9.9x14cm with calcification within. He subsequently underwent a median sternotomy with left subcostal extension (L-incision) and excision of tumour. Histopathology of the tumour revealed a mature cystic teratoma. We would like to report a case of successful surgical management of a large mediastinal mature teratoma in a child.
    Matched MeSH terms: Teratoma/surgery
  11. Jayaram G, Cheah PL, Yip CH
    Acta Cytol., 2000 May-Jun;44(3):375-9.
    PMID: 10833994
    BACKGROUND: Teratoma of the thyroid in adults is extremely rare, and most are malignant. Only nine cases have been adequately documented in the English-language literature, and there are no reports detailing the fine needle aspiration (FNA) cytologic characteristics.

    CASE: A 32-year-old female presented with a left-sided nodular thyroid mass with left cervical lymphadenopathy. FNA cytology of the thyroid and lymph nodes was done. The cytologic and immunocytochemical features were that of a small round cell tumor with neuroepithelial (NE) differentiation, metastasizing to the cervical nodes. Microscopic study of the thyroidectomy specimen showed a tumor showing an NE pattern with occasional islands of squamous and cuboidal epithelium, leading to a diagnosis of malignant teratoma.

    CONCLUSION: Knowledge of FNA cytologic features of rare but highly malignant lesions like thyroid teratomas allow early recognition so that suitable and possibly aggressive treatment protocols can be adopted in the hope of prolonging survival.
    Matched MeSH terms: Teratoma/pathology*
  12. Lal M
    Med J Malaya, 1971 Jun;25(4):307-10.
    PMID: 4261309
    Matched MeSH terms: Teratoma/diagnosis
  13. MARSDEN AT
    Med J Malaya, 1959 Dec;14:106-10.
    PMID: 14421490
    Matched MeSH terms: Teratoma*
  14. Thambi Dorai CR, Muthu Alhagi V, Chee Eng N, Ismail Z, Yakub A
    Pediatr Surg Int, 1998 Nov;14(1-2):84-5.
    PMID: 9880705
    A neonate with severe respiratory distress due to a benign mediastinal teratoma (MT) is reported. Despite early and easy surgical excision of the tumor, the child died due to poor cardiac function. Only ten cases of MT in neonates have been reported in the literature so far. While the tumor has been known to interfere with lung development in utero, postnatal myocardial dysfunction due to poor heart development has not been previously documented.
    Matched MeSH terms: Teratoma/complications; Teratoma/congenital*; Teratoma/epidemiology
  15. Siti Aishah MA, Tham KY, Samy M
    Family Physician, 1990;2:30-32.
    471 ovarian tumours were available for study from 1980 to 1987. Epidemiological breakdown by race, age and the histological type of the tumours was obtained. The diagnosis of the individual tumours was based on the World Health Organisation (WHO) histological classification of ovarian tumours. There were 324 (68.8%) benigh and 147 (31.2%) malignant tumours. 253 (53.7%) of the tumours were seen in the Malays. The third decade was the peak age for the benigh tumours, and for the malignant tumours, the fourth and fifth decades. 138 (42.6%) of the benign ovarian tumours were cystic teratomas and 45 (30.6%) of the malignant tumours were cystadenocarcinoma.
    Matched MeSH terms: Teratoma
  16. Quah BS, Menon BS
    Clin Genet, 1996 Oct;50(4):232-4.
    PMID: 9001806
    Down syndrome may be associated with many complications. Among the malignancies associated with Down syndrome, leukaemia is the most common. This is a case report of a patient with Down syndrome associated with both a retroperitoneal teratoma and a Morgagni hernia.
    Matched MeSH terms: Teratoma/complications*
  17. Ahluwalia HS, Sharma DC
    Med J Malaysia, 1973 Mar;27(3):223-4.
    PMID: 4268930
    Matched MeSH terms: Teratoma/pathology*
  18. Abdul Rashid S, Ab Hamid S, Mohamad Saini S, Muridan R
    Biomed Imaging Interv J, 2012 Apr;8(2):e11.
    PMID: 22970067 MyJurnal DOI: 10.2349/biij.8.2.e11
    Diagnosing acute appendicitis in children can be difficult due to atypical presenting symptoms. While there are reported cases of acute appendicitis or appendiceal masses causing unilateral hydronephrosis, bilateral hydronephrosis as a complication of appendiceal mass is very rare. We report a case of a child who presented with cardinal symptomatology associated with the urogenital tract. Ultrasound (US) investigation showed a pelvic mass causing bilateral hydronephrosis. An initial diagnosis of a pelvic teratoma was made based on the US and computed tomography (CT) scan findings. The final diagnosis of an appendiceal mass causing bilateral hydronephrosis was established intraoperatively.
    Matched MeSH terms: Teratoma
  19. Win TT, Razy N, Hamid S, Ubramanian AB, Ramalinggam G
    Turk Patoloji Derg, 2014;30(3):220-4.
    PMID: 24715558 DOI: 10.5146/tjpath.2013.01220
    Teratoma of the neck is a rare extra-gonadal teratoma. Although it can be seen in adult, most of the cases present in fetal life or early childhood. Grading and classification of teratoma is important for management and prognosis. Decision making between mature and immature teratoma is sometime challenging if it is not composed of extensive unusual neuroectodermal tissue component. We reported a rare case of huge congenital mature cystic teratoma composted of various neuroectodermal tissues in an 8-month-old boy; it was located at the lateral neck and mimicked congenital cystic hygroma. A literature review was done to grade and classify the tumour.
    Matched MeSH terms: Teratoma/congenital; Teratoma/diagnosis*
  20. Shahizon AM, Mohd Zaki F, Julian MR, Hanafiah M
    BMJ Case Rep, 2014;2014.
    PMID: 24493108 DOI: 10.1136/bcr-2013-200862
    Matched MeSH terms: Teratoma/complications; Teratoma/surgery*
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