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Strategi pembelajaran pelajar perubatan dan pergigian di institusi pengajian tinggi

Fadzilah Siraji, Yong Zulina Zubairi, Abdul Razak Saleh, Rohana Jani, Md. Yusoff Abu Bakar, Md. Radzi Johari

CREAM : Current Research in Malaysia (Penyelidikan Terkini di Malaysia), 2012;1(1):73-88.
MyJurnal

Learning Strategy and Study Inventory (LASSI) merupakan suatu instrumen laporan kendiri yang digunakan untuk menilai strategi pembelajaran berdasarkan model umum pembelajaran kognitif dan model strategik pembelajaran. untuk mendapatkan maklumat tentang strategi pembelajaran pelajar Perubatan dan Pergigian di Institusi Pengajian Tinggi Awam (IPTA) dan Swasta (IPTS). Instrumen yang telah dibangunkan oleh LASSI diadaptasi dan digunapakai. Tiga komponen utama yang diukur dalam LASSI iaitu KEMAHuAn, KEMAHIrAn dan PErATurAn KEnDIrI. Populasi kajian merangkumi pelajar lepasan STPM dan Matrikulasi dari IPTA dan IPTS yang mengikuti program Perubatan serta Pergigian atau program Perubatan sahaja. Secara keseluruhannya, persepsi pelajar menunjukkan keperihatinan pelajar untuk mempelajari maklumat baru, sikap dan minat terhadap bidang yang dipelajari dan disiplin diri amat rendah berbanding pelajar di negara maju. Perbandingan skor pelajar IPTA dan IPTS menunjukkan terdapat perbezaan bagi faktor Kebimbangan, Pemprosesan Maklumat dan Strategi Pengujianan. Perbandingan skor pelajar lepasan Matrikulasi dan STPM pula menunjukkan tiada perbezaan signifikan bagi hampir semua skor bagi faktor LASSI kecuali Mat Bantu Pembelajaran dan Pengujian Kendiri. Perbandingan skor pelajar Perubatan dan Pergigian pula menunjukkan strategi pembelajaran bagi kedua dua kumpulan pelajar yang mengikuti bidang kritikal tersebut adalah sama dengan tiada sebarang perbezaan yang signifikan dalam sebarang faktor LASSI. Dapatan kajian juga menunjukkan bahawa keseluruhan pelajar yang mengikuti program kritikal mempunyai strategi pembelajaran yang kurang baik. Sehubungan itu pihak pengurusan perlu mengambil inisiatif untuk membantu pelajar dalam memperkemaskan strategi pembelajaran mereka. Strategi pembelajaran yang kurang efektif akan mengundang kesan sampingan yang tidak sihat seperti kemurungan atau stress di kalangan pelajar.

Matched MeSH terms: Intestinal Atresia
Transformasi gen metalotionin (eiMT1) daripada eleusine indica ke dalam pokok tembakau, nicotiana tabacum berperantaraan agrobacterium tumefaciens

Nik Marzuki Sidik, Roslina Mat Yazid, Che Radziah Che Mohd. Zain, Ismanizan Ismail

Sains Malaysiana, 2010;39.

Metalotionin (MT ) merupakan protein pengikat logam berberat molekul rendah dan kaya dengan sistein yang hadir dalam pelbagai jenis organisma termasuklah bakteria, kulat, tumbuhan dan haiwan. MT tumbuhan dipercayai mengambil bahagian dalam metabolisme dan penyahtoksikan logam dengan cara pengkelatan ion-ion logam berat. Fungsinya yang unik ini telah mendorong minat untuk memencilkan gen MT daripada rumput sambau, Eleusine indica. DNA pelengkap (cDNA) eiMT 1 telah diklonkan ke dalam vektor binari pBI121 untuk ditransformasikan ke dalam pokok tembakau melalui perantaraan Agrobacterium tumefaciens. Penyaringan pokok tembakau transgenik dengan PCR dilakukan menggunakan 3 pasang pencetus yang direka khas iaitu pasangan CMT F dan CMT R, 35SF dan PMT R, dan pasangan pencetus khusus-gen MT FS2 dan MT RS2. Ketiga-tiga pasangan pencetus ini berjaya menghasilkan saiz serpihan DNA jangkaan iaitu masing-masing 270 pb, 1.1 kb dan 170 pb. Penjujukan terhadap serpihan bersaiz 170 pb dan analisis jujukan menunjukkan persamaan 100 % dengan eiMT 1. Kajian pengekspresan gen melalui pendekatan transkripsi berbalik-PCR membuktikan bahawa transgen eiMT 1 telah berjaya diekspreskan dalam 11 daripada 19 pokok transgenik yang dikaji.

Matched MeSH terms: Intestinal Atresia
Fulltext Meconium peritonitis: prenatal diagnosis and postnatal management--a case report

Ramesh JC, Chow TWP, Yik YI, Ramanujam TM

Med J Malaysia, 1999 Dec;54(4):528-30.
PMID: 11072477

The management of a case of antenatally diagnosed meconium peritonitis (MP) due to intrauterine intestinal perforation secondary to bowel atresia is reported. The literature is reviewed with reference to the significance and outcome of antenatally diagnosed MP.

Matched MeSH terms: Intestinal Atresia/complications; Intestinal Atresia/embryology
Congenital atresia and stenosis of the duodenum--a case report

Lal M, Said MY

Med J Malaysia, 1974 Jun;28(4):283-6.
PMID: 4278623
Matched MeSH terms: Intestinal Atresia/complications*; Intestinal Atresia/surgery
A rare case of intrauterine intussusception causing ileal atresia

Carine Sun CY, Ashok K, Mughni B

Med J Malaysia, 2020 05;75(3):304-306.
PMID: 32467551

Intrauterine intussusception is a rare but evident cause of intestinal atresia and is usually detected intraoperatively. We report on a term neonate who presented to the Department of Paediatric Surgery, Sabah Women and Children's Hospital, Malaysia with delayed passage of meconium and intestinal obstruction, wherein the lower contrast showed a claw sign. This was a good clue that this neonate had intrauterine intussusception and this suspicion was confirmed upon laparotomy. We found an ileo-ileal intussusception causing ileal atresia, requiring resection and primary anastomosis.

Matched MeSH terms: Intestinal Atresia/etiology; Intestinal Atresia/surgery*
Fulltext Prenatal diagnosis of intestinal obstruction due to ileal atresia

Raman S, Chan LL, Chang KW, Rachagan SP

Med J Malaysia, 1992 Sep;47(3):228-30.
PMID: 1491650

A case of intestinal obstruction due to ileal atresia where the diagnosis was made prenatally by ultrasound is presented. Close monitoring of the fetus was done ultrasonographically to look for any evidence of meconium peritonitis. The baby was delivered preterm but weighed 3.3 kg. Laparotomy and enterostomy was done and the baby is currently well.

Matched MeSH terms: Intestinal Atresia/ultrasonography*
Compound heterozygous mutations in TTC7A cause familial multiple intestinal atresias and severe combined immunodeficiency

Yang W, Lee PP, Thong MK, Ramanujam TM, Shanmugam A, Koh MT, et al.

Clin Genet, 2015 Dec;88(6):542-9.
PMID: 25534311 DOI: 10.1111/cge.12553

Familial multiple intestinal atresias is an autosomal recessive disease with or without combined immunodeficiency. In the last year, several reports have described mutations in the gene TTC7A as causal to the disease in different populations. However, exact correlation between different genotypes and various phenotypes are not clear. In this study, we report identification of novel compound heterozygous mutations in TTC7A gene in a Malay girl with familial multiple intestinal atresias and severe combined immunodeficiency (MIA-SCID) by whole exome sequencing. We found two mutations in TTC7A: one that destroyed a putative splicing acceptor at the junction of intron 17/exon 18 and one that introduced a stop codon that would truncate the last two amino acids of the encoded protein. Reviewing the recent reports on TTC7A mutations reveals correlation between the position and nature of the mutations with patient survival and clinical manifestations. Examination of public databases also suggests carrier status for healthy individuals, making a case for population screening on this gene, especially in populations with suspected frequent founder mutations.

Matched MeSH terms: Intestinal Atresia
Fulltext Isolated Ascites in a Monochorionic Twin after Fetoscopic Laser Ablation Is Not Necessarily Secondary to Recurrence or Anaemia: Bowel Complications in Twin-to-Twin Transfusion Syndrome after Fetoscopic Laser Ablation

Tan LN, Cheung KW, Philip I, Ong S, Kilby MD

Fetal Diagn Ther, 2019;45(5):285-294.
PMID: 30554214 DOI: 10.1159/000494616

BACKGROUND/PURPOSE: We report a case study of jejunal atresia and the results of a systematic literature review of all reported cases of bowel complications occurring after fetoscopic laser ablation (FLA) for the treatment of twin-to-twin transfusion syndrome (TTTS).
METHODS: A systematic literature review was performed of bowel complications after FLA for TTTS according to PRISMA guidelines.
RESULTS: There are 11 published cases of small bowel atresia, 5 cases of necrotising enterocolitis (NEC), and 2 cases with foetal bowel perforations. Recipient twins were more likely to be affected by small bowel atresia (7 recipient and 4 donor cases) and NEC (3 recipient and 2 donor twins). Prenatal ultrasonographic abnormalities were demonstrated in 7 out of 9 cases with bowel atresia and in both cases of bowel perforation. The overall survival rate for neonates with bowel complications after FLA is 72%, but is much lower for co-twins at 22%. The survival rates for jejunoileal atresia and NEC are 91 and 40%, respectively.
CONCLUSIONS: It is uncertain as to whether these bowel anomalies are due to bowel ischaemia associated with TTTS, the treatment with FLA, or a combination of both. Cases with prenatal abdominal ultrasonographic abnormalities after FLA should have close prenatal and postnatal assessment to detect bowel complications.

Matched MeSH terms: Intestinal Atresia/surgery