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  1. Fulltext Case report--a neonate with nonimmune hydrops fetalis
    Ram SP, Ariffin WA, Kassim Z
    Singapore Med J, 1993 Oct;34(5):459-61.
    PMID: 8153701
    A post-dated intra-uterine growth retarded male Malay baby was born to a 30-year-old mother gravida II by Caesarean section. Her previous pregnancy ended in still-birth. The baby was severely asphyxiated at birth. He was intubated and immediately admitted to the neonatal intensive care unit. He had anasarca, anaemia, purpura and firm, massive hepatosplenomegaly. X-rays revealed ascites and bilateral metaphysiitis of the long bones. The haemoglobin level was 5.0 gm/dl and PCV 18.3%. Coombs' test was negative. Prothrombin time (PT) and partial thromboplastin time (PTT) were prolonged. The baby and mother were positive for Venereal Disease Research Laboratory (VDRL) and the treponema pallidum haemagglutination assay (TPHA) tests. The baby was actively resuscitated but expired at three and a half hours of life due to overwhelming sepsis associated with severe anaemia and disseminated intravascular coagulation.
    Matched MeSH terms: Fetal Growth Retardation/etiology
  2. Factors associated with the incidence of low birth weight in Pontianak City, Indonesia
    Hastuti L, Litasari A, Kardiatun K, Mardiyani R, Rahmawati A, Jais S
    Med J Malaysia, 2024 Nov;79(6):757-763.
    PMID: 39614795
    INTRODUCTION: The weight of an infant at the time of birth is an indicator of its health. Infants with low birth weight (LBW) are at a higher risk of neonatal mortality and morbidity as well as stunted growth. Low birth weight (LBW) remains a public health concern in developing countries, such as Indonesia. In fact, the neonatal mortalities and morbidities that occur as a consequence of LBW can be prevented by addressing the relevant risk factors. It is believed that by identifying these risk factors, prevention and management efforts can be efficiently and effectively implemented to reduce incidences of LBW (LBWIs). As such, the present study determined the factors affecting LBWIs in a rural setting in Pontianak City, Indonesia.

    MATERIALS AND METHODS: This is a retrospective unmatched case-control study. The required data was obtained from the medical records maintained by the University Tanjungpura Hospital, Pontianak City, Indonesia. Simple random sampling was used to select and equally divide the 60 chosen respondents into LBW case and normal birth weight control groups.

    RESULTS: Mothers with low educational levels had a 1.5 times greater chance of giving birth to LBW babies. The results of the multivariate analysis also revealed a correlation between gestational age (GA), incidence of premature rupture of membranes (PROM), and intrauterine growth restriction (IUGR) and that their combined effects that contributed to 56% of LBWIs.

    CONCLUSION: Low maternal education level, low gestational age, IUGR, and premature rupture of membranes contribute to LBW babies. This study recommends that it is necessary to educate women of childbearing age about routine antenatal care checks to identify risk factors that can lead to LBW.

    Matched MeSH terms: Fetal Growth Retardation/etiology
  3. Fulltext Maternal melanoma with placental metastasis
    Shuhaila A, Rohaizak M, Phang KS, Mahdy ZA
    Singapore Med J, 2008 Mar;49(3):e71-2.
    PMID: 18362990
    A 40-year-old woman, a grand multipara with uncertain gestation, presented with severe, prolonged diarrhoea. She was previously diagnosed to have melanoma. Examination revealed gross ascites with hepatosplenomegaly and uterus corresponding to 29 weeks gestation. An emergency caesarean section confirmed widespread metastases to the ovaries, mesentery and placenta. A viable male foetus was delivered with features of intrauterine growth restriction. The baby survived, but the mother died a week later. This case highlights the importance of thoroughly assessing placentas and babies of patients with melanoma for metastases.
    Matched MeSH terms: Fetal Growth Retardation/etiology
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