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  1. Irfan M, Shahid H, Yusri MM, Venkatesh RN
    Med J Malaysia, 2011 Jun;66(2):150-1.
    PMID: 22106700 MyJurnal
    Schwannoma in the head and neck region is very rare. The tumour occurring in the intraparotid facial nerve is even rarer. A patient presenting with a parotid swelling with facial nerve paralysis is not pathognomonic of a facial nerve schwannoma. However it may occur because enlargement of the parotid, by any kind of tumour especially a malignant one can cause facial nerve paralysis. We report a case of an intraparotid facial nerve schwannoma, in a patient who presented with parotid enlargement and facial nerve paralysis.
    Matched MeSH terms: Cranial Nerve Neoplasms/diagnosis*; Cranial Nerve Neoplasms/surgery
  2. Zulkiflee AB, Prepageran N, Rahmat O, Jayalaskhmi P, Sharizal T
    Ear Nose Throat J, 2012 Nov;91(11):E26-9.
    PMID: 23288802
    We report a case of primary extracranial meningioma arising from the hypoglossal nerve in a 54-year-old man who presented with a 9-month history of hoarseness and progressive dysphagia. He had also noticed that his tongue was deviated to the left and, as a result, he was having difficulty pronouncing words. Examination revealed fasciculation and muscle wasting on the left side of the tongue. Other cranial nerve functions were normal. Contrast-enhanced computed tomography detected a heterogeneous mass that had arisen above the bifurcation of the left common carotid artery and had extended to near the skull base. Transcervical excision of the tumor was performed, and histopathology identified it as a meningioma of the hypoglossal nerve. The patient recovered uneventfully, and he was without recurrence at more than 2 years of follow-up. A primary extracranial meningioma is extremely rare, and its presentation may be subtle. A thorough investigation is necessary to avoid fatal compressive symptoms.
    Matched MeSH terms: Cranial Nerve Neoplasms/diagnosis*; Cranial Nerve Neoplasms/surgery
  3. Prasad U, Doraisamy S
    Eur J Surg Oncol, 1991 Oct;17(5):536-40.
    PMID: 1936303
    Five rare cases of nasopharyngeal carcinoma with optic nerve involvement are reported. Computerised Tomographic Scan (CT Scan) studies were performed in four of them. Evidence of intracranial spread of the tumour, from the roof of the fossa of Rosenmuller to the apex of the orbit through the cavernous sinus, was noted in three patients. In one of them there was extracranial extension of the tumour, to the orbit through the posterior ethmoid.
    Matched MeSH terms: Cranial Nerve Neoplasms/pathology*; Cranial Nerve Neoplasms/radiography
  4. Abdullah A, Mahmud MR, Sabir HA, Saim L
    Med J Malaysia, 2003 Aug;58(3):450-3.
    PMID: 14750390
    Facial nerve schwannomas are rare benign tumors. The tumor can arise anywhere along the course of the facial nerve. The most common presentation for this tumor is a slowly progressive facial nerve paralysis. Sensorineural hearing loss (SNHL) and tinnitus are later symptoms. The symptoms and signs depend on the site of tumor along the nerve. We report three cases of facial nerve schwannomas with different clinical presentations. Appropriate management of a facial nerve schwannoma should be based on the site and extent of the tumor and status of the nerve function.
    Matched MeSH terms: Cranial Nerve Neoplasms/complications; Cranial Nerve Neoplasms/diagnosis*
  5. Ng JJ, Ong HY, Nasseri Z, Azmi MI, Abdullah A
    Cureus, 2021 Jan 08;13(1):e12584.
    PMID: 33457146 DOI: 10.7759/cureus.12584
    Facial nerve tumors constitute about 5% of all facial nerve paralysis. As it is relatively uncommon, it could be misdiagnosed. We encountered an 18-year-old girl who had right facial weakness since the age of four, referred to otorhinolaryngology clinic for further evaluation only when her hearing deteriorated and the facial weakness worsened. Further investigation revealed facial nerve schwannoma. Facial nerve paralysis in the pediatric age group is uncommon and should be examined in detail to rule out other possible etiologies besides Bell's palsy.
    Matched MeSH terms: Cranial Nerve Neoplasms
  6. Tevaraj JM, Li Min ET, Mohd Noor RA, Yaakub A, Wan Hitam WH
    Case Rep Ophthalmol Med, 2016;2016:1701509.
    PMID: 27738538
    Neurofibromatosis type 2 usually presents with bilateral acoustic schwannomas. We highlight the rare presentation of neurofibromatosis initially involving third nerve. A 23-year-old Malay female presented with left eye drooping of the upper lid and limitation of upward movement for 8 years. It was associated with right-sided body weakness, change in voice, and hearing disturbance in the right ear for the past 2 years. On examination, there was mild ptosis and limitation of movement superiorly in the left eye. Both eyes had posterior subcapsular cataract. Fundoscopy showed generalised optic disc swelling in both eyes. She also had palsy of the right vocal cord, as well as the third and eighth nerve. There was wasting of the distal muscles of her right hand, with right-sided decreased muscle power. Pedunculated cutaneous lesions were noted over her body and scalp. MRI revealed bilateral acoustic and trigeminal schwannomas with multiple extra-axial lesions and intradural extramedullary nodules. Patient was diagnosed with neurofibromatosis type 2 and planned for craniotomy and tumour debulking, but she declined treatment. Neurofibromatosis type 2 may uncommonly present with isolated ophthalmoplegia, so a thorough physical examination and a high index of suspicion are required to avoid missing this condition.
    Matched MeSH terms: Cranial Nerve Neoplasms
  7. Mat Baki M, Clarke P, Birchall MA
    J Laryngol Otol, 2018 Sep;132(9):846-851.
    PMID: 30180919 DOI: 10.1017/S0022215118000476
    OBJECTIVE: This prospective case series aimed to present the outcomes of immediate selective laryngeal reinnervation.

    METHODS: Two middle-aged women with vagal paraganglioma undergoing an excision operation underwent immediate selective laryngeal reinnervation using the phrenic nerve and ansa cervicalis as the donor nerve. Multidimensional outcome measures were employed pre-operatively, and at 1, 6 and 12 months post-operatively.

    RESULTS: The voice handicap index-10 score improved from 23 (patient 1) and 18 (patient 2) at 1 month post-operation, to 5 (patient 1) and 1 (patient 2) at 12 months. The Eating Assessment Tool 10 score improved from 20 (patient 1) and 24 (patient 2) at 1 month post-operation, to 3 (patient 1) and 1 (patient 2) at 12 months. There was slight vocal fold abduction observed in patient one and no obvious abduction in patient two.

    CONCLUSION: Selective reinnervation is safe to perform following vagal paraganglioma excision conducted on the same side. Voice and swallowing improvements were demonstrated, but no significant vocal fold abduction was achieved.

    Matched MeSH terms: Cranial Nerve Neoplasms/surgery*
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