MyMedR

Fulltext Bilateral cavernous sinus and left dural sigmoid sinus thrombosis associated with extreme exertion: a case report

Wern-Yih C, Jan-Bond C, Sudha M, Norlelawati A, Shatriah I

Arq Bras Oftalmol, 2021 1 21;84(1):83-86.

PMID: 33470347 DOI: 10.5935/0004-2749.20210013

Septic cavernous sinus thrombosis is a rare but often debilitating and potentially fatal disease. We describe a case of bilateral orbital cellulitis with rapidly progressing cavernous sinus thrombosis and left sigmoidal sinus thrombosis in an immunocompetent 20-year-old military man who had undergone intensive physical training. The patient presented with rapid painful swollen left eye for 2 days. The examination results were gross proptosis with total ophthalmoplegia. He was treated with intravenous antibiotics and corticosteroid. At 1 week, visual acuity improved to 20/20 OU, with a normal intraocular pressure. There was a significant improvement in proptosis. The ocular motility of the right eye was fully restored, with slight residual ophthalmoplegia in the left eye. There was no residual illness or recurrence of illness at 3 months' follow-up.

Matched MeSH terms: Orbital Cellulitis*

Bullous cellulitis as an extraordinary manifestation of a Vibrio cholerae O1 Ogawa infection

Ummu SF, Ding CH, Wahab AA, Tzar MN

Trop Biomed, 2023 Jun 01;40(2):170-173.

PMID: 37650403 DOI: 10.47665/tb.40.2.007

Vibrio cholerae is a gram-negative bacterium synonymous with its namesake disease, cholera. Thus, gastrointestinal symptoms are the norm and V. cholerae is very rarely associated with skin and soft tissue infections. We describe a case of a 63-year-old Chinese woman with multiple medical comorbidities on corticosteroid therapy who developed fever and a painful swelling on her left leg after being pricked by a branch while gardening. There was no abdominal pain, vomiting or diarrhea. A diagnosis of bullous cellulitis was made clinically, and blood was sent for bacteriological culture. A beta-hemolytic commashaped gram-negative bacillus was isolated from the blood. It was also oxidase-positive and produced an acid/alkaline (A/K) reaction on triple sugar iron agar. It was identified biochemically as Vibrio cholerae. After additional testing, it was found to be of the O1 serogroup and Ogawa serotype. The infection resolved following a 10-day course of high-dose co-trimoxazole therapy.

Matched MeSH terms: Cellulitis/diagnosis; Cellulitis/drug therapy

Bilateral orbital cellulitis due to Neisseria gonorrhoeae and Staphylococcus aureus: a previously unreported case

Raja NS, Singh NN

J Med Microbiol, 2005 Jun;54(Pt 6):609-611.

PMID: 15888472 DOI: 10.1099/jmm.0.46031-0

Cellulitis of the orbit is a common cause of proptosis in children, and also frequently arises in the elderly and the immunocompromised. The condition is characterized by infection and swelling of the soft tissues lining the eye socket, pushing the eye ball outwards and causing severe pain, redness, discharge of pus and some degree of blurred vision. There is a small risk of infection spreading to the meninges of the brain and causing meningitis. This paper reports the case of an adult in whom polymicrobial bilateral orbital cellulitis had developed due to Staphylococcus aureus and Neisseria gonorrhoeae infection. N. gonorrhoeae infections are acquired by sexual contact. Although the infection may disseminate to a variety of tissues, it usually affects the mucous membranes of the urethra in males and the endocervix and urethra in females. To the authors' knowledge this is the first report of polymicrobial bilateral orbital cellulitis due to S. aureus and N. gonorrhoeae in medical literature.

Matched MeSH terms: Cellulitis/complications; Cellulitis/diagnosis; Cellulitis/microbiology*

Cellulitis in human brucellosis: An atypical presentation

Subramaniam K, Ali SU

Malays J Pathol, 2019 Dec;41(3):359-364.

PMID: 31901923

INTRODUCTION: Brucellosis is a zoonotic disease with variable clinical manifestations and atypical presentation in humans. Human brucellosis cases are not seen often in Malaysia.

CASE REPORT: This is a case report of 19 years old gentleman who presented with fever, lower limb redness, pain and swelling. He was initially treated as cellulitis. However, based on the recovery of Brucella melitensis from his blood culture, he was later diagnosed to have brucellosis. He had a history of consumption of fresh goat's milk and uncooked meat which could have been the possible modes of transmission. Brucella serology IgM and IgG were both positive, and anti-Brucella immunocapture agglutination test (BrucellaCapt) was also positive with a titer of 1:2560. He was treated with six weeks of oral doxycycline 100 mg twice daily and oral rifampin 450 mg twice daily.

DISCUSSION: This is a case of human brucellosis with atypical cutaneous involvement.

Matched MeSH terms: Cellulitis/diagnosis; Cellulitis/microbiology*; Cellulitis/pathology*

Fulltext A fatal case of Vibrio vulnificus cellulitis with septicaemia

Zetti ZR, Norazlah B, Raha AR

Med J Malaysia, 2009 Sep;64(3):246-7.

PMID: 20527281 MyJurnal

Vibrio vulnificus is a gram-negative marine bacterium that may cause local wound infection, distinctive soft tissue infection, gastroenteritis and septicaemia with a high mortality rate. A healthy man presented with severe abdominal pain, diarrhoea and fever followed by development of multiple blisters, cellulitis and necrotizing fasciitis of the lower limbs, who progressed rapidly to fulminant sepsis caused by this organism. Vibrio vulnificus septicaemia should be suspected in the presence of sepsis and progressive soft-tissue infection with recent history of raw seafood consumption.

Matched MeSH terms: Cellulitis/microbiology*

Fulltext Pseudomonas aeruginosa bacteremia secondary to acute right leg cellulitis: case of community-acquired infection

Wahab AA, Rahman MM

EXCLI J, 2013;12:997-1000.

PMID: 27034639

Pseudomonas aeruginosa is a gram-negative bacillus that causes wide spectrum clinical infections. However, it is most frequently associated with hospital-acquired infection. In this case a 58-year-old male with underlying hypertension and dyslipidaemia was admitted for acute right leg cellulitis. Pseudomonas aeruginosa was identified from the case, though it was not a usual suspected organism. It might be due to community-acquired infection.

Matched MeSH terms: Cellulitis*

Fulltext Cutaneous tuberculosis mimicking cellulitis in an immunosuppressed patient

Chin PW, Koh CK, Wong KT

Singapore Med J, 1999 Jan;40(1):44-5.

PMID: 10361486

A 28-year-old lady suffering from systemic lupus erythomatosus (SLE) with diffuse proliferative glomerulonephritis (DPGN) and who was on oral cyclophosphamide and prednisolone presented with left lower limb 'cellulitis'. The 'cellulitis' of the left lower limb failed to respond to usual antibiotics which prompted evaluation of the clinical diagnosis. The diagnosis is made based on the presence of granulomas, multinucleated giant cells and acid fast bacilli on the skin biopsy.

Matched MeSH terms: Cellulitis/diagnosis*

Clinical characteristics of patients with lower limb cellulitis and antibiotic usage in Hospital Kuala Lumpur: a 7-year retrospective study

Ch'ng CC, Johar A

Int J Dermatol, 2016 Jan;55(1):30-5.

PMID: 26275796 DOI: 10.1111/ijd.12850

Cellulitis commonly involved lower limbs. This study was carried out to determine the demography, clinical characteristics, risk factors, microbiological aspects, and antibiotics usage in this group of patients in Hospital Kuala Lumpur.

Matched MeSH terms: Cellulitis

Fulltext Hidden germ of the immunocompromised: a case of fungal orbital cellulitis

Er, L.Z., Johar, M.J.

Medicine & Health, 2019;14(2):266-270.

MyJurnal

Orbital cellulitis is an infection of the orbital soft tissue that could possibly lead to serious complications if treatment is delayed. It is important to differentiate this condition from a less life-threatening condition like preseptal cellulitis as orbital cellulitis would require a more aggressive treatment than the former condition. The present case discusses about a patient who was diagnosed with orbital cellulitis and developed complications from the disease. The delayed administration of the appropriate antibiotic subsequently led to the patient’s death. The delay was because of the reason that the patient belonged to the immunocompromised group who harbour different causative organism than the normal population.

Matched MeSH terms: Orbital Cellulitis

Cellulitis due to Shewanella algae: Crucial diagnostic clues from basic microbiological tests

Ding CH, Wahab AA, Muttaqillah NAS, Kamarudin N, Saarah WR

Trop Biomed, 2019 Dec 01;36(4):883-887.

PMID: 33597461

Shewanella spp. are infrequently implicated in human infections but they are emerging pathogens with particular significance in regions with warm climates, such as Southeast Asia. This is a case of a middle-aged diabetic and hypertensive man who presented with worsening congestive heart failure symptoms associated with fever and a painful right leg. His right leg had numerous scabs and was tender, warm and erythematous. He was provisionally diagnosed with decompensated heart failure precipitated by cellulitis and uncontrolled hypertension. His blood grew non-fermentative, oxidase-positive and motile gram-negative bacilli which produced hydrogen sulfide on triple sugar iron agar. When cultured on blood agar, mucoid and weakly β-haemolytic colonies were observed after 48 hours. API 20 NE named the isolate as Shewanella putrefaciens but 16S rRNA sequence analysis identified the organism as Shewanella algae. The patient was treated with a 10-day course of ceftazidime, which resulted in the resolution of the cellulitis.

Matched MeSH terms: Cellulitis/diagnosis; Cellulitis/microbiology*

Subcutaneous gas in diabetes mellitus due to Aerobacter aerogenes infection

Da Costa JL

Med J Malaya, 1969 Mar;23(3):199-202.

PMID: 4240074

Matched MeSH terms: Cellulitis/diagnosis; Cellulitis/etiology*

Cellulitis: An unusual manifestation of Neisseria meningitidis infection

Muhd Yusoff NH, Zainol Rashid Z, Sulong A, Shafiee MN, Ismail Z

Malays J Pathol, 2019 Dec;41(3):351-354.

PMID: 31901921

INTRODUCTION: Neisseria meningitidis infections often cause severe meningitis as well as bacteraemia. However, cellulitis in meningococcal diseases have rarely been described. Here, we report a case of right lower limb cellulitis caused by N. meningitidis.

CASE REPORT: A 69-year-old woman presented with fever and lower limb swelling. She had diabetes mellitus, hypertension, dyslipidaemia and a history of surgical resection of vulvar carcinoma. N. meningitidis was isolated from her blood culture.

DISCUSSION: This report provides additional evidence in support of N. meningitidis as a cause of cellulitis.

Matched MeSH terms: Cellulitis/diagnosis; Cellulitis/pathology*

Chaetomium globosum Cutaneous Fungal Infection Confirmed by Molecular Identification: A Case Report from Malaysia

Mohd Tap R, Sabaratnam P, Ahmad NA, Abd Razak MF, Hashim R, Ahmad N

Mycopathologia, 2015 Aug;180(1-2):137-41.

PMID: 25894509 DOI: 10.1007/s11046-015-9890-5

An 11-year-old girl presented with multiple blisters on her the right foot complicated with cellulitis. The conventional and molecular identification were performed on the culture. The internal transcribed spacer (ITS) region in rRNA gene of the isolate was amplified by PCR. The sequence of the amplified ITS region matched 99 % with that of Chaetomium globosum in the GenBank. This is the first report describing C. globosum causing cutaneous infection in Malaysia.

Matched MeSH terms: Cellulitis/diagnosis*; Cellulitis/etiology; Cellulitis/microbiology; Cellulitis/pathology*

Fulltext Clinical characteristics and outcomes of paediatric orbital cellulitis in Hospital Universiti Sains Malaysia: a five-year review

Mohd-Ilham I, Muhd-Syafi AB, Khairy-Shamel ST, Shatriah I

Singapore Med J, 2020 Jun;61(6):312-319.

PMID: 31598730 DOI: 10.11622/smedj.2019121

INTRODUCTION: Limited data is available on paediatric orbital cellulitis in Asia. We aimed to describe demographic data, clinical presentation, predisposing factors, identified microorganisms, choice of antibiotics and management in children with orbital cellulitis treated in a tertiary care centre in Malaysia.

METHODS: A retrospective review was performed on children with orbital cellulitis aged below 18 years who were admitted to Hospital Universiti Sains Malaysia, Kelantan, Malaysia, between January 2013 and December 2017.

RESULTS: A total of 14 paediatric patients fulfilling the diagnostic criteria for orbital cellulitis were included. Their mean age was 6.5 ± 1.2 years. Boys were more likely to have orbital cellulitis than girls (71.4% vs. 28.6%). Involvement of both eyes was observed in 14.3% of the patients. Sinusitis (28.6%) and upper respiratory tract infection (21.4%) were the most common predisposing causes. Staphylococcus aureus (28.6%) was the leading pathogen. Longer duration of hospitalisation was observed in those infected with methicillin-resistant Staphylococcus aureus and Burkholderia pseudomallei. 10 (71.4%) patients were treated with a combination of two or three antibiotics. In this series, 42.9% had surgical interventions.

CONCLUSION: Young boys were found to be more commonly affected by orbital cellulitis than young girls. Staphylococcus aureus was the most common isolated microorganism. Methicillin-resistant Staphylococcus aureus and Burkholderia pseudomallei caused severe infection. Sinusitis and upper respiratory tract infection were the most common predisposing factors. A majority of the children improved with medical treatment alone. Our findings are in slight disagreement with other published reports on paediatric orbital cellulitis, especially from the Asian region.

Matched MeSH terms: Orbital Cellulitis/microbiology*; Orbital Cellulitis/epidemiology*

Fulltext Cellulitis from terrestrial leech bite in a 2-month-old baby

Fahisham Taib, Suhailah Badruddin, Mohd Anas Che Nik, Ariffin Nasir, Ramiza Ramza Ramli

Malaysian Journal of Paediatrics and Child Health, 2018;24(2):1-3.

MyJurnal

Cellulitis in human following leech bite is rae, many of the case reports were associated with the use of medical leech. We report the first documented case of cellulitis following the bite of land leech (Haemodipsa species), known locally as 'pacat', in a 2 month-old-baby. The baby developed fever but subsided following an antibiotic cover. The baby had uneventful stay in the hospital and the cellulitis was successfully treated following a week cource of Cloxacillin.

Matched MeSH terms: Cellulitis

Fulltext Acute lymphangitis in a preschool child: a case report

Loh, Huai Seng

International e-Journal of Science, Medicine & Education, 2012;6(2):46-48.

MyJurnal

A 3-year old preschool boy presented with a pruritic red streak at the dorsum of his right foot traveling
upward from the affected site which was red and swollen. Insect sting was the more likely trigger which had caused the cellulitis and subsequently the acute lymphangitis.

Matched MeSH terms: Cellulitis

Fulltext Peritonsillar swelling is not always quinsy

Mohamad I, Yaroko A

Malays Fam Physician, 2013;8(2):53-5.

PMID: 25606284 MyJurnal

Quinsy is a common encounter in family physician practice. It is defined as a collection of purulent material in the peritonsillar space, giving appearance of unilateral palatal bulge. Presenting symptoms include trismus, muffled voice, odynophagia, and ipsilateral otalgia. When the diagnostic needle aspiration reveals no pus, the diagnosis is changed into peritonsillar cellulitis or also known as perintonsillitis. Peritonsillitis is sufficiently treated with antibiotics unlike a quinsy which warrants surgical incision and drainage.

Matched MeSH terms: Cellulitis

Fulltext Concurrent Mastoid Cellulitis and Langerhans Cells Histiocytosis:  A Challenging Diagnosis

Ong HY, Goh LC, Santhi K, Sha'ariyah MM

Oman Med J, 2018 Mar;33(2):167-170.

PMID: 29657688 DOI: 10.5001/omj.2018.31

Langerhans cell histiocytosis (LCH) is a rare proliferative disorder, which commonly arises in the bone and may involve other systems. To date, the diagnosis of temporal bone LCH remains a challenge as it may masquerade as a common ear infection. We report a case of a child who presented to us with persistent bilateral ear discharge for four months and was not responding to treatment. Her condition subsequently worsened, with clinical features and radiological findings suggestive of mastoid cellulitis. Nevertheless, further histopathology study revealed LCH.

Matched MeSH terms: Cellulitis

Fulltext Recurrent orbital cellulitis secondary to the ‘forgotten’ scleral buckle: a case report

Hor, S.M., Noor Aniah, A., Mushawiahti, M., Mushawiahti, M., Bastion, M.L.C.

Journal of Surgical Academia, 2017;7(2):49-52.

MyJurnal

Scleral buckle placement is a well-established technique for the treatment of primary rhegmatogenous retinal
detachment. Complications associated with scleral buckle are uncommon and its presentations can be vary. We
report a case of recurrent orbital cellulitis with anterior segment ischemia following a forgotten episode of previous
scleral buckling surgery, presenting with blurring of vision, redness and swelling of the lids. The presence of scleral
buckle was detected by detailed examination and confirmed by orbital imaging. Orbital infection and rubeosis iridis
were successfully treated with scleral buckle removal, intravenous antibiotics and intracameral ranibizumab.
However, the retinal detachment recurred and the visual acuity deteriorated to light perception. There was no further
intervention as the family declined in view of her old age. In cases of recurrent orbital infection, detailed clinical
examination is important to look for evidence of ocular prostheses as a source of infection. Orbital imaging is an
adjunct for making the diagnosis especially in cases where history is unreliable. Anterior segment ischemia due to
scleral buckle responds well to buckle removal with ranibizumab injection.

Matched MeSH terms: Orbital Cellulitis

Fulltext Canaliculitis in supernumerary puncta and canaliculi

Yong KC, Kah TA, Annuar FH

Clin Pract, 2011 Jul 01;1(3):e59.

PMID: 24765320 DOI: 10.4081/cp.2011.e59

We report the first case of supernumerary puncta and canaliculi presented with canaliculitis. A-59 year-old gentleman presented with painful swelling of the left lower lid for a week, which was associated with epiphora. The swelling was confined to the nasal aspect of the left lower lid (0.5×0.5 mm) with inflamed overlying skin. Two puncta (0.5 mm apart) were noted. The outer punctum at the normal anatomical position was a cul-de-sac while the inner punctum it the caruncle was patent. We described the embryology leading to supernumerary puncta and canaliculi to explain the paradoxical patency of the abnormally located punctum as well as the pathomechanism leading to canaliculitis. The patient was treated with oral cloxacillin 500 mg, 6 hourly for 5 days; the cellulitis subsided after three days.

Matched MeSH terms: Cellulitis

Displaying publications 1 - 20 of 41 in total