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Fulltext Accelerated Thermal Cycling Test of Microencapsulated Paraffin Wax/Polyaniline Made by Simple Preparation Method for Solar Thermal Energy Storage

Silakhori M, Naghavi MS, Metselaar HSC, Mahlia TMI, Fauzi H, Mehrali M

Materials (Basel), 2013 Apr 29;6(5):1608-1620.
PMID: 28809232 DOI: 10.3390/ma6051608

Microencapsulated paraffin wax/polyaniline was prepared using a simple in situ polymerization technique, and its performance characteristics were investigated. Weight losses of samples were determined by Thermal Gravimetry Analysis (TGA). The microencapsulated samples with 23% and 49% paraffin showed less decomposition after 330 °C than with higher percentage of paraffin. These samples were then subjected to a thermal cycling test. Thermal properties of microencapsulated paraffin wax were evaluated by Differential Scanning Calorimeter (DSC). Structure stability and compatibility of core and coating materials were also tested by Fourier transform infrared spectrophotometer (FTIR), and the surface morphology of the samples are shown by Field Emission Scanning Electron Microscopy (FESEM). It has been found that the microencapsulated paraffin waxes show little change in the latent heat of fusion and melting temperature after one thousand thermal recycles. Besides, the chemical characteristics and structural profile remained constant after one thousand thermal cycling tests. Therefore, microencapsulated paraffin wax/polyaniline is a stable material that can be used for thermal energy storage systems.
Exergaming for Individuals with Spinal Cord Injury: A Pilot Study

Mat Rosly M, Halaki M, Mat Rosly H, Cuesta V, Hasnan N, Davis GM, et al.

Games Health J, 2017 Oct;6(5):279-289.
PMID: 28968153 DOI: 10.1089/g4h.2017.0028

OBJECTIVE: Commercially available exergames that are for wheelchair-bound individuals with spinal cord injury (SCI) are scarce. This study sought to identify exergames for individuals with SCI that are "dose-potent" for health benefits.
MATERIALS AND METHODS: Six participants with SCI were recruited for a pilot study to investigate the exercise intensity of selected exergames (Move Tennis, Move Boxing, and Move Gladiator Duel) for the potential to improve health. Issues relating to exergaming for individuals with SCI were identified, and a Move Kayaking exergame was conceived using relevant design processes in an iterative manner. These processes included the following: participant needs and requirements, system requirements (hardware), system architecture (physical and operational views), and integration and verification of the finished system. Emphasis was given to operational and physical designs of the Move Kayaking exergame.
RESULTS: Move Boxing, Move Gladiator Duel, and Move Kayaking achieved moderate intensity exercise, while Move Tennis only achieved exercise of low intensity based on participants' metabolic equivalent. However, all four exergames achieved at least moderate intensity based on individuals' ratings of perceived exertion (RPE).
CONCLUSION: The intensity classification while playing Move Boxing, Move Tennis, Move Gladiator Duel, and Move Kayaking, using RPE, reported adequate exercise intensities prescribed by exercise guidelines.
Fulltext Exergaming boxing versus heavy-bag boxing: are these equipotent for individuals with spinal cord injury?

Mat Rosly M, Mat Rosly H, Hasnan N, Davis GM, Husain R

Eur J Phys Rehabil Med, 2017 Aug;53(4):527-534.
PMID: 28092144 DOI: 10.23736/S1973-9087.17.04456-2

BACKGROUND: Current strategies for increased physical activity and exercise in individuals with spinal cord injury (SCI) face many challenges with regards to maintaining their continuity of participation. Barriers cited often include problems with accessing facilities, mundane, monotonous or boring exercises and expensive equipment that is often not adapted for wheelchair users.
AIM: To compare the physiological responses and user preferences between conventional heavy-bag boxing against a novel form of video game boxing, known as exergaming boxing.
DESIGN: Cross-sectional study.
SETTING: Exercise laboratory setting in a university medical center.
POPULATION: Seventeen participants with SCI were recruited, of which sixteen were male and only one female. Their mean age was 35.6±10.2 years.
METHODS: All of them performed a 15-minute physical exercise session of exergaming and heavy-bag boxing in a sitting position. The study assessed physiological responses in terms of oxygen consumption, metabolic equivalent (MET) and energy expenditure between exergaming and heavy-bag boxing derived from open-circuit spirometry. Participants also rated their perceived exertion using Borg's category-ratio ratings of perceived exertion.
RESULTS: Both exergaming (MET: 4.3±1.0) and heavy-bag boxing (MET: 4.4±1.0) achieved moderate exercise intensities in these participants with SCI. Paired t-test revealed no significant differences (P>0.05, Cohen's d: 0.02-0.49) in the physiological or perceived exertional responses between the two modalities of boxing. Post session user survey reported all the participants found exergaming boxing more enjoyable.
CONCLUSIONS: Exergaming boxing, was able to produce equipotent physiological responses as conventional heavy-bag boxing. The intensity of both exercise modalities achieved recommended intensities for health and fitness benefits.
CLINICAL REHABILITATION IMPACT: Exergaming boxing have the potential to provide an enjoyable, self-competitive environment for moderate-vigorous exercise even at the comfort of their homes.
Leisure time physical activity participation in individuals with spinal cord injury in Malaysia: barriers to exercise

Mat Rosly M, Halaki M, Hasnan N, Mat Rosly H, Davis GM, Husain R

Spinal Cord, 2018 08;56(8):806-818.
PMID: 29410495 DOI: 10.1038/s41393-018-0068-0

STUDY DESIGN: Cross-sectional.
OBJECTIVES: An epidemiological study describing leisure time physical activities (LTPA) and the associations of barriers, sociodemographic and injury characteristics to moderate-vigorous aerobic exercise participation among individuals with spinal cord injury (SCI) in a developing Southeast Asian country.
SETTING: SCI community in Malaysia.
METHODS: The study sample consisted of 70 participants with SCI. Questionnaires were distributed containing an abbreviated Physical Activity Scale for Individuals with Physical Disabilities (items 2-6) and the Barriers to Exercise Scale using a 5-tier Likert format. Statistical analyses were χ2 tests, odds ratios, and binary forward stepwise logistic regression to assess the association and to predict factors related to participation in moderate-vigorous intensity aerobic exercise (items 4 and 5).
RESULTS: Seventy-three percent of the study sample did not participate in any form of moderate or vigorous LTPA. The top three barriers to undertaking LTPA (strongly agree and agree descriptors) were expensive exercise equipment (54%), pain (37%) and inaccessible facilities (36%). Participants over the age of 35 years, ethnicity, health concerns, perceiving exercise as difficult and indicating lack of transport were significantly different (p
A review of Acalypha indica L. (Euphorbiaceae) as traditional medicinal plant and its therapeutic potential

Zahidin NS, Saidin S, Zulkifli RM, Muhamad II, Ya'akob H, Nur H

J Ethnopharmacol, 2017 Jul 31;207:146-173.
PMID: 28647509 DOI: 10.1016/j.jep.2017.06.019

ETHNOPHARMACOLOGICAL RELEVANCE: Acalypha indica is an herbal plant that grows in wet, temperate and tropical region, primarily along the earth's equator line. This plant is considered by most people as a weed and can easily be found in these regions. Although this plant is a weed, Acalypha indica has been acknowledged by local people as a useful source of medicine for several therapeutic treatments. They consume parts of the plant for many therapeutics purposes such as anthelmintic, anti-ulcer, bronchitis, asthma, wound healing, anti-bacterial and other applications. As this review was being conducted, most of the reports related to ethnomedicinal practices were from Asian and African regions.
THE AIM OF THE REVIEW: The aim of this review is to summarize the current studies on ethnomedicinal practices, phytochemistry, pharmacological studies and a potential study of Acalypha indica in different locations around the world. This review updates related information regarding the potential therapeutic treatments and also discusses the toxicity issue of Acalypha indica.
MATERIALS AND METHODS: This review was performed through a systematic search related to Acalypha indica including the ethnomedicinal practices, phytochemistry and pharmacological studies around the world. The data was collected from online journals, magazines, and books, all of which were published in English, Malay and Indonesian. Search engine websites such as Google, Google Scholar, PubMed, Science Direct, Researchgate and other online collections were utilized in this review to obtain information.
RESULTS: The links between ethnomedicinal practices and scientific studies have been discussed with a fair justification. Several pharmacological properties exhibited certain potentials based on the obtained results that came from different related studies. Based on literature studies, Acalypha indica has the capability to serve as anthelmintic, anti-inflammation, anti-bacterial, anti-cancer, anti-diabetes, anti-hyperlipidemic, anti-obesity, anti-venom, hepatoprotective, hypoxia, and wound healing medicine. For the traditional practices, the authors also mentioned several benefits of consuming the raw plant and decoction.
CONCLUSION: This review summarizes the current studies of Acalypha indica collected from many regions. This review hopefully will provide a useful and basic knowledge platform for anyone interested in gaining information regarding Acalypha indica.
Fulltext Encountering Covid-19 and perceived stress and the role of a health climate among medical workers

Abbas S, Al-Abrrow H, Abdullah HO, Alnoor A, Khattak ZZ, Khaw KW

Curr Psychol, 2022;41(12):9109-9122.
PMID: 33519147 DOI: 10.1007/s12144-021-01381-8

Due to the outbreak of Covid-19 epidemic, work stress among health sector employees has risen too high. The study aims at determining the effect of the current coronavirus epidemic in the form of stress perceived among the medical workers in Pakistan and to discover the moderating role played by a healthy climate in offsetting it. The data was collected from 255 medical workers through a self-administered online questionnaire. Multiple Hierarchical Regression was used as a tool to test the hypotheses of the study. The results obtained indicate a correlation between the pandemic and the stress caused by it among the health workers, whereas, the role of a wholesome climate in the reduction of stress among them was found lacking. Sub-hypotheses indicate that the healthy environment provided by supervisors is effective in reducing the impact of workers' handling of the Covid-19 epidemic and perceived stress, while the healthy environment provided by hospitals in general or by workgroups fails to cause such positive change. This revelation necessitates the adoption of compulsory precautionary measures on the part of relevant authorities, because increase in stress caused by the pandemic can prove more lethal than the pandemic itself. The threat of the coronavirus pandemic has emerged as a massive socio-economic challenge for the global community, especially for the developing countries like Pakistan which faces serious socio-economic challenges in the current scenario. On account of the similarity of situations, the results obtained through this study can be safely generalized to other developing countries, particularly from the South Asian region.
A case of concurrent gastrointestinal, peritoneal and urinary bladder tuberculosis

Ahmad MF, Mohamad N, Sapiai NA, Razali NA, Anuar AH

Indian J Tuberc, 2022 Oct;69(4):706-709.
PMID: 36460413 DOI: 10.1016/j.ijtb.2021.09.004

Tuberculosis is a top 10 leading cause of death worldwide. Lungs are primarily involved organs in tuberculosis. The rest of cases are extrapulmonary tuberculosis (14% reported in 2017). Extrapulmonary tuberculosis always presents with non-specific symptoms, thus at risk of delay diagnosis and management. In genitourinary tuberculosis, kidney alone and kidney with urinary bladder or ureter is affected in more than 70% of cases. The ureter and urinary bladder infections are almost always secondary to tuberculous involvement of the kidney. Bacilli haematogenic spreading is a known transmission pathway to the kidney. In this case, we diagnosed isolated urinary bladder tuberculosis caused by direct gastrointestinal tuberculosis infiltration, a rare occurrence of extrapulmonary tuberculosis. We illustrate the multiorgan involvement in tuberculosis infection including pulmonary, gastrointestinal, peritoneal and urinary bladder.
Fulltext Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

Parham S, Kharazi AZ, Bakhsheshi-Rad HR, Nur H, Ismail AF, Sharif S, et al.

Antioxidants (Basel), 2020 Dec 21;9(12).
PMID: 33371338 DOI: 10.3390/antiox9121309

Recently, increasing public concern about hygiene has been driving many studies to investigate antimicrobial and antiviral agents. However, the use of any antimicrobial agents must be limited due to their possible toxic or harmful effects. In recent years, due to previous antibiotics' lesser side effects, the use of herbal materials instead of synthetic or chemical drugs is increasing. Herbal materials are found in medicines. Herbs can be used in the form of plant extracts or as their active components. Furthermore, most of the world's populations used herbal materials due to their strong antimicrobial properties and primary healthcare benefits. For example, herbs are an excellent material to replace nanosilver as an antibiotic and antiviral agent. The use of nanosilver involves an ROS-mediated mechanism that might lead to oxidative stress-related cancer, cytotoxicity, and heart diseases. Oxidative stress further leads to increased ROS production and also delays the cellular processes involved in wound healing. Therefore, existing antibiotic drugs can be replaced with biomaterials such as herbal medicine with high antimicrobial, antiviral, and antioxidant activity. This review paper highlights the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials. Antimicrobial activity, radical scavenger ability, the potential for antimicrobial, antiviral, and anticancer agents, and efficacy in eliminating bacteria and viruses and scavenging free radicals in herbal materials are discussed in this review. The presented herbal antimicrobial agents in this review include clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic, which are all summarized.
Prevalence of smartphone addiction and its associated factors among pre-clinical medical and dental students in a public university in Malaysia

Said AH, Mohd FN, Yusof MZ, Mohd Win NAN, Mazlan AN, Shaharudin AS

Malays Fam Physician, 2022 Nov 30;17(3):64-73.
PMID: 36606166 DOI: 10.51866/oa.75

INTRODUCTION: Smartphone addiction is becoming a global concern affecting every part of society, including healthcare professionals. This study aimed to identify the prevalence of risk of smartphone addiction and its associated factors among medical and dental students in a public university in Malaysia.
METHOD: This cross-sectional study was conducted among pre-clinical medical and dental students using convenience sampling. Questions regarding sociodemographic profile and responses to the Smartphone Addiction Scale Short Version (SAS-SV) and Depression, Anxiety and Stress Score questionnaire (DASS-21) were collected. Multiple logistic regression testing was used to analyse the factors associated with smartphone addiction.
RESULTS: We invited 409 pre-clinical medical and dental students to participate voluntarily, resulting in a response rate of 80.2%. The prevalence of high-risk smartphone addiction among the participants was 47.9%. Male participants, participants who used smartphones mainly for social media, and participants with depressive symptoms were more likely to have a high risk of smartphone addiction. Medical students, participants who spent less than 3 hours per day on a smartphone, and participants who used smartphones for education-related activities were less likely to have a high risk of smartphone addiction.
CONCLUSION: Smartphone addiction prevalence among pre-clinical medical and dental students was high. Therefore, the authorities should overcome this problem by implementing early measures.
Fulltext Computation and memory optimized spectral domain convolutional neural network for throughput and energy-efficient inference

Rizvi SM, Rahman AAA, Sheikh UU, Fuad KAA, Shehzad HMF

Appl Intell (Dordr), 2023;53(4):4499-4523.
PMID: 35730044 DOI: 10.1007/s10489-022-03756-1

Conventional convolutional neural networks (CNNs) present a high computational workload and memory access cost (CMC). Spectral domain CNNs (SpCNNs) offer a computationally efficient approach to compute CNN training and inference. This paper investigates CMC of SpCNNs and its contributing components analytically and then proposes a methodology to optimize CMC, under three strategies, to enhance inference performance. In this methodology, output feature map (OFM) size, OFM depth or both are progressively reduced under an accuracy constraint to compute performance-optimized CNN inference. Before conducting training or testing, it can provide designers guidelines and preliminary insights regarding techniques for optimum performance, least degradation in accuracy and a balanced performance-accuracy trade-off. This methodology was evaluated on MNIST and Fashion MNIST datasets using LeNet-5 and AlexNet architectures. When compared to state-of-the-art SpCNN models, LeNet-5 achieves up to 4.2× (batch inference) and 4.1× (single-image inference) higher throughputs and 10.5× (batch inference) and 4.2× (single-image inference) greater energy efficiency at a maximum loss of 3% in test accuracy. When compared to the baseline model used in this study, AlexNet delivers 11.6× (batch inference) and 5× (single-image inference) increased throughput and 25× (batch inference) and 8.8× (single-image inference) more energy-efficient inference with just 4.4% reduction in accuracy.
Fulltext The Effect of Dataset Imbalance on the Performance of SCADA Intrusion Detection Systems

Balla A, Habaebi MH, Elsheikh EAA, Islam MR, Suliman FM

Sensors (Basel), 2023 Jan 09;23(2).
PMID: 36679553 DOI: 10.3390/s23020758

Integrating IoT devices in SCADA systems has provided efficient and improved data collection and transmission technologies. This enhancement comes with significant security challenges, exposing traditionally isolated systems to the public internet. Effective and highly reliable security devices, such as intrusion detection system (IDSs) and intrusion prevention systems (IPS), are critical. Countless studies used deep learning algorithms to design an efficient IDS; however, the fundamental issue of imbalanced datasets was not fully addressed. In our research, we examined the impact of data imbalance on developing an effective SCADA-based IDS. To investigate the impact of various data balancing techniques, we chose two unbalanced datasets, the Morris power dataset, and CICIDS2017 dataset, including random sampling, one-sided selection (OSS), near-miss, SMOTE, and ADASYN. For binary classification, convolutional neural networks were coupled with long short-term memory (CNN-LSTM). The system's effectiveness was determined by the confusion matrix, which includes evaluation metrics, such as accuracy, precision, detection rate, and F1-score. Four experiments on the two datasets demonstrate the impact of the data imbalance. This research aims to help security researchers in understanding imbalanced datasets and their impact on DL SCADA-IDS.
Oil palm (Elaeis guineensis) plantation on tropical peatland in South East Asia: Photosynthetic response to soil drainage level for mitigation of soil carbon emissions

McCalmont J, Kho LK, Teh YA, Chocholek M, Rumpang E, Rowland L, et al.

Sci Total Environ, 2023 Feb 01;858(Pt 1):159356.
PMID: 36270353 DOI: 10.1016/j.scitotenv.2022.159356

While existing moratoria in Indonesia and Malaysia should preclude continued large-scale expansion of palm oil production into new areas of South-East Asian tropical peatland, existing plantations in the region remain a globally significant source of atmospheric carbon due to drainage driven decomposition of peatland soils. Previous studies have made clear the direct link between drainage depth and peat carbon decomposition and significant reductions in the emission rate of CO2 can be made by raising water tables nearer to the soil surface. However, the impact of such changes on palm fruit yield is not well understood and will be a critical consideration for plantation managers. Here we take advantage of very high frequency, long-term monitoring of canopy-scale carbon exchange at a mature oil palm plantation in Malaysian Borneo to investigate the relationship between drainage level and photosynthetic uptake and consider the confounding effects of light quality and atmospheric vapour pressure deficit. Canopy modelling from our dataset demonstrated that palms were exerting significantly greater stomatal control at deeper water table depths (WTD) and the optimum WTD for photosynthesis was found to be between 0.3 and 0.4 m below the soil surface. Raising WTD to this level, from the industry typical drainage level of 0.6 m, could increase photosynthetic uptake by 3.6 % and reduce soil surface emission of CO2 by 11 %. Our study site further showed that despite being poorly drained compared to other planting blocks at the same plantation, monthly fruit bunch yield was, on average, 14 % greater. While these results are encouraging, and at least suggest that raising WTD closer to the soil surface to reduce emissions is unlikely to produce significant yield penalties, our results are limited to a single study site and more work is urgently needed to confirm these results at other plantations.
Fulltext Clinical Audit on Badminton-Related Ocular Injuries in a Tertiary Hospital in Malaysia

Mohd Rasidin AH, Muhammad-Ikmal MK, Raja Omar RN, Yaakub A, Ahmad Tajudin LS

Cureus, 2022 Oct;14(10):e30769.
PMID: 36447729 DOI: 10.7759/cureus.30769

Background Badminton-related ocular injuries are among the commonest causes of blunt trauma to the eye, which can lead to significant damage to the ocular structures. This study aimed to assess the clinical presentations, complications, and visual outcomes of patients who sustained ocular injuries related to badminton treated in a single tertiary center in Malaysia. Materials and methods A retrospective clinical audit was conducted in Hospital Universiti Sains Malaysia (HUSM), Malaysia, involving patients diagnosed with ocular injuries related to badminton, either as players or spectators, between January 1, 2003 and December 31, 2017. The demographic data, mechanism of injury, and clinical presentation were recorded. In addition, visual acuity, anterior and posterior segment, and intraocular pressure (IOP) measurements were recorded at the initial presentation and at the present recruitment period. Management at the initial presentation was also obtained and recorded. The final visual outcome and complications were based on the finding of the most recent follow-up. Visual acuity was categorized as follows: mild or no visual impairment (6/18 or better), moderate and severe visual impairment (<6/18 and worse). Results A total of 23 patients (23 eyes) were included in this clinical audit. The average age was 24 years, with a range of 6-56 years, with the highest incidence occurring at the age of 20 years old and younger. The majority of the injuries were sustained during the single-player game. All the injuries were caused by shuttlecock hits. In 18 cases (78%), the trauma was caused by an opponent, in four cases (17%) by a partner, and in one case involving a bystander. Most of the patients in this series were not using any protective eyewear while playing the game 96% (22). Most injuries (22 eyes) involved the anterior segment, with hyphaema as the commonest clinical presentation. The mean IOP at presentation was 23.5 (11.2) mmHg. Angle recession was detected as early as one-week post initial presentation in 17 eyes. Commotio retinae (5 eyes) and vitreous hemorrhage (4 eyes) were the common posterior segment findings. There were eight eyes with visual acuity of worse than 6/18 at the initial presentation, but only three eyes had poor final visual acuity. There was a statistically significant improvement in visual acuity at the last follow-up compared to the initial presentation (Fisher's exact test) (p=0.032). Conclusion Ocular injuries related to badminton is common and cause a detrimental effect on the long-term visual outcome. Traumatic hyphaema and commotio retinae are the most common presenting signs related to poor visual outcomes. Therefore, protective eyewear and promoting awareness of badminton-related ocular injuries are essential to prevent monocular blindness in young adults.
Novel magnetic graphene oxide functionalized cyanopropyl nanocomposite as an adsorbent for the removal of Pb(II) ions from aqueous media: equilibrium and kinetic studies

Gabris MA, Jume BH, Rezaali M, Shahabuddin S, Nodeh HR, Saidur R

Environ Sci Pollut Res Int, 2018 Sep;25(27):27122-27132.
PMID: 30022389 DOI: 10.1007/s11356-018-2749-9

This work presents the synthesis of the novel silica-cyanopropyl functionalized magnetic graphene oxide (MGO/SiO2-CN) hybrid nanomaterial derived by sol-gel method as a cheap efficient magnetic sorbent for the removal of extremely hazardous lead ions from aqueous media. The integration of the magnetic property, the carbon substrate, and the nitrile (-C ≡ N) containing organic grafted silica matrix promoted the adsorption capability against lead ions along with its simple synthesis recovery and low cost. The prepared nanocomposite was comprehensively characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. Adsorption of lead was found to be pH dependent because of the charged nature of both analyte and adsorbent surface. Adsorption experiments were conducted under the optimum conditions, and the obtained experimental data from atomic absorption spectroscopy were analyzed using the popular isothermal models namely Langmuir, Freundlich, and Dubinin-Radushkevich isotherms as well as kinetically studied and evaluated for adsorption standard free energy (E). The experimental results have demonstrated the enhanced adsorption capability of the proposed sorbent nanocomposite for lead ion removal with the maximum adsorption capacity of 111.11 mg/g at pH 5.0. The proposed mechanism of lead adsorption was mainly attributed to the complexation of lead positive ions with the grafted -C ≡ N bond. The synergistic effect of the combination of three components (i.e., the magnetic graphene oxide matrix, the triple bond containing organic moiety, and the inorganic porous silica framework) excelled the adsorption capability and proved to be a good candidate as adsorbent for the removal of lead ions.
Risk analysis of inhaled hexavalent chromium (Cr6+) exposure on blacksmiths from industrial area

Oginawati K, Susetyo SH, Rosalyn FA, Kurniawan SB, Abdullah SRS

Environ Sci Pollut Res Int, 2021 Mar;28(11):14000-14008.
PMID: 33201502 DOI: 10.1007/s11356-020-11590-6

Chromium (Cr) is used as a mixture to improve strength and corrosion resistance. Milling and welding processes can expose workers to Cr through dermal exposure and inhalation. Cr exposure can be determined by urine testing. The purpose of this study was to analyze the concentration of Cr in urine (UCr) of workers. This study was carried out using a cross-sectional method. Sampling was conducted in the village of Mekarmaju, Bandung, Indonesia. The number of respondents included 30 blacksmiths, and the control group comprised 10 people who were not blacksmiths. Cr6+ exposure was measured using a personal sampling pump placed on the collar of the worker's shirt as a breathing zone and then analyzed using a UV-visible spectrophotometer. UCr was measured with a graphite furnace atomic absorption spectrophotometer. The measured Cr6+ concentration in the exposed working area ranged from 0.03 to 0.63 mg/m3, whereas that in non-exposed area ranged from 0.02 to 0.04 mg/m3. Results showed that 16 out of 30 blacksmiths had a UCr concentration above the biological exposure index (BEI) value, 21 had a higher value than the threshold limit value (TLV), and 22 had hazard index (HI) values > 1, which indicated that Cr has a hazardous potential in the body. The analysis of the exposed and control groups showed a significant difference with a p value of 0.000 for TLV, chronic daily intake, and UCr. These results clearly showed that Cr6+ exposure may harm the health of these workers in the future. The results obtained in this study can be used to promote workers' awareness on the potential health risk caused by Cr6+ exposure in the working environment.
Big Data Analytics Using Cloud Computing Based Frameworks for Power Management Systems: Status, Constraints, and Future Recommendations

Al-Jumaili AHA, Muniyandi RC, Hasan MK, Paw JKS, Singh MJ

Sensors (Basel), 2023 Mar 08;23(6).
PMID: 36991663 DOI: 10.3390/s23062952

Traditional parallel computing for power management systems has prime challenges such as execution time, computational complexity, and efficiency like process time and delays in power system condition monitoring, particularly consumer power consumption, weather data, and power generation for detecting and predicting data mining in the centralized parallel processing and diagnosis. Due to these constraints, data management has become a critical research consideration and bottleneck. To cope with these constraints, cloud computing-based methodologies have been introduced for managing data efficiently in power management systems. This paper reviews the concept of cloud computing architecture that can meet the multi-level real-time requirements to improve monitoring and performance which is designed for different application scenarios for power system monitoring. Then, cloud computing solutions are discussed under the background of big data, and emerging parallel programming models such as Hadoop, Spark, and Storm are briefly described to analyze the advancement, constraints, and innovations. The key performance metrics of cloud computing applications such as core data sampling, modeling, and analyzing the competitiveness of big data was modeled by applying related hypotheses. Finally, it introduces a new design concept with cloud computing and eventually some recommendations focusing on cloud computing infrastructure, and methods for managing real-time big data in the power management system that solve the data mining challenges.
Fulltext Elucidating the alkene hydrogenation reaction based on cotton textile reduced graphene oxide under the influence of external electric field: Illustration of new noble method

Amer GE, Razak FIA, Sapari S, Nur H, Setu SA

Heliyon, 2023 Apr;9(4):e14888.
PMID: 37025917 DOI: 10.1016/j.heliyon.2023.e14888

The hydrogenation reaction of alkene is one of the most used industrial chemical process for various materials of daily life and energy consumption. This is a heterogeneous reaction and traditionally carried out by metallic catalysis. However, these conventional catalytic hydrogenations of alkene suffer from various setbacks such as catalyst poisoning, less recyclability and are environmentally unfriendly. Therefore, in recent years, researchers have been trying to develop the alternatives to metal catalysis hydrogenation of alkene. Heterogeneous catalysis under the external electric field is considered the future of green catalysis. In this paper, we report a comprehensive investigation dealing with the theoretical basis for simulating the phenomenon of heterogeneous catalysis, on a molecular level, under an external electric field. The illustration of the prospect as well as the effects of the mostly used catalytic systems, reduced graphene oxide, under the influence of external electric fields is provided. Moreover, a noble method of alkene hydrogenation reaction based on cotton textile reduced graphene oxide (CT-RGO) under the influence of an external electric field is introduced. The corresponding theoretical investigation was carried out within the framework of the density functional theory (DFT) method using first-principles calculations. The study has been carried out by elucidating DFT calculations for three different proposed catalytic systems, namely without electricity, with electricity and with an external electric field of 2 milli-Atomic unit. The obtained results indicate that adsorption energy of H2 on the CT-RGO surface is significantly higher when the electric field is applied along the bond axis, suggesting thereby that hydrogenation of alkene can be induced with CT-RGO catalyst support under external electric fields. The obtained results shed light on the effect of the external electricity field on the graphene-hydrogen complex, the activation energy of graphene radicals to achieve the transition states as well as the adsorption of the hydrogen atoms over the graphene surface. Altogether, the theoretical results presented herein suggested that the proposed catalytic system holds promise for facilitating the alkene hydrogenation under external electric fields.
Fulltext Distribution of organochlorine pesticide pollution in water, sediment, mollusk, and fish at Saguling Dam, West Java, Indonesia

Oginawati K, Susetyo SH, Rahmawati SI, Kurniawan SB, Abdullah SRS

Toxicol Res, 2022 Apr;38(2):149-157.
PMID: 35419272 DOI: 10.1007/s43188-021-00094-1

This study aims to determine the distribution of organochlorine pesticide pollution in water, sediments, mollusks, and fish at Saguling Dam as baseline data of organochlorine pollution. Samples were obtained from 12 locations, with 9 and 3 sampling points inside and outside the dam, respectively. Measurement of organochlorine residues was carried out using methods of extraction, purification, evaporation, and gas chromatography. Results showed the presence of several types of organochlorine compounds, namely, lindane, aldrin, dieldrin, heptachlor, dichlorodiphenyltrichloroethane (DDT), and endosulfan. Aldrin was dominant in water (2-37 μg/L) and sediments (2-1438 μg/L), while DDT and heptachlor were dominant organochlorine compounds in mollusks (13-2758 µg/L) and fish (11-104 μg/L), respectively. Sediments demonstrated higher organochlorine concentrations than water, mollusk, and fish. The distribution of organochlorine was affected by land use around the Citarum watershed and pollutant input from tributaries.
Fulltext Service availability and readiness of malaria surveillance information systems implementation at primary health centers in Indonesia

Herawati MH, Besral, Lolong DB, Pracoyo NE, Sukoco NEW, Supratikta H, et al.

PLoS One, 2023;18(4):e0284162.
PMID: 37104477 DOI: 10.1371/journal.pone.0284162

One of the most important indicators in malaria eradication is the malaria surveillance information system (SISMAL) for recording and reporting medical cases. This paper aims to describe the availability and readiness of SISMALs at primary health centers (PHCs) in Indonesia. A cross-sectional survey was implemented in seven provinces for this study. The data was analyzed using bivariate, multivariate, and linear regression. The availability of the information system was measured by assessing the presence of the electronic malaria surveillance information system (E-SISMAL) at the studied PHCs. The readiness was measured by averaging each component of the assessment. From 400 PHC samples, only 58.5% had available SISMALs, and their level of readiness was only 50.2%. Three components had very low levels of readiness: (1) the availability of personnel (40.9%), (2) SISMAL integration and storage (50.2%), and (3) the availability of data sources and indicators (56.8%). Remote and border (DTPK) areas had a 4% better readiness score than non-DTPK areas. Endemic areas were 1.4% better than elimination areas, while regions with low financial capacity were 3.78% better than regions with high financial capacity, with moderate capacity (2.91%). The availability rate of the SISMAL at PHCs is only 58.5%. Many PHCs still do not have SISMALs. The readiness of the SISMAL at these PHCs is significantly related to DTPK/remote area, high endemicity status, and low financial capacity. This study found that the implementation of SISMAL is more accessible to malaria surveillance for the remote area and regions with low financial capacity. Therefore, this effort will well-fit to address barrier to malaria surveillance in developing countries.
Fulltext The Cytotoxic Activity of Dammarane-Type Triterpenoids Isolated from the Stem Bark of Aglaia cucullata (Meliaceae)

Purnama, Farabi K, Runadi D, Kuncoro H, Harneti D, Nurlelasari, et al.

Molecules, 2023 Jun 23;28(13).
PMID: 37446608 DOI: 10.3390/molecules28134946

The Aglaia genus, a member of the Meliaceae family, is generally recognized to include a number of secondary metabolite compounds with diverse structures and biological activities, including triterpenoids. Among the members of this genus, Aglaia cucullata has been reported to have unique properties and thrives exclusively in mangrove ecosystems. This plant is also known to contain various metabolites, such as flavaglines, bisamides, and diterpenoids, but there are limited reports on the isolation of triterpenoid compounds from its stem bark. Therefore, this research attempted to isolate and elucidate seven triterpenoids belonging to dammarane-type (1-7) from the stem bark of Aglaia cucullata. The isolated compounds included 20S,24S-epoxy-3α,25-dihydroxy-dammarane (1), dammaradienone (2), 20S-hydroxy-dammar-24-en-3-on (3), eichlerianic acid (4), (20S,24RS)-23,24-epoxy-24-methoxy-25,26,27-tris-nor dammar-3-one (5), 3α-acetyl-cabraleahydroxy lactone (6), and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (7). Employing spectroscopic techniques, the chemical structures of the triterpenoids were identified using FTIR, NMR, and HRESITOF-MS. The cytotoxic activity of compounds 1-7 was tested with the PrestoBlue cell viability reagent against MCF-7 breast cancer, B16-F10 melanoma, and CV-1 normal kidney fibroblast cell lines. The results displayed that compound 5 had the highest level of bioactivity compared to the others. Furthermore, the IC50 values obtained were more than 100 μM, indicating the low potential of natural dammarane-type triterpenoids as anticancer agents. These findings provided opportunities for further studies aiming to increase their cytotoxic activities through semi-synthetic methods.

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