Displaying publications 21 - 40 of 48 in total

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  1. Mitigation of indoor air pollution: A review of recent advances in adsorption materials and catalytic oxidation
    Yue X, Ma NL, Sonne C, Guan R, Lam SS, Van Le Q, et al.
    J Hazard Mater, 2021 03 05;405:124138.
    PMID: 33092884 DOI: 10.1016/j.jhazmat.2020.124138
    Indoor air pollution with toxic volatile organic compounds (VOCs) and fine particulate matter (PM2.5) is a threat to human health, causing cancer, leukemia, fetal malformation, and abortion. Therefore, the development of technologies to mitigate indoor air pollution is important to avoid adverse effects. Adsorption and photocatalytic oxidation are the current approaches for the removal of VOCs and PM2.5 with high efficiency. In this review we focus on the recent development of indoor air pollution mitigation materials based on adsorption and photocatalytic decomposition. First, we review on the primary indoor air pollutants including formaldehyde, benzene compounds, PM2.5, flame retardants, and plasticizer: Next, the recent advances in the use of adsorption materials including traditional biochar and MOF (metal-organic frameworks) as the new emerging porous materials for VOCs absorption is reviewed. We review the mechanism for mitigation of VOCs using biochar (noncarbonized organic matter partition and adsorption) and MOF together with parameters that affect indoor air pollution removal efficiency based on current mitigation approaches including the mitigation of VOCs using photocatalytic oxidation. Finally, we bring forward perspectives and directions for the development of indoor air mitigation technologies.
  2. A recent global review of hazardous chlorpyrifos pesticide in fruit and vegetables: Prevalence, remediation and actions needed
    Foong SY, Ma NL, Lam SS, Peng W, Low F, Lee BHK, et al.
    J Hazard Mater, 2020 Dec 05;400:123006.
    PMID: 32947729 DOI: 10.1016/j.jhazmat.2020.123006
    Pollution with pesticides is a widespread global problem and biomonitoring of the environment and human populations is necessary to assess potential harmful biological effects. One of the pesticides that are showing up in vegetables and fruit is chlorpyrifos (CPS). CPS is a nerve-poisoning organophosphorus insecticide, which is in up to 1/3 of all conventionally produced citrus fruits. Our review shows that CPS is a hazardous material that poses risks to human health and also pollutes the environment. There is numerous risk assessment of CPS reported, however, the assessment is easily affected by factors such as climate change, exposure period and CPS concentration. Therefore, rigorous update of the hazardous level of CPS is needed to determine the threshold level safe for humans and animals. There is a need for remediation using for example photoreactive nanoparticle methods and microbial degeneration possessing high degradation efficiency (73-97%). In addition, stringent biomonitoring of food, environment and human exposure should occur to avoid exposure to chemicals via citrus fruits and vegetables. This is necessary to assess health risks and socioeconomic impacts which also require collaboration between private and public sectors to facilitate the growth, sale and manufacturing of biopesticides.
  3. Innovative hydrolysis of corn stover biowaste by modified magnetite laccase immobilized nanoparticles
    Gou Z, Ma NL, Zhang W, Lei Z, Su Y, Sun C, et al.
    Environ Res, 2020 09;188:109829.
    PMID: 32798948 DOI: 10.1016/j.envres.2020.109829
    Intensive studies have been performed on the improvement of bioethanol production by transformation of lignocellulose biomass. In this study, the digestibility of corn stover was dramatically improved by using laccase immobilized on Cu2+ modified recyclable magnetite nanoparticles, Fe3O4-NH2. After digestion, the laccase was efficiently separated from slurry. The degradation rate of lignin reached 40.76%, and the subsequent cellulose conversion rate 38.37% for 72 h at 35 °C with cellulase at 50 U g-1 of corn stover. Compared to those of free and inactivated mode, the immobilized laccase pre-treatment increased subsequent cellulose conversion rates by 23.98% and 23.34%, respectively. Moreover, the reusability of immobilized laccase activity remained 50% after 6 cycles. The storage and thermal stability of the fixed laccase enhanced by 70% and 24.1% compared to those of free laccase at 65 °C, pH 4.5, respectively. At pH 10.5, it exhibited 16.3% more activities than its free mode at 35 °C. Our study provides a new avenue for improving the production of bioethanol with immobilized laccase for delignification using corn stover as the starting material.
  4. Fulltext Covid-19 pandemic in the lens of food safety and security
    Ma NL, Peng W, Soon CF, Noor Hassim MF, Misbah S, Rahmat Z, et al.
    Environ Res, 2021 Feb;193:110405.
    PMID: 33130165 DOI: 10.1016/j.envres.2020.110405
    The recently emerged coronavirus disease (COVID-19), which has been characterised as a pandemic by the World Health Organization (WHO), is impacting all parts of human society including agriculture, manufacturing, and tertiary sectors involving all service provision industries. This paper aims to give an overview of potential host reservoirs that could cause pandemic outbreak caused by zoonotic transmission. Amongst all, continues surveillance in slaughterhouse for possible pathogens transmission is needed to prevent next pandemic outbreak. This paper also summarizes the potential threats of pandemic to agriculture and aquaculture sector that control almost the total food supply chain and market. The history lesson from the past, emerging and reemerging infectious disease including the Severe Acute Respiratory Syndrome (SARS) in 2002, Influenza A H1N1 (swine flu) in 2009, Middle East Respiratory Syndrome (MERS) in 2012 and the recent COVID-19 should give us some clue to improve especially the governance to be more ready for next coming pandemic.
  5. Phytoremediation of radionuclides in soil, sediments and water
    Yan L, Le QV, Sonne C, Yang Y, Yang H, Gu H, et al.
    J Hazard Mater, 2021 04 05;407:124771.
    PMID: 33388721 DOI: 10.1016/j.jhazmat.2020.124771
    Soil and water contaminated with radionuclides threaten the environment and public health during leaks from nuclear power plants. Remediation of radionuclides at the contaminated sites uses mainly physical and chemical methods such as vitrification, chemical immobilization, electro-kinetic remediation and soil excavation, capping and washing being among the preferred methods. These traditional technologies are however costly and less suitable for dealing with large-area pollution. In contrast to this, cost-effective and environment-friendly alternatives such as phytoremediation using plants to remove radionuclides from polluted sites in situ represent promising alternatives for environmental cleanup. Understanding the physiology and molecular mechanisms of radionuclides accumulation in plants is essential to optimize and improve this new remediation technology. Here, we give an overview of radionuclide contamination in the environment and biochemical characteristics for uptake, transport, and compartmentation of radionuclides in plants that characterize phytoextraction and its efficiency. Phytoextraction is an eco-friendly and efficient method for environmental removal of radionuclides at contaminated sites such as mine tailings. Selecting the most proper plant for the specific purpose, however, is important to obtain the best result together with, for example, applying soil amendments such as citric acid. In addition, using genetic engineering and optimizing agronomic management practices including regulation of atmospheric CO2 concentration, reasonable measures of fertilization and rational water management are important as well. For future application, the technique needs commercialization in order to fully exploit the technique at mining activities and nuclear industries.
  6. Improving sustainability and mitigating environmental impacts of agro-biowaste compost fertilizer by pelletizing-drying
    Sarlaki E, Kermani AM, Kianmehr MH, Asefpour Vakilian K, Hosseinzadeh-Bandbafha H, Ma NL, et al.
    Environ Pollut, 2021 Sep 15;285:117412.
    PMID: 34051566 DOI: 10.1016/j.envpol.2021.117412
    The use of agro-biowaste compost fertilizers in agriculture is beneficial from technical, financial, and environmental perspectives. Nevertheless, the physical, mechanical, and agronomical attributes of agro-biowaste compost fertilizers should be engineered to reduce their storage, handling, and utilization costs and environmental impacts. Pelletizing and drying are promising techniques to achieve these goals. In the present work, the effects of process parameters, including compost particle size/moisture content, pelletizing compression ratio, and drying air temperature/velocity, were investigated on the density, specific crushing energy, and moisture diffusion of agro-biowaste compost pellet. The Taguchi technique was applied to understand the effects of independent parameters on the output responses, while the optimal pellet properties were found using the iterative thresholding method. The soil and plant (sweet basil) response to the optimal biocompost pellet was experimentally evaluated. The farm application of the optimal pellet was also compared with the untreated agro-biowaste compost using the life cycle assessment approach to investigate the potential environmental impact mitigation of the pelletizing and drying processes. Generally, the compost moisture content was the most influential factor on the density and specific crushing energy of the dried pellet, while the moisture diffusion of the wet pellet during the drying process was significantly influenced by the pelletizing compression ratio. The density, specific crushing energy, and moisture diffusion of agro-biowaste compost pellet at the optimal conditions were 1242.49 kg/m3, 0.5054 MJ/t, and 8.2 × 10-8 m2/s, respectively. The optimal biocompost pellet could release 80% of its nitrogen content evenly over 98 days, while this value was 28 days for the chemical urea fertilizer. Besides, the optimal pellet could significantly improve the agronomical attributes of the sweet basil plant compared with the untreated biocompost. The applied strategy could collectively mitigate the weighted environmental impact of farm application of the agro-biowaste compost by more than 63%. This reduction could be attributed to the fact that the pelletizing-drying processes could avoid methane emissions from the untreated agro-biowaste compost during the farm application. Overall, pelletizing-drying of the agro-biowaste compost could be regarded as a promising strategy to improve the environmental and agronomical performance of farm application of organic biofertilizers.
  7. Microwave pyrolysis valorization of used baby diaper
    Lam SS, Wan Mahari WA, Ma NL, Azwar E, Kwon EE, Peng W, et al.
    Chemosphere, 2019 Sep;230:294-302.
    PMID: 31108440 DOI: 10.1016/j.chemosphere.2019.05.054
    Used baby diaper consists of a combination of decomposable cellulose, non-biodegradable plastic materials (e.g. polyolefins) and super-absorbent polymer materials, thus making it difficult to be sorted and separated for recycling. Microwave pyrolysis was examined for its potential as an approach to transform used baby diapers into value-added products. Influence of the key operating parameters comprising process temperature and microwave power were investigated. The pyrolysis showed a rapid heating process (up to 43 °C/min of heating rate) and quick reaction time (20-40 min) in valorizing the used diapers to generate pyrolysis products comprising up to 43 wt% production of liquid oil, 29 wt% gases and 28 wt% char product. Microwave power and operating temperature were observed to have impacts on the heating rate, process time, production and characteristics of the liquid oil and solid char. The liquid oil contained alkanes, alkenes and esters that can potentially be used as chemical additives, cosmetic products and fuel. The solid char contained high carbon, low nitrogen and free of sulphur, thus showing potential for use as adsorbents and soil additives. These observations demonstrate that microwave pyrolysis has great prospect in transforming used baby diaper into liquid oil and char products that can be utilised in several applications.
  8. Omics technologies used in pesticide residue detection and mitigation in crop
    Goh MS, Lam SD, Yang Y, Naqiuddin M, Addis SNK, Yong WTL, et al.
    J Hazard Mater, 2021 10 15;420:126624.
    PMID: 34329083 DOI: 10.1016/j.jhazmat.2021.126624
    In agriculture, the convenience and efficacy of chemical pesticides have become inevitable to manage cultivated crop production. Here, we review the worldwide use of pesticides based on their categories, mode of actions and toxicity. Excessive use of pesticides may lead to hazardous pesticide residues in crops, causing adverse effects on human health and the environment. A wide range of high-tech-analytical methods are available to analyse pesticide residues. However, they are mostly time-consuming and inconvenient for on-site detection, calling for the development of biosensors that detect cellular changes in crops. Such new detection methods that combine biological and physicochemical knowledge may overcome the shortage in current farming to develop sustainable systems that support environmental and human health. This review also comprehensively compiles domestic pesticide residues removal tips from vegetables and fruits. Synthetic pesticide alternatives such as biopesticide and nanopesticide are greener to the environment. However, its safety assessment for large-scale application needs careful evaluation. Lastly, we strongly call for reversions of pesticide application trends based on the changing climate, which is lacking in the current scenario.
  9. Zero waste multistage utilization of Ginkgo biloba branches
    Ma J, Ma NL, Zhang D, Wu N, Liu X, Meng L, et al.
    Chemosphere, 2022 Apr;292:133345.
    PMID: 34922964 DOI: 10.1016/j.chemosphere.2021.133345
    Zero waste multistage utilization of biomass from Ginkgo biloba branches (GBBs) was achieved through extraction of bioactive components, analysis of antioxidant and antibacterial activities, preparation and composition of pyrolyzate, adsorption and reuse of modified biochar. The results showed that GBBs had abundant bioactive components for potential application in the industry of food, chemical raw materials and biomedicine. Especially, the bioactive compounds in acetone extract (10 mg/mL) of GBBs identified by DPPH and ABTS had free radical scavenging abilities of 92.28% and 98.18%, respectively, which are equivalent to Vitamin C used as an antioxidant in food additives. Fourier Transform Infrared and X-Ray Diffraction analysis showed that carboxymethyl cellulose (CMC) and magnetic Fe3O4 were successfully incorporated into raw biochar (RB) to form CMC-Fe3O4-RB nanomaterial. Scanning electron microscopy and X-Ray Diffraction spectroscopy displayed Fe, C, and O existed on the surface of CMC-Fe3O4-RB. Compared with RB, CMC-Fe3O4-RB had a larger specific surface area, pore volume and pore size. Meanwhile, nanomagnetic CMC-Fe3O4-RB solved the problem of agglomeration in traditional magnetized biochar production, and improved the adsorption capacity of Pb2+, which was 29.90% higher than that of RB by ICP-OES. Further, the Pb2+ (10 mg/L) adsorption capacity of CMC-Fe3O4-RB reached the highest level in 2 h at the dosage of 0.01 g/L, and remained stable at 52.987 mg/g after five cycles of adsorption and desorption. This research aided in the creation of a strategy for GBBs zero waste multistage usage and a circular economic model for GBBs industry development, which can be promoted and applied to the fields of food industry and environment improvement.
  10. Synthesis, Molecular Docking and Biological Activity Evaluation of Alkoxy Substituted Chalcone Derivatives: Potential Apoptosis Inducing Agent on MCF-7 Cells
    Khairul WM, Hashim F, Mohammed M, Shah NSMN, Johari SATT, Rahamathullah R, et al.
    Anticancer Agents Med Chem, 2021;21(13):1738-1750.
    PMID: 33176667 DOI: 10.2174/1871520620999201110190709
    INTRODUCTION: In this contribution, a series of alkoxy substituted chalcones were successfully designed, synthesized, spectroscopically characterized and evaluated for their cytotoxicity potential in inhibiting the growth of MCF-7 cells.

    OBJECTIVE: In order to investigate the influence between electron density in conjugated π-systems and biological activities, different withdrawing substituents, namely Nitro (NO2), Cyano (C≡N) and trifluoromethyl (CF3) were introduced in the chalcone-based molecular system.

    METHODS: All the derivatives were then tested on MCF-7 cell line using the fluorescence microscopy-based cytotoxicity analyses.

    RESULTS: The preliminary findings showed that both -NO2 and -CF3 substituents revealed their potential to inhibit the growth of MCF-7 with IC;50 values of 14.75 and 13.75 μg/ml, respectively. In addition, the morphological changes of MCF-7 cells were observed in response to alkoxy substituted chalcone treatment through an induction of apoptosis pathway with cell blebbing, phosphatidylserine exposure and autophagic activity with acidification of lysosomal structure. Intermolecular interaction based on in silico investigation on nitro, trifluoromethyl and cyano based chalcones exhibited several types of interactions with tumor necrosis factor receptor (PDB: 1EXT) protein and high hydrogen bond in the molecule-receptor interaction have given significant impact towards their toxicity on MCF-7 cells.

    CONCLUSION: Significantly, these types of chalcones exhibited ideal and high potential to be further developed as anti-cancer agents.

  11. Production of bio-fertilizer from microwave vacuum pyrolysis of palm kernel shell for cultivation of Oyster mushroom (Pleurotus ostreatus)
    Nam WL, Phang XY, Su MH, Liew RK, Ma NL, Rosli MHNB, et al.
    Sci Total Environ, 2018 May 15;624:9-16.
    PMID: 29245037 DOI: 10.1016/j.scitotenv.2017.12.108
    Microwave vacuum pyrolysis of palm kernel shell (PKS) was performed to produce biochar, which was then tested as bio-fertilizer in growing Oyster mushroom (Pleurotus ostreatus). The pyrolysis approach produced biochar containing a highly porous structure with a high BET surface area of up to 270m2/g and low moisture content (≤10wt%), exhibiting desirable adsorption properties to be used as bio-fertilizer since it can act as a housing that provides many sites on which living microorganisms (mycelium or plant-growth promoting bacteria) and organic nutrients can be attached or adsorbed onto. This could in turn stimulate plant growth by increasing the availability and supply of nutrients to the targeted host plant. The results from growing Oyster mushroom using the biochar recorded an impressive growth rate and a monthly production of up to about 550g of mushroom. A shorter time for mycelium growth on one whole baglog (21days) and the highest yield of Oyster mushroom (550g) were obtained from cultivation medium added with 20g of biochar. Our results demonstrate that the biochar-based bio-fertilizer produced from microwave vacuum pyrolysis of PKS shows exceptional promise as growth promoting material for mushroom cultivation.
  12. Fulltext Susceptibility and tolerance of rice crop to salt threat: Physiological and metabolic inspections
    Ma NL, Che Lah WA, Abd Kadir N, Mustaqim M, Rahmat Z, Ahmad A, et al.
    PLoS One, 2018;13(2):e0192732.
    PMID: 29489838 DOI: 10.1371/journal.pone.0192732
    Salinity threat is estimated to reduce global rice production by 50%. Comprehensive analysis of the physiological and metabolite changes in rice plants from salinity stress (i.e. tolerant versus susceptible plants) is important to combat higher salinity conditions. In this study, we screened a total of 92 genotypes and selected the most salinity tolerant line (SS1-14) and most susceptible line (SS2-18) to conduct comparative physiological and metabolome inspections. We demonstrated that the tolerant line managed to maintain their water and chlorophyll content with lower incidence of sodium ion accumulation. We also examined the antioxidant activities of these lines: production of ascorbate peroxidase (APX) and catalase (CAT) were significantly higher in the sensitive line while superoxide dismutase (SOD) was higher in the tolerant line. Partial least squares discriminant analysis (PLS-DA) score plots show significantly different response for both lines after the exposure to salinity stress. In the tolerant line, there was an upregulation of non-polar metabolites and production of sucrose, GABA and acetic acid, suggesting an important role in salinity adaptation. In contrast, glutamine and putrescine were noticeably high in the susceptible rice. Coordination of different strategies in tolerant and susceptible lines show that they responded differently after exposure to salt stress. These findings can assist crop development in terms of developing tolerance mechanisms for rice crops.
  13. Fulltext Biowastes of slaughterhouses and wet markets: an overview of waste management for disease prevention
    Al-Gheethi A, Ma NL, Rupani PF, Sultana N, Yaakob MA, Mohamed RMSR, et al.
    Environ Sci Pollut Res Int, 2023 Jun;30(28):71780-71793.
    PMID: 34585345 DOI: 10.1007/s11356-021-16629-w
    Slaughterhouse and wet market wastes are pollutants that have been always neglected by society. According to the Food and Agriculture Organization of the United Nations, more than three billion and nineteen million livestock were consumed worldwide in 2018, which reflects the vast amount and the broad spectrum of the biowastes generated. Slaughterhouse biowastes are a significant volume of biohazards that poses a high risk of contamination to the environment, an outbreak of diseases, and insecure food safety. This work comprehensively reviewed existing biowaste disposal practices and revealed the limitations of technological advancements to eradicate the threat of possible harmful infectious agents from these wastes. Policies, including strict supervision and uniform minimum hygienic regulations at all raw food processing factories, should therefore be tightened to ensure the protection of the food supply. The vast quantity of biowastes also offers a zero-waste potential for a circular economy, but the incorporation of biowaste recycling, including composting, anaerobic digestion, and thermal treatment, nevertheless remains challenging.
  14. Fulltext Psychobiotic Effects of Multi-Strain Probiotics Originated from Thai Fermented Foods in a Rat Model
    Luang-In V, Katisart T, Konsue A, Nudmamud-Thanoi S, Narbad A, Saengha W, et al.
    Food Sci Anim Resour, 2020 Nov;40(6):1014-1032.
    PMID: 33305285 DOI: 10.5851/kosfa.2020.e72
    This work aimed to investigate the psychobiotic effects of six bacterial strains on the mind and behavior of male Wistar rats. The probiotic (PRO) group (n=7) were rats pre-treated with antibiotics for 7 days followed by 14-day probiotic administration, antibiotics (ANT) group (n=7) were rats treated with antibiotics for 21 days without probiotics. The control (CON) group (n=7) were rats that received sham treatment for 21 days. The six bacterial strains with probiotic properties were mostly isolated from Thai fermented foods; Pedicoccus pentosaceus WS11, Lactobacillus plantarum SK321, L. fermentum SK324, L. brevis TRBC 3003, Bifidobacterium adolescentis TBRC 7154 and Lactococcus lactis subsp. lactis TBRC 375. The probiotics were freeze-dried into powder (6×109 CFU/5 g) and administered to the PRO group via oral gavage. Behavioral tests were performed. The PRO group displayed significantly reduced anxiety level and increased locomotor function using a marble burying test and open field test, respectively and significantly improved short-term memory performance using a novel object recognition test. Antibiotics significantly reduced microbial counts in rat feces in the ANT group by 100 fold compared to the PRO group. Probiotics significantly enhanced antioxidant enzymatic and non-enzymatic defenses in rat brains as assessed using catalase activity and ferric reducing antioxidant power assay, respectively. Probiotics also showed neuroprotective effects with less pyknotic cells and lower frequency of vacuolization in cerebral cortex. This multi-strain probiotic formulation from Thai fermented foods may offer a potential to develop psychobiotic-rich functional foods to modulate human mind and behaviors.
  15. Enhanced humification via lignocellulosic pretreatment in remediation of agricultural solid waste
    Ma J, Ma NL, Fei S, Liu G, Wang Y, Su Y, et al.
    Environ Pollut, 2024 Apr 01;346:123646.
    PMID: 38402938 DOI: 10.1016/j.envpol.2024.123646
    Stover and manure are the main solid waste in agricultural industry. The generation of stover and manure could lead to serious environmental pollution if not handled properly. Composting is the potential greener solution to remediate and reduce agricultural solid waste, through which stover and manure could be remediated and converted into organic fertilizer, but the long composting period and low efficiency of humic substance production are the key constraints in such remediation approach. In this study, we explore the effect of lignocellulose selective removal on composting by performing chemical pretreatment on agricultural waste followed by utilization of biochar to assist in the remediation by co-composting treatment and reveal the impacts of different lignocellulose component on organic fertilizer production. Aiming to discover the key factors that influence humification during composting process and improve the composting quality as well as comprehensive utilization of agricultural solid waste. The results demonstrated that the removal of selective lignin or hemicellulose led to the shift of abundances lignocellulose-degrading bacteria, which in turn accelerated the degradation of lignocellulose by almost 51.2%. The process also facilitated the remediation of organic waste via humification and increased the humic acid level and HA/FA ratio in just 22 days. The richness of media relies on their lignocellulose content, which is negatively correlated with total nitrogen content, humic acid (HA) content, germination index (GI), and pH, but positively correlated with fulvic acid (FA) and total organic carbon (TOC). The work provides a potential cost effective and efficient framework for agricultural solid waste remediation and reduction.
  16. Upcycling crab shell waste into biochar for treatment of palm oil mill effluent via microwave pyrolysis and activation
    Yang Y, Foong SY, He Y, Liew RK, Ma NL, Yek PNY, et al.
    Environ Res, 2024 May 01;248:118282.
    PMID: 38295974 DOI: 10.1016/j.envres.2024.118282
    The escalating consumer demand for crabs results in a growing amount of waste, including shells, claws, and other non-edible parts. The resulting crab shell waste (CSW) is disposed of via incineration or landfills which causes environmental pollution. CSW represents a potential biological resource that can be transformed into valuable resources via pyrolysis technique. In this study, microwave pyrolysis of CSW using self-purging, vacuum, and steam activation techniques was examined to determine the biochar production yield and its performance in treating palm oil mill effluent (POME). The biochar produced through microwave pyrolysis exhibits yields ranging from 50 to 61 wt%, showing a hard texture, low volatile matter content (≤34.1 wt%), and high fixed carbon content (≥58.3 wt%). The KOH-activated biochar demonstrated a surface area of up to 177 m2/g that is predominantly composed of mesopores, providing a good amount of adsorption sites for use as adsorbent. The biochar activated with steam removed 8.3 mg/g of BOD and 42 mg/g of COD from POME. The results demonstrate that microwave pyrolysis of CSW is a promising technology to produce high-quality biochar as an adsorbent for POME treatment.
  17. Gymnemic acid alleviates gut barrier disruption and lipid dysmetabolism via regulating gut microbiota in HFD hamsters
    Li Y, Sun M, Tian X, Bao T, Yu Q, Ma NL, et al.
    J Nutr Biochem, 2024 Nov;133:109709.
    PMID: 39053860 DOI: 10.1016/j.jnutbio.2024.109709
    Gut microbiota dysbiosis and gut barrier disruption are key events associated with high-fat diet (HFD)-induced systemic metabolic disorders. Gymnemic acid (GA) has been reported to have an important role in alleviating HFD-induced disorders of glycolipid metabolism, but its regulatory role in HFD-induced disorders of the gut microbiota and gut barrier function has not been elucidated. Here we showed that GA intervention in HFD-induced hamsters increased the relative abundance of short-chain fatty acid (SCFA)-producing microbes including Lactobacillus (P
  18. Fulltext Application of antimicrobial, potential hazard and mitigation plans
    Khoo SC, Goh MS, Alias A, Luang-In V, Chin KW, Ling Michelle TH, et al.
    Environ Res, 2022 Dec;215(Pt 1):114218.
    PMID: 36049514 DOI: 10.1016/j.envres.2022.114218
    The tremendous rise in the consumption of antimicrobial products had aroused global concerns, especially in the midst of pandemic COVID-19. Antimicrobial resistance has been accelerated by widespread usage of antimicrobial products in response to the COVID-19 pandemic. Furthermore, the widespread use of antimicrobial products releases biohazardous substances into the environment, endangering the ecology and ecosystem. Therefore, several strategies or measurements are needed to tackle this problem. In this review, types of antimicrobial available, emerging nanotechnology in antimicrobial production and their advanced application have been discussed. The problem of antimicrobial resistance (AMR) due to antibiotic-resistant bacteria (ARB)and antimicrobial resistance genes (AMG) had become the biggest threat to public health. To deal with this problem, an in-depth discussion of the challenges faced in antimicrobial mitigations and potential alternatives was reviewed.
  19. Processed Bamboo as a Novel Formaldehyde-Free High-Performance Furniture Biocomposite
    Ge S, Ma NL, Jiang S, Ok YS, Lam SS, Li C, et al.
    ACS Appl Mater Interfaces, 2020 Jul 08;12(27):30824-30832.
    PMID: 32544314 DOI: 10.1021/acsami.0c07448
    We used an innovative approach involving hot pressing, low energy consumption, and no adhesive to transform bamboo biomass into a natural sustainable fiber-based biocomposite for structural and furniture applications. Analyses showed strong internal bonding through mechanical "nail-like" nano substances, hydrogen, and ester and ether bonds. The biocomposite encompasses a 10-fold increase in internal bonding strength with improved water resistance, fire safety, and environmentally friendly properties as compared to existing furniture materials using hazardous formaldehyde-based adhesives. As compared to natural bamboo material, this new biocomposite has improved fire and water resistance, while there is no need for toxic adhesives (mostly made from formaldehyde-based resin), which eases the concern of harmful formaldehyde-based VOC emission and ensures better indoor air quality. This surpasses existing structural and furniture materials made by synthetic adhesives. Interestingly, our approach can 100% convert discarded bamboo biomass into this biocomposite, which represents a potentially cost reduction alternative with high revenue. The underlying fragment riveting and cell collapse binding are obviously a new technology approach that offers an economically and sustainable high-performance biocomposite that provides solutions to structural and furniture materials bound with synthetic adhesives.
  20. Environmental management of two of the world's most endangered marine and terrestrial predators: Vaquita and cheetah
    Lam SS, Chew KW, Show PL, Ma NL, Ok YS, Peng W, et al.
    Environ Res, 2020 11;190:109966.
    PMID: 32829186 DOI: 10.1016/j.envres.2020.109966
    Two of the world most endangered marine and terrestrial species are at the brink of extinction. The vaquita (Phocoena sinus) is the smallest existing cetacean and the population has declined to barely 22 individuals now remaining in Mexico's Gulf of California. With the ongoing decline, it is likely to go extinct within few years. The primary threat to this species has been mortality as a result of by-catch from gillnet fishing as well as environmental toxic chemicals and disturbance. This has called for the need to establish a National Park within the Gulf of California to expand essential habitat and provide the critical ecosystem protection for vaquita to thrive and multiply, given that proper conservation enforcement and management of the park are accomplished. In the terrestrial environment, the cheetah (Acinonyx jubatus) is reduced to a low number worldwide with the Iran subpopulation currently listed as Critically Endangered and the Indian subpopulation already extinct. There is a need for conservation efforts due to habitat loss, but also an indication of the conspicuous threat of illegal trade and trafficking from Africa and Arab countries in the Middle East. Funds have also been set up to provide refuges for the cheetah by working directly with farmers and landowners, which is a critical movement in adaptive management. These are the potential options for the preservation and possibly the expansion of the overall vaquita and cheetah populations.
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