Displaying all 6 publications

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  1. Ham AS, Gomez Hjerthen I, Sudhir A, Pandit L, Reddy YM, Murthy JM, et al.
    Mult Scler, 2024 Nov;30(13):1674-1682.
    PMID: 39392718 DOI: 10.1177/13524585241286671
    OBJECTIVES: The objectives were to understand the employment impacts of myelin oligodendrocyte glycoprotein-associated antibody disease (MOGAD) on adults in an international cohort by determining lost employment, work hours, and wages.

    BACKGROUND: Clinically, MOGAD can be associated with significant disability; however, its socioeconomic consequences for adults are barely reported.

    METHODS: Participants of potential working age (18-70 years old) with neurologist-diagnosed MOGAD were recruited from clinical sites in 13 countries, April 2022 to August 2023. Each participant completed a one-time survey. Regression models assessed associations with post-MOGAD (1) unemployment and (2) work hours.

    RESULTS: A total of 117 participants (66.7% female), mean age 39.7 years, median disease duration 3 years (25th, 75th percentile: 1, 7) were analyzed. Employment post-MOGAD reduced from 74 (63.2%) to 57 (48.7%) participants. Participants employed pre-diagnosis reduced their work hours, on average, from 31.6 hours/week to 19.5 hours/week post-diagnosis. Residence in a high-income country was statistically significantly associated with post-diagnosis employment and higher weekly work hours. Depressed mood was associated with unemployment. MOGAD-related pain and history of myelitis were independently associated with lost work hours.

    CONCLUSION: MOGAD can have significant impacts on adult employment, particularly in non-high-income countries. Depressed mood and pain are potentially modifiable factors related to socioeconomic status in MOGAD.

    Matched MeSH terms: Unemployment/statistics & numerical data
  2. Ismail AH, Baw R, Sidi H, Guan NC, Midin M, Nik Jaafar NR, et al.
    Compr Psychiatry, 2014 Jan;55 Suppl 1:S29-33.
    PMID: 23623640 DOI: 10.1016/j.comppsych.2013.03.009
    The present study aimed to determine the prevalence and associated factors of orgasmic dysfunction among Malay women with type 2 diabetes mellitus in Malaysia.
    Matched MeSH terms: Unemployment/statistics & numerical data
  3. Lubis R, Bulgiba A, Kamarulzaman A, Hairi NN, Dahlui M, Peramalah D
    Prev Med, 2013;57 Suppl:S54-6.
    PMID: 23352555 DOI: 10.1016/j.ypmed.2013.01.006
    To determine the predictors of death in Malaysian HIV-infected patients undergoing antiretroviral therapy (ART).
    Matched MeSH terms: Unemployment/statistics & numerical data
  4. Lee SP, Sagayadevan V, Vaingankar JA, Chong SA, Subramaniam M
    J Anxiety Disord, 2015 May;32:73-80.
    PMID: 25863827 DOI: 10.1016/j.janxdis.2015.03.008
    Previous nationally representative studies have reported prevalence of DSM-IV generalized anxiety disorder (GAD). However, subthreshold and threshold GAD expressions remain poorly understood. The current study examined the prevalence, correlates and co-morbidity of a broader diagnosis of GAD in Singapore. The Singapore Mental Health Study (SMHS) was an epidemiological survey conducted in the population (N=6616) aged 18 years and older. The Composite International Diagnostic Interview version 3.0 (CIDI 3.0) was used to establish mental disorder diagnoses. The lifetime prevalence for subthreshold GAD (2.1%) and threshold GAD (1.5%) in the current sample was found to be lower than in Western populations. Younger age group, Indian ethnicity, previously married, chronic physical conditions, and being unemployed were associated with higher odds of having more severe expression of generalized anxiety. The relatively lower prevalence rate of subthreshold GAD expression suggests possible cultural interferences in the reporting and manifestation of anxiety symptomatology. Despite the low prevalence, significant impacts on functioning and comorbidity among subthreshold generalized anxiety cases indicate the importance of early treatment to ensure a better prognosis.
    Matched MeSH terms: Unemployment/statistics & numerical data
  5. Ramakrishnan K, Loh SY, Omar Z
    Spinal Cord, 2011 Sep;49(9):986-9.
    PMID: 21556013 DOI: 10.1038/sc.2011.47
    Secondary analysis of cross-sectional data.
    Matched MeSH terms: Unemployment/statistics & numerical data
  6. Chua YC, Abdin E, Tang C, Subramaniam M, Verma S
    Schizophr Res, 2019 09;211:63-68.
    PMID: 31327504 DOI: 10.1016/j.schres.2019.07.009
    Most studies on predictors of vocational outcomes are cross-sectional and results are varied. This study aimed to examine the vocational rates of patients with first-episode psychosis (FEP), identify factors predicting a lack of engagement in age-appropriate roles, and evaluate the predictive ability of a model with baseline sociodemographic information and 2-year symptom and functioning trajectories on vocational outcomes. The Singapore Early Psychosis Intervention Program (EPIP) has maintained a standing database on patient clinico-demographic information. The primary outcome, vocational status, was operationalized as "meaningfully employed", that is, being gainfully employed or engaged in an age-appropriate role, and "unemployed". Using logistic regression, the predictive ability of the proposed model was evaluated. Vocational data was available for 1177 patients accepted into EPIP between 2001 and 2012. At the end of two years in the service, 829 (70.4%) patients were meaningfully employed and 348 (29.6%) patients were unemployed. The binary logistic regression model on the prediction of 2-year vocational outcomes yielded an AUC of 0.759 (SE = 0.016, p-value 
    Matched MeSH terms: Unemployment/statistics & numerical data*
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