Displaying all 9 publications

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  1. Motharasan Manogaran, Nur Adeela Yasid, Siti Aqlima Ahmad
    MyJurnal
    Glyphosate is an agricultural herbicide with usage in the amounts of thousands of tonnes per year
    in Malaysia. In certain soils, glyphosate can persist for months and its removal through
    bioremediation is the most economical and practical. A previously isolated glyphosate-degrading
    bacterium showed substrate inhibition to the degradation rate. Important degradation inhibition
    constants can be reliably obtained through nonlinear regression modelling of the degradation rate
    profile using substrate inhibition models such as Luong, Yano, Teissier-Edward, Aiba, Haldane,
    Monod and Han and Levenspiel models. The Aiba model was chosen as the best model based on
    statistical tests such as root-mean-square error (RMSE), adjusted coefficient of determination
    (adjR2), bias factor (BF) and accuracy factor (AF). The calculated values for the Aiba-Edwards
    constants qmax (the maximum specific substrate degradation rate (h−1), Ks (concentration of
    substrate at the half maximal degradation rate (mg/L) and Ki (inhibition constant (mg/L)) were
    131±34, 4446±2073, and 24323±5094, respectively. Novel constants obtained from the
    modelling exercise would be useful for further secondary modelling implicating the effect of
    media conditions and other factors on the degradation of glyphosate by this bacterium.
  2. Abubakar Aisami, Allamin Ibrahim Alkali, Nur Adeela Yasid
    MyJurnal
    Phenolic compounds or phenols are a group of aromatic compounds that comprises a hydroxyl
    group (OH) that is directly bonded to an aromatic ring. Phenols are injurious to organisms even
    at even low concentrations with many of them are categorized as dangerous pollutants because of
    their likely harm to human well-being. This review attempts to discuss the various merits and
    demerits of immobilization matrices employed for phenol-degrading microorganisms’
    immobilization. One of several key points of cellular immobilization is the capacity to protect
    bioremediation agents towards toxic levels of specific toxicants and safeguarding from predatory
    microorganisms. However, this shielding course of action should never impede the diffusion of
    substrates into the pores of the immobilization structure. In the end the choice of a particular
    immobilization method will strongly hinge on aspects of economy, safety and efficacy.
  3. Motharasan Manogaran, Mohd Yunus Shukor, Nur Adeela Yasid, Wan Lutfi Wan Johari, Siti Aqlima Ahmad
    MyJurnal
    Commercialisation of glyphosate [N-(phosphonomethyl)glycine] in the early 1970s has left a big leap in the agriculture sector. This is due to its effectiveness in controlling a wide range of weeds. Glyphosate translocates well in plants. In addition, with added surfactant in its formulae, it can also be used in wet conditions. Its ability to kill weeds by targeting the 5-enolpyruvyl-shikimate-3-phosphate synthase (EPSPS) makes no competing herbicide analogs in its class. Considering its cost effectiveness, only small amount is needed to cover a large sector in agricultural land. The most important aspect in the success of glyphosate is the introduction of transgenic, glyphosate-resistant crops in 1996. However, glyphosate is not an environmental friendly herbicide. This systematic herbicide has raised environmental concern due to its excessive use in agriculture. Studies have shown traces of glyphosate found in drinking water. Meanwhile, it's rapid binding on soil particles possesses adverse effect to soil organisms. Glyphosate degradation in soil usually carried out by microbial activity. Microbes’ capable utilising glyphosate mainly as phosphate source. However, the activity of C-P lyase in breaking down glyphosate have not clearly understood. This review presents a collective summary on the understanding on how glyphosate works and its environmental fate.
  4. Syahir Habib, Siti Aqlima Ahmad, Mohd Yunus Abd Shukor, Nur Adeela Yasid, Wan Lutfi Wan Johari
    MyJurnal
    The increase of anthropogenic activities and growth of technology in Antarctica is fuelled by the high demand for petroleum hydrocarbons needed for daily activities. Oil and fuel spills that occur during explorations have caused hydrocarbon pollution in this region, prompting concern for the environment by polar communities and the larger world community. Crude oil and petroleum hydrocarbon products contain a wide variety of lethal components with high toxicity and low biodegradability. Hydrocarbon persistence in the Antarctic environment only worsens the issues stemming from environmental pollution as they can be long-term. Numerous efforts to lower the contamination level caused by these pollutants have been conducted mainly in bioremediation, an economical and degrading-wise method. Bioremediation mainly functions on conversion of complex toxic compounds to simpler organic compounds due to the consumption of hydrocarbons by microorganisms as their energy source. This review presents a summary of the collective understanding on bioremediation of petroleum hydrocarbons by microorganisms indigenous to the Antarctic region from past decades to current knowledge.
  5. Syahir Habib, Mohd Yunus Abd Shukor, Nur Adeela Yasid, Wan Lutfi Wan Johari
    MyJurnal
    Petroleum hydrocarbons remain as the major contaminants that could be found across the world.
    Remediation approach through the utilisation of microbes as the bioremediation means widely
    recognised due to their outstanding values. As a result, scientific reports on the isolation and
    identification of new hydrocarbon-degrading strains were on the rise. Colourimetric-based assays
    are one of the fastest methods to identify the capability of hydrocarbon-degrading strains in both
    qualitative and quantitative assessment. In this study, the hydrocarbon-degrading potential of
    nine bacterial isolates was observed via 2,6-dichlorophenolindophenol (DCPIP) test. Two potent
    diesel-utilising isolates show a distinctive tendency to utilise aromatic (ADL15) and aliphatic
    (ADL36) hydrocarbons. Both isolates prove to be a good candidate for bioremediation of wide
    range of petroleum hydrocarbon components.
  6. Abubakar Aisami, Nur Adeela Yasid, Wan Lutfi Wan Johari, Mohd Yunus Shukor
    MyJurnal
    The Q10 value is tied to an increase in the surrounding temperature with an increase in 10 ◦C,
    and usually resulted in a doubling of the reaction rate. When this happens, the Q10 value for the
    reaction is 2. This value holds true to numerous biological reactions. To date, the Q10 value for
    the biodegradation of phenol is almost not reported. The Q10 values can be determined from the
    Arrhenius plots. In this study, the growth rate or biodegradation rates in logarithmic value for
    the bacterium Pseudomonas sp. AQ5-04 was plotted against 1000/temperature (Kelvin) and the
    slope of the Arrhenius curve is the value of the Ea, which was utilized to obtain the Q10. The
    value obtained in this work was 1.834, which is slightly lower than the normal range of between
    2 and 3 for the biodegradation rates of hydrocarbon in general and shows that this bacterium is a
    very efficient phenol-degrading bacterium.
  7. Ain Aqilah Basirun, Mohd Khalizan Sabullah, Mohd Yunus Abd Shukor, Nur Adeela Yasid, Nor Aripin Shamaan, Siti Aqlima Ahmad
    MyJurnal
    Recently, the contamination of heavy metals towards the environment especially in aquatic system has drastically increased. Heavy metals are able to transform into persistent metallic compound in which it can be accumulated within the organisms’ body system, disrupting the food chain and eventually threatened the human life. The occurrence of heavy metals spillage in the rivers and lakes are due to the careless disposal of excess heavy metals used for human activities. The accumulation of heavy metals in water system will affect all aquatic organisms especially fish. The toxicity of copper in fish can be determined by several changes in the fish under treatment with heavy metals sub-lethal concentration, LC50 within 96-hours period of acute exposure. Therefore, fish can be considered as a high potential biomarker for monitoring heavy metals pollution in aquatic system. Several selective organs are highly sensitive to the xenobiotic pollution and express changes to the exposure. One of the most potential biomarker is the biochemical biomarker of cholinesterase (ChE) inhibition by heavy metals in fish has been well studied in pollution monitoring recently. Thus, this paper gives an overview of the manipulation of fish as a biomarker of heavy metals through enzymatic reaction which have proven to be very useful in the environmental pollution monitoring.
  8. Chee, H.S., Motharasan Manogaran, Yakasai, M.H., Rahman, M.F.A., Nur Adeela Yasid, Zarizal Suhaili, et al.
    MyJurnal
    The issue of heavy metal contamination and toxic xenobiotics has become a rapid global
    concern. This has ensured that the bioremediation of these toxicants, which are being carried out
    using novel microbes. A bacterium with the ability to reduce molybdenum has been isolated
    from contaminated soils and identified as Serratia marcescens strain DR.Y10. The bacterium
    reduced molybdenum (sodium molybdate) to molybdenum blue (Mo-blue) optimally at pHs of
    between 6.0 and 6.5 and temperatures between 30°C and 37°C. Glucose was the best electron
    donor for supporting molybdate reduction followed by sucrose, adonitol, mannose, maltose,
    mannitol glycerol, salicin, myo-inositol, sorbitol and trehalose in descending order. Other
    requirements include a phosphate concentration of 5 mM and a molybdate concentration of
    between 10 and 30 mM. The absorption spectrum of the Mo-blue produced was similar to the
    previously isolated Mo-reducing bacterium and closely resembles a reduced phosphomolybdate.
    Molybdenum reduction was inhibited by Hg (ii), Ag (i), Cu (ii), and Cr (vi) at 78.9, 69.2, 59.5
    and 40.1%, respectively. We also screen for the ability of the bacterium to use various organic
    xenobiotics such as phenol, acrylamide, nicotinamide, acetamide, iodoacetamide, propionamide,
    acetamide, sodium dodecyl sulfate (SDS) and diesel as electron donor sources for aiding
    reduction. The bacterium was also able to grow using amides such as acrylamide, propionamide
    and acetamide without molybdenum reduction. The unique ability of the bacterium to detoxify
    many toxicants is much in demand, making this bacterium a vital means of bioremediation.
  9. Abubakar M. Umar, Tham, Lik Gin, Natarajan Perumal, Nur Adeela Yasid, Hassan Mohd Daud, Mohd Yunus Shukor
    MyJurnal
    Acetylcholinesterase (AChE) is usually used as an inhibitive assay for insecticides. A lesserknown
    property of AChE is its inhibition by heavy metals. In this work, we evaluate an AChE
    from brains of Clarias batrachus (catfish) exposed to wastes from aquaculture industry as an
    inhibitive assay for heavy metals. We discovered that the AChE was inhibited completely by
    Hg2+, Ag2+, Pb2+, Cu2+, Cd2+, Cr6+ and Zn2+ during initial screening. When tested at various
    concentrations, the heavy metals exhibited exponential decay type inhibition curves. The
    calculated IC50 (mg/L) for the heavy metals Ag2+, Cu2+, Hg2+, Cr6+ and Cd2+ were 0.088, 0.078,
    0.071, 0.87 and 0.913, respectively. The IC50 for these heavy metals are comparable, and some
    are lower than the IC50 values from the cholinesterases from previously studied fish. The assay
    can be carried out in less than 30 minutes at ambient temperature.
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