Phenolic compounds or phenols are a group of aromatic compounds that comprises a hydroxyl
group (OH) that is directly bonded to an aromatic ring. Phenols are injurious to organisms even
at even low concentrations with many of them are categorized as dangerous pollutants because of
their likely harm to human well-being. This review attempts to discuss the various merits and
demerits of immobilization matrices employed for phenol-degrading microorganisms’
immobilization. One of several key points of cellular immobilization is the capacity to protect
bioremediation agents towards toxic levels of specific toxicants and safeguarding from predatory
microorganisms. However, this shielding course of action should never impede the diffusion of
substrates into the pores of the immobilization structure. In the end the choice of a particular
immobilization method will strongly hinge on aspects of economy, safety and efficacy.