Affiliations 

  • 1 Department of Psychiatry, Clinic for Neurology and Psychiatry for Children and Youth, Belgrade, Serbia
  • 2 Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children's Hospital, Rome, Italy
  • 3 A.J. Drexel Autism Institute, Drexel University, Philadelphia, Pennsylvania, USA
  • 4 University of the West Indies, Kingston, Jamaica
  • 5 Child and Adolescent Psychiatry Unit, Dr Behcet Uz Children's Research and Training Hospital, Izmir, Turkey
  • 6 Child Psychiatry Unit, Bursa Dortcelik Children's Hospital, Bursa, Turkey
  • 7 Department of Psychiatry, Centre of Excellence in Mental health, Atal Bihari Vajpayee Institute of Medical Sciences; Dr. Ram Manohar Lohia Hospital, New Delhi, India
  • 8 INCLEN Trust, New Delhi, India
  • 9 Research Division, Hospital Psiquiátrico Infantil "Dr. Juan N. Navarro," Secretaría de Salud, Mexico City, Mexico
  • 10 Hospital Sant Joan de Déu, Barcelona, Spain
  • 11 Hospital de Villarrica, Department of Mental Health, Universidad de La Frontera, Temuco, Chile
  • 12 Mental Health Center, Tbilisi, Georgia
  • 13 Ilia State University, Tbilisi, Georgia
  • 14 Pontifícia Universidade Católica de São Paulo, São Paulo, Brazil
  • 15 National Institute for Maternal and Child Health, Bucharest, Romania
  • 16 Institute of Nursing and Health Research, University of Ulster, Coleraine, UK
  • 17 Clinical Research Centre & Department of Pediatrics, Sibu Hospital, Ministry of Health Malaysia, Sibu, Malaysia
  • 18 Environmental Health Investigations Branch, California Department of Public Health, Richmond, California, USA
  • 19 University of Connecticut, Storrs, Connecticut, USA
  • 20 Developmental Department, University Children's Hospital, Skopje, Macedonia
  • 21 Language and Cognition Laboratory, Hospital General Dr. Manuel Gea González, Mexico City, Mexico
  • 22 Faculty of Social Science, Education and Child Studies, Clinical Neuroscience and Developmental Disorders, Leiden University, Leiden, The Netherlands
  • 23 Faculty of Nursing, Mu'tah University, Mu'tah, Jordan
  • 24 World Health Organization, Geneva, Switzerland
  • 25 Department of Women's and Children's Health, Skaraborgs Hospital, Skövde, Sweden
Autism Res, 2021 12;14(12):2544-2554.
PMID: 34346193 DOI: 10.1002/aur.2586

Abstract

The Childhood Autism Rating Scale (CARS) is a simple and inexpensive tool for Autism spectrum disorder (ASD) assessments, with evidenced psychometric data from different countries. However, it is still unclear whether ASD symptoms are measured the same way across different societies and world regions with this tool, since data on its cross-cultural validity are lacking. This study evaluated the cross-cultural measurement invariance of the CARS among children with ASD from six countries, for whom data were aggregated from previous studies in India (n = 101), Jamaica (n = 139), Mexico (n = 72), Spain (n = 99), Turkey (n = 150), and the United States of America (n = 186). We analyzed the approximate measurement invariance based on Bayesian structural equation modeling. The model did not fit the data and its measurement invariance did not hold, with all items found non-invariant across the countries. Items related to social communication and interaction (i.e., relating to people, imitation, emotional response, and verbal and nonverbal communication) displayed lower levels of cross-country non-invariance compared to items about stereotyped behaviors/sensory sensitivity (i.e., body and object use, adaptation to change, or taste, smell, and touch response). This study found that the CARS may not provide cross-culturally valid ASD assessments. Thus, cross-cultural comparisons with the CARS should consider first which items operate differently across samples of interest, since its cross-cultural measurement non-invariance could be a source of cross-cultural variability in ASD presentations. Additional studies are needed before drawing valid recommendations in relation to the cultural sensitivity of particular items.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.