Affiliations 

  • 1 Department of Biomedical Imaging, University of Malaya Research Imaging Centre, Kuala Lumpur, Malaysia
  • 2 Department of Radiology, Hospital Sultan Ismail, Johor, Malaysia
  • 3 Department of Surgery, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 4 Department of Surgery, Subang Jaya Medical Centre, Kuala Lumpur, Malaysia
Curr Med Imaging, 2021;17(4):552-558.
PMID: 33030134 DOI: 10.2174/1573405616666201007161119

Abstract

BACKGROUND: Primary breast angiosarcoma is a rare malignancy with non-specific clinical and radiological findings.

CASE REPORT: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subsequently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of angiosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy.

DISCUSSION: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement.

CONCLUSION: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.