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In vitro antioxidant activity of Ficus carica L. latex from 18 different cultivars

Shahinuzzaman M 1 , Yaakob Z 2 , Anuar FH 3 , Akhtar P 2 , Kadir NHA 4 , Hasan AKM 5 Show all authors , Sobayel K 5 , Nour M 6 , Sindi H 6 , Amin N 7 , Sopian K 5 , Akhtaruzzaman M 8

Affiliations 

  • 1 Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor, Malaysia. [email protected]
  • 2 Department of Chemical and Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaaan Malaysia, UKM, 43600, Bangi, Selangor, Malaysia
  • 3 Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor, Malaysia
  • 4 School of Fundamental Science, Universiti Malaysia Terengganu, Terengganu, Malaysia
  • 5 Solar Energy Research Institute, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor, Malaysia
  • 6 Department of Electrical and Computer Engineering, Faculty of Engineering, King Abdulaziz University, 21589, Jeddah, Saudi Arabia
  • 7 Institute of Sustainable Energy, Universiti Tenaga Nasional (@The National Energy University), Jalan IKRAM-UNITEN, 43000, Kajang, Selangor, Malaysia
  • 8 Solar Energy Research Institute, Universiti Kebangsaan Malaysia, 43600, Bangi, Selangor, Malaysia. [email protected]
Sci Rep, 2020 07 02;10(1):10852.
PMID: 32616768 DOI: 10.1038/s41598-020-67765-1

Abstract

As synthetic antioxidants that are widely used in foods are known to cause detrimental health effects, studies on natural additives as potential antioxidants are becoming increasingly important. In this work, the total phenolic content (TPC) and antioxidant activity of Ficus carica Linn latex from 18 cultivars were investigated. The TPC of latex was calculated using the Folin-Ciocalteu assay. 1,1-Diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and ferric ion reducing antioxidant power (FRAP) were used for antioxidant activity assessment. The bioactive compounds from F. carica latex were extracted via maceration and ultrasound-assisted extraction (UAE) with 75% ethanol as solvent. Under the same extraction conditions, the latex of cultivar 'White Genoa' showed the highest antioxidant activity of 65.91% ± 1.73% and 61.07% ± 1.65% in DPPH, 98.96% ± 1.06% and 83.04% ± 2.16% in ABTS, and 27.08 ± 0.34 and 24.94 ± 0.84 mg TE/g latex in FRAP assay via maceration and UAE, respectively. The TPC of 'White Genoa' was 315.26 ± 6.14 and 298.52 ± 9.20 µg GAE/mL via the two extraction methods, respectively. The overall results of this work showed that F. carica latex is a potential natural source of antioxidants. This finding is useful for further advancements in the fields of food supplements, food additives and drug synthesis in the future.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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