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Impact of non-surgical periodontal therapy on serum Resistin and periodontal pathogen in periodontitis patients with obesity

Md Tahir K 1 , Ab Malek AH 1 , Vaithilingam RD 1 , Saub R 2 , Safii SH 1 , Rahman MT 3 Show all authors , Abdul Razak F 4 , Alabsi AM 5 , Baharuddin NA 6

Affiliations 

  • 1 Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia
  • 2 Department of Community Oral Health & Clinical Prevention, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia
  • 3 Dean Office, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia
  • 4 Department of Oral & Craniofacial Sciences, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia
  • 5 Faculty of Dentistry, MAHSA University, Jalan SP2, Bandar Saujana Putra, 42610, Jenjarom Kuala Langat, Selangor, Malaysia
  • 6 Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, Lembah Pantai, 50603, Kuala Lumpur, Malaysia. [email protected]
BMC Oral Health, 2020 02 14;20(1):52.
PMID: 32059714 DOI: 10.1186/s12903-020-1039-3

Abstract

BACKGROUND: Non-surgical periodontal therapy (NSPT) known as gold standard treatment in managing periodontitis. The aim of this study was to investigate the response of NSPT in periodontitis subjects who were obese. Clinical parameters of periodontitis, changes in serum resistin and periodontal pathogens in subgingival plaque were compared before and after NSPT in periodontitis subjects who were obese and with normal weight.

METHODS: A total of 48 periodontitis subjects (obese, n = 18; normal weight, n = 30) were recruited (hereafter will be referred as participants) to participate into a prospective, before and after clinical trial. Obesity status is defined by body mass index (BMI) criteria (obese: ≥30 kg/ m2; normal weight 

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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