Design, characterization, and evaluation of intranasal delivery of ropinirole-loaded mucoadhesive nanoparticles for brain targeting

Jafarieh O 1 , Md S 1 , Ali M 1 , Baboota S 1 , Sahni JK 1 , Kumari B 1 Show all authors , Bhatnagar A 2 , Ali J 1

Affiliations 

  • 1 a Department of Pharmaceutics, Faculty of Pharmacy , Jamia Hamdard , Hamdard Nagar , New Delhi , India
  • 2 e Department of Radiopharmaceuticals , Institute of Nuclear Medicine and Allied Sciences (INMAS) , New Delhi , India
Drug Dev Ind Pharm, 2015;41(10):1674-81.
PMID: 25496439 DOI: 10.3109/03639045.2014.991400

Abstract

Parkinson disease (PD) is a common, progressive neurodegenerative disorder, characterized by marked depletion of striatal dopamine and degeneration of dopaminergic neurons in the substantia nigra.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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