Molybdenum disulfide nanosheet decorated with silver nanoparticles for selective detection of dopamine

Sookhakian M 1 , Basirun WJ 2 , Goh BT 3 , Woi PM 4 , Alias Y 5

Affiliations 

  • 1 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; Low Dimensional Materials Research Centre, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address: [email protected]
  • 2 University Malaya Centre for Ionic Liquids, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia; Institute of Nanotechnology and Catalysis Research (NanoCat), University Malaya, Kuala Lumpur 50603, Malaysia
  • 3 Low Dimensional Materials Research Centre, Department of Physics, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • 4 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; University Malaya Centre for Ionic Liquids, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia
  • 5 Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia; University Malaya Centre for Ionic Liquids, Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address: [email protected]
Colloids Surf B Biointerfaces, 2019 Apr 01;176:80-86.
PMID: 30594706 DOI: 10.1016/j.colsurfb.2018.12.058

Abstract

A metal-inorganic composite, comprises of silver-molybdenum disulfide nanosheets (Ag@MoS2) was synthesized at low temperature. The Ag@MoS2 composite was drop-casted onto a glassy carbon electrode (GCE) for a highly selective dopamine (DA) detection in the presence of interfering compounds such as uric acid (UA) and ascorbic acid (AA). The physicochemical analysis of the nanosheets was carried out with X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy. The as-prepared Ag@MoS2-modified GCE displayed excellent electrocatalytic activity toward DA oxidation, with a 0.2 μM detection limit at a signal-to-noise ratio of 3 and an extensive linear detection range from 1 μM to 500 μM (R2 = 0.9983). The fabricated non-enzymatic electrochemical sensor demonstrated superior selectivity and stability for the detection of DA with the removal of AA and UA interfering compounds.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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