Affiliations 

  • 1 Research Institute of Biotechnology & Medical Converged Science, Dongguk University-Seoul, Goyang-si, 10326, Republic of Korea
  • 2 Sao Paulo State University (UNESP), Institute of Science and Technology, Sorocaba, São Paulo, Zip Code 18087-180, Brazil
  • 3 Laboratorio de Investigación Interdisciplinaria, Área de Nanoestructuras y Biomateriales, Escuela Nacional de Estudios Superiores, Unidad Leon, Universidad Nacional Autonóma de México (UNAM), Boulevard UNAM No 2011. Predio El Saucillo y El Potrero, 37684, León, Guanajuato, Mexico
  • 4 Centro de Investigaciones en Óptica, A.P. 1-948, C.P. 37000, León, Guanajuato, Mexico
  • 5 Department of Physics and Chemistry, School of Engineering, São Paulo State University (UNESP), Ilha Solteira, SP, 15385-000, Brazil
  • 6 Department of Crop Science, Faculty of Agriculture, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia
  • 7 Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Allahabad, Uttar Pradesh, 211004, India
  • 8 Pharmacognosy Research Laboratories & Herbal Analysis Services UK, University of Greenwich, Medway Campus-Science, Grenville Building (G102/G107), Central Avenue, Chatham-Maritime, Kent, ME4 4TB, UK
  • 9 Department of Food Science and Biotechnology, Dongguk University, Ilsandong-gu, Goyang, Gyeonggi-do, 10326, Republic of Korea. [email protected]
J Nanobiotechnology, 2018 Sep 19;16(1):71.
PMID: 30231877 DOI: 10.1186/s12951-018-0392-8

Abstract

Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner. Nanotechnology offers multiple benefits in treating chronic human diseases by site-specific, and target-oriented delivery of precise medicines. Recently, there are a number of outstanding applications of the nanomedicine (chemotherapeutic agents, biological agents, immunotherapeutic agents etc.) in the treatment of various diseases. The current review, presents an updated summary of recent advances in the field of nanomedicines and nano based drug delivery systems through comprehensive scrutiny of the discovery and application of nanomaterials in improving both the efficacy of novel and old drugs (e.g., natural products) and selective diagnosis through disease marker molecules. The opportunities and challenges of nanomedicines in drug delivery from synthetic/natural sources to their clinical applications are also discussed. In addition, we have included information regarding the trends and perspectives in nanomedicine area.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.