Quality of life and recurrence of disease in patients with eosinophilic and non-eosinophilic 1 chronic rhinosinusitis with nasal polyposis

Khairuddin NK 1 , Salina H 2 , Gendeh BS 2 , Wan Hamizan AK 2 , Lund VJ 3

Affiliations 

  • 1 Universiti Kebangsaan Malaysia Medical Centre, Department of Otorhinolaryngology-Head and Neck Surgery, Kuala Lumpur, Malaysia. [email protected]
  • 2 Universiti Kebangsaan Malaysia Medical Centre, Department of Otorhinolaryngology-Head and Neck Surgery, Kuala Lumpur, Malaysia
  • 3 Royal National Throat Nose Ear Hospital, Professorial Unit, London, United Kingdom
Med J Malaysia, 2018 Feb;73(1):1-6.
PMID: 29531195

Abstract

OBJECTIVE: To assess the quality of life (QoL) and recurrence of disease in patients with eosinophilic (ECRSwNP) and non-eosinophilic chronic rhinosinusitis with nasal polyposis (non-ECRSwNP) post endoscopic sinus surgery (ESS).

METHODOLOGY: A cross-sectional comparative study was carried out in the Otorhinolaryngology - HNS Department, Universiti Kebangsaan Malaysia Medical Center (UKMMC). Subjective assessments of nasal symptoms and quality of life (QoL) using SNOT-22 and Visual Analogue Scale (VAS) and objective endoscopic assessment was undertaken using a modified Hadley endoscopic examination.

RESULTS: There was no significant statistical difference in the quality of life between the ECRSwNP and non-ECRSwNP groups as evidenced by the SNOT-22 score and the VAS comparison (p>0.05). However, there was a significant difference in terms of recurrence of disease with the presence of nasal polyps on endoscopic examination. (p = 0.016) CONCLUSION: In conclusion, we found that there is no significant difference in QoL between ECRSwNP and non- ECRSwNP. There is higher frequency of recurrence of nasal polyps amongst ECRSwNP.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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