Anti-staphylococcal properties of four plant extracts against sensitive and multi-resistant bacterial strains isolated from cattle and rabbits

Medina MFE 1 , Alaba PA 2 , Estrada-Zuñiga ME 1 , Velázquez-Ordoñez V 3 , Barbabosa-Pliego A 3 , Salem MZM 4 Show all authors , Alonso-Fresán MU 3 , Camacho-Díaz LM 5 , Salem AZM 6

Affiliations 

  • 1 Facultad de Ciencias, Universidad Autónoma del Estado de México, Toluca, Estado de México, Mexico
  • 2 Department of Chemical Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
  • 3 Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Estado de México, Mexico
  • 4 Forestry and Wood Technology Department, Faculty of Agriculture (EL-Shatby), Alexandria University, Alexandria, Egypt
  • 5 Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma de Guerrero, Km. 3.5 Carretera Cd. Altamirano-Iguala, CP 40660 Cd. Altamirano, Guerrero, Mexico. Electronic address: [email protected]
  • 6 Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Estado de México, Mexico. Electronic address: [email protected]
Microb Pathog, 2017 Dec;113:286-294.
PMID: 29101063 DOI: 10.1016/j.micpath.2017.10.053

Abstract

The aim of this study is to investigate the biopotency of methanolic extracts of Vitex mollis, Psidium guajava, Dalbergia retusa, and Crescential alata leaves against various staphylococcal strains isolated from cattle and rabbits. Methicillin-resistant S. aureus strains were isolated from cattle, while other strains were isolated from rabbits using standard methodology. The total phytochemical phenolic and saponins contents were obtained being the main groups of the antinutritional factors. The antimicrobial activity of the extracts against the standard culture of S. aureus (control) and S. aureus isolated from cattle and rabbits were investigated comparatively relative to that of oxacillin. It was found that both the control S. aureus and the isolated S. aureus are susceptible to all the four plant extracts, and sensitive to oxacillin. Of all the S. aureus including the control, MRSA2 is the most susceptible to all the extracts at 1000 μg/mL, except that of V. mollis where it is the least susceptible. Among all the plant extracts, P. guajava is the most active against MRSA2 and SOSA2. Therefore, the isolates from cattle (MRSA1 and MRSA2) are more susceptible to all the plant extracts than the isolates from rabbits. Among all the rabbit isolates, CoNS3 is the least susceptible to the extracts. Since all the plant extracts exhibit remarkable inhibitory activities against all the S. aureus strains, they are promising towards the production of therapeutic drugs.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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