Stridor in infants with subglottic cyst is rare. Mismanagement of such cases may
lead to respiratory compromise with a potentially serious and fatal outcome. The
diversity of the clinical presentations throws a great challenge in the diagnosis of
subglottic cysts. Manifestations vary as they depend on the size and location of
the cysts. We report the case of a 6-month-old girl who had a subglottic cyst
but managed as moderate croup till she developed worsening respiratory acidosis
which difficult intubation. Any case of premature infants with previous history of
neonatal intubation presenting with stridor should prompt clinicians to look for
possible cysts in the larynx. This is important because once the diagnosis is made, appropriate treatment may be given and unnecessary morbidity and mortality may
be avoided.