Affiliations 

  • 1 SGGS Institute of Engineering and Technology, Nanded, MS, India. Electronic address: [email protected]
  • 2 SGGS Institute of Engineering and Technology, Nanded, MS, India
  • 3 Eye Clinic, Susrusha Hospital, Nanded, MS, India
  • 4 Department of Electrical and Electronic Engineering, Center for Intelligent Signal and Imaging Research (CISIR), Universiti Teknologi Petronas, Tronoh, 32610 Seri Iskandar, Perak, Malaysia
Comput Biol Med, 2017 08 01;87:382-396.
PMID: 28595892 DOI: 10.1016/j.compbiomed.2017.04.016

Abstract

Accurate detection of diabetic retinopathy (DR) mainly depends on identification of retinal landmarks such as optic disc and fovea. Present methods suffer from challenges like less accuracy and high computational complexity. To address this issue, this paper presents a novel approach for fast and accurate localization of optic disc (OD) and fovea using one-dimensional scanned intensity profile analysis. The proposed method utilizes both time and frequency domain information effectively for localization of OD. The final OD center is located using signal peak-valley detection in time domain and discontinuity detection in frequency domain analysis. However, with the help of detected OD location, the fovea center is located using signal valley analysis. Experiments were conducted on MESSIDOR dataset, where OD was successfully located in 1197 out of 1200 images (99.75%) and fovea in 1196 out of 1200 images (99.66%) with an average computation time of 0.52s. The large scale evaluation has been carried out extensively on nine publicly available databases. The proposed method is highly efficient in terms of quickly and accurately localizing OD and fovea structure together compared with the other state-of-the-art methods.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.