Fulltext

A Rare Case of Alpha-Thalassaemia Intermedia in a Malay Patient Double Heterozygous for α+-Thalassaemia and a Mutation in α1 Globin Gene CD59 (GGCGAC)

George, E 1 , Tan, J.A.M.A. 2 , Nor Azian, A.S 3 , Rahimah, A. 4 , Zubaidah, Z. 3

Affiliations 

  • 1 Universiti Putra Malaysia
  • 2 Hospital Melaka
  • 3 Institute for Medical Research
  • 4 University of Malaya
Medical Journal of Malaysia, 2009;64(4):321-322.
MyJurnal

Abstract

A rare case of thalassaemia-intermedia involving a nondeletion alpha thalassemia point mutation in the α1-globin gene CD59 (GGCGAC) and a deletion α+ (-α3.7) thalassaemia in which use of high performance liquid chromatography (HPLC) C-gram Hb subtype profile and DNA molecular analysis helped establish the diagnosis.

MeSH terms
Similar publications