A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination

Britton S; Cheng Q; Sutherland CJ; McCarthy JS

doi:10.1186/s12936-015-0848-3

Fulltext

A simple, high-throughput, colourimetric, field applicable loop-mediated isothermal amplification (HtLAMP) assay for malaria elimination

Britton S ¹ , Cheng Q ² , Sutherland CJ ³ , McCarthy JS ⁴

Affiliations

¹ University of Queensland, Brisbane, Australia. [email protected]
² Australian Army Malaria Institute, Brisbane, Australia. [email protected]
³ London School of Hygiene and Tropical Medicine, London, UK. [email protected]
⁴ University of Queensland, Brisbane, Australia. [email protected]

Malar J, 2015;14:335.

PMID: 26315027 DOI: 10.1186/s12936-015-0848-3

Abstract

To detect all malaria infections in elimination settings sensitive, high throughput and field deployable diagnostic tools are required. Loop-mediated isothermal amplification (LAMP) represents a possible field-applicable molecular diagnostic tool. However, current LAMP platforms are limited by their capacity for high throughput.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms

Similar publications