Hepatotoxic constituents in the rumen of Brachiaria decumbens intoxicated sheep

Abdullah AS 1 , Lajis NH , Bremner JB , Davies NW , Mustapha W , Rajion MA

Affiliations 

  • 1 Department of Animal Science, Universiti Pertanian Malaysia, Serdang, Selangor
Vet Hum Toxicol, 1992 Apr;34(2):154-5.
PMID: 1509678

Abstract

Spectroscopic examinations of purified extracts of the rumen content of sheep intoxicated by Brachiaria decumbens revealed the presence of a mixture of sapogenins, identified as 3-spirostanols. These isomeric steroid sapogenins (C27H44O3) are believed the toxic principles in causing toxicity in sheep after feeding on B. decumbens.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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