In vivo evidence of all-trans retinoic acid inducing maturation in acute promyelocytic leukaemia

Hamidah HN 1 , Cheong SK , Ainoon O

Affiliations 

  • 1 Haematology Unit, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur
Acta Haematol., 1993;89(1):50-1.
PMID: 8480488

Abstract

All-trans retinoic acid therapy induces maturation in acute promyelocytic leukaemia. We document in vivo evidence of differentiation by all-trans retinoic acid in a case of acute promyelocytic leukaemia which was characterized by cytoplasmic vacuolations.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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