Fulltext

Variants in 6q25.1 Are Associated with Mammographic Density in Malaysian Chinese Women

Mariapun S 1 , Ho WK 2 , Kang PC 3 , Li J 4 , Lindström S 5 , Yip CH 6 Show all authors , Teo SH 7

Affiliations 

  • 1 Cancer Research Malaysia (formerly known as Cancer Research Initiatives Foundation), Subang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia. Breast Cancer Research Group, University Malaya Medical Centre, Kuala Lumpur, Malaysia
  • 2 Department of Applied Mathematics, Faculty of Engineering, University of Nottingham Malaysia Campus, Semenyih, Selangor, Malaysia
  • 3 Cancer Research Malaysia (formerly known as Cancer Research Initiatives Foundation), Subang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia
  • 4 Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • 5 Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts
  • 6 Subang Jaya Medical Centre, Selangor, Malaysia
  • 7 Cancer Research Malaysia (formerly known as Cancer Research Initiatives Foundation), Subang Jaya Medical Centre, Subang Jaya, Selangor, Malaysia. Breast Cancer Research Group, University Malaya Medical Centre, Kuala Lumpur, Malaysia. [email protected]
Cancer Epidemiol Biomarkers Prev, 2016 Feb;25(2):327-33.
PMID: 26677210 DOI: 10.1158/1055-9965.EPI-15-0746

Abstract

Mammographic density is an established risk factor for breast cancer and has a strong heritable component. Genome-wide association studies (GWAS) for mammographic density conducted in women of European descent have identified several genetic associations, but none of the studies have been tested in Asians. We sought to investigate whether these genetic loci, and loci associated with breast cancer risk and breast size, are associated with mammographic density in an Asian cohort.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

MeSH terms
Similar publications