Association of insertion/deletion polymorphism of angiotensin-converting enzyme gene with essential hypertension and type 2 diabetes mellitus in Malaysian subjects

Ramachandran V 1 , Ismail P , Stanslas J , Shamsudin N , Moin S , Mohd Jas R

Affiliations 

  • 1 Molecular Biology Laboratory, Department of Biomedical Sciences, Faculty of Medicine and Health Science, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
J Renin Angiotensin Aldosterone Syst, 2008 Dec;9(4):208-14.
PMID: 19126661 DOI: 10.1177/1470320308097499

Abstract

The deletion (D) allele of the angiotensin-converting enzyme (ACE) gene has been studied in various populations in relation to hypertension (HTN) and type 2 diabetes mellitus (T2DM) with contradictory results. This study sought to determine the association of insertion (I)/D polymorphism of the ACE gene in hypertensive and T2DM subjects in a Malaysian population.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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