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Serum neopterin is elevated in patients infected with Shigella

Singh KK 1 , Wan-Nurfahizul-Izzati W , Ismail A

Affiliations 

  • 1 Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Health Campus, 16150 Kubang Kerian, Kelantan, Malaysia. [email protected]
Gut Pathog, 2010;2(1):9.
PMID: 20727206 DOI: 10.1186/1757-4749-2-9

Abstract

Neopterin is produced by human macrophages/monocytes when stimulated with interferon-gamma. Production of neopterin is found in serum, cerebrospinal fluid (CSF) and urine of patients with infections by viruses, intracellular bacteria and parasites, autoimmune diseases, malignant tumors and patients in allograft rejection episodes.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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