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Chromosome 7 aneuploidy in clear cell and papillary renal cell carcinoma: detection using silver in situ hybridization technique

Pailoor J 1 , Rajandram R , Yap NY , Ng KL , Wang Z , Iyengar KR

Affiliations 

  • 1 Department of Surgery, Faculty of Medicine, University of Malaya Cancer Research Institute, University of Malaya, Malaysia; Centre for Kidney Disease Research, School of Medicine, University of Queensland, Australia,
Indian J Pathol Microbiol, 2013 Apr-Jun;56(2):98-102.
PMID: 24056643 DOI: 10.4103/0377-4929.118688

Abstract

Chromosome 7 aberrations in renal cell carcinoma (RCC) have been reported in papillary renal cell carcinoma (pRCC) and clear cell renal cell carcinoma (ccRCC). However, the implication of these anomalies on prognosis and survival is still unclear. RCC Chromosome 7 aberrations have commonly been detected by fluorescent in situ hybridization and chromogenic in situ hybridization but not silver in situ hybridization (SISH).

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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