Development of a recombinant non-replicating Newcastle disease virus

Cheow PS 1 , Tan TK 2 , Song AA 3 , Yusoff K 1 , Chia SL 1

Affiliations 

  • 1 Malaysia Genome and Vaccine Institute, Kajang, Malaysia
  • 2 MRC Translate Immune Discovery Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK
  • 3 Department of Microbiology, Faculty of Biotechnology & Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Malaysia
Avian Pathol, 2025 Feb;54(1):149-157.
PMID: 39318350 DOI: 10.1080/03079457.2024.2403412

Abstract

Development of nr-NDV.Reverse transfection was applied for the recovery of nr-NDV.Propagation of nr-NDV was done by sub-passaging transfected BSR T7/5 cells.Safety profile was done to prove that the nr-NDV is non-replicating.

* Title and MeSH Headings from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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