Browse publications by year: 2013

  1. Tan PC, Norazilah MJ, Omar SZ
    Obstet Gynecol, 2013 Jun;121(6):1360.
    PMID: 23812475 DOI: 10.1097/AOG.0b013e31829395ef
    MeSH terms: Female; Fluid Therapy*; Glucose/therapeutic use*; Humans; Hyperemesis Gravidarum/therapy*; Pregnancy; Sodium Chloride/therapeutic use*
  2. Citation: Guideline for Anonymous and Voluntary HIV Screening. Putrajaya: Ministry of Health, Malaysia; 2013
    MeSH terms: Humans; Malaysia; Mass Screening; Serologic Tests; HIV Infections; Practice Guidelines as Topic
  3. Wang Z, Huang S, Jia C, Liu J, Zhang J, Xu B, et al.
    Plant Cell Rep, 2013 Sep;32(9):1373-80.
    PMID: 23652818 DOI: 10.1007/s00299-013-1449-7
    KEY MESSAGE: Three tau class MaGSTs responded to abiotic stress, MaGSTF1 and MaGSTL1 responded to signaling molecules, they may play an important role in the growth of banana plantlet. Glutathione S-transferases (GST) are multifunctional detoxification enzymes that participate in a variety of cellular processes, including stress responses. In this study, we report the molecular characteristics of five GST genes (MaGSTU1, MaGSTU2, MaGSTU3, MaGSTF1 and MaGSTL1) cloned from banana (Musa acuminate L. AAA group, cv. Cavendish) using a RACE-PCR-based strategy. The predicted molecular masses of these GSTs range from 23.4 to 27.7 kDa and their pIs are acidic. At the amino acid level, they share high sequence similarity with GSTs in the banana DH-Pahang (AA group) genome. Phylogenetic analysis showed that the deduced amino acid sequences of MaGSTs also have high similarity to GSTs of other plant species. Expression analysis by semi-quantitative RT-PCR revealed that these genes are differentially expressed in various tissues. In addition, their expression is regulated by various stress conditions, including exposure to signaling molecules, cold, salinity, drought and Fusarium oxysporum f specialis(f. Sp) cubense Tropical Race 4 (Foc TR4) infection. The expression of the tau class MaGSTs (MaGSTU1, MaGSTU2 and MaGSTU3) mainly responded to cold, salinity and drought while MaGSTF1 and MaGSTL1 expressions were upregulated by signaling molecules. Our findings suggest that MaGSTs play a key role in both development and abiotic stress responses.
    MeSH terms: Cloning, Molecular; Fusarium; Glutathione Transferase/classification; Glutathione Transferase/genetics; Glutathione Transferase/metabolism*; Phylogeny; Plant Proteins/classification; Plant Proteins/genetics; Plant Proteins/metabolism*; Stress, Physiological; Gene Expression Regulation, Plant; Gene Expression Regulation, Developmental; Musa/enzymology; Musa/genetics*; Musa/growth & development
  4. Wong JY, Chen YS, Chakravarthi S, Judson JP, L SR, Er HM
    Exp Ther Med, 2013 Nov;6(5):1247-1250.
    PMID: 24223653
    Euphorbia hirta is widely used in traditional remedies and has been used cross-culturally for generations against maladies such as asthma, skin ailments and hypertension. Previous studies have demonstrated that Euphorbia hirta has antibacterial activity, and have also indicated certain antimolluscidal, antimalarial and anti-inflammatory properties, the latter of which have been suggested to be more pronounced than those of the rheumatological drug, etanercept. To date, no studies have identified the anatomical effects of this herb on the organs of test animals. This study aimed to identify the effects of Euphorbia hirta on the ultrastructure of the murine liver, kidney and aorta. A total of 32 adult male Sprague-Dawley rats were divided into four groups; three groups were fed with aqueous extracts of Euphorbia hirta at doses of 1, 10 and 50 mg/kg, respectively, every alternate day for 50 days, while one group served as a control. The animals were later sacrificed and the liver, kidney and aorta harvested for examination by electron microscopy. The aorta showed no ultrastructural changes across the groups. Renal and hepatic tissue from the treated groups demonstrated dose-dependent injuries, which showed architectural damage beginning in the nuclei and spreading outwards. Taking into consideration the properties of Euphorbia hirta that have been described in previous studies, in addition to the results from the present study, it appears that the herb may exhibit similar effects to those of the quinolone group of antibiotics. Further in-depth investigations are required into the potential effects of Euphorbia hirta, deleterious and otherwise.
  5. Raylu N, Loo J, Oei TPS
    J Cogn Psychother, 2013;27(3):297-322.
    PMID: 32759146 DOI: 10.1891/0889-8391.27.3.297
    Much research has been conducted in the treatment of gambling problems. However, very little is reported specifically on treating Asian problem gamblers. Thus, this article reviewed the general problem gambling treatment literature as well as the limited Asian problem gambling treatment literature to provide a discussion of interventions that can be used with Asian problem gamblers. The general literature showed that behavioral, cognitive, and combined cognitive behavioral treatments (CBT) have the most treatment outcome literature and appear to be the most effective in treating gambling problems. Although, pharmacotherapy also looks promising, it may be more suitable for problem gamblers with comorbid mood problems or impulsivity. Research on other forms of treatments also exists (e.g., 12-step and psychodynamic treatment approaches) but are not as robust. Only three studies have reported on the effectiveness of treatment with Asian problem gamblers. The first study is case study. The second study presents data from a treatment program for Asian problem gambling and the last one presents preliminary findings of a telephone delivered treatment program with eight Asian American gamblers. These studies support the general treatment literature in showing that CBT and pharmacotherapy have a role to play in treating Asian problem gamblers. Based on the general and Asian problem gambling treatment literature, a discussion of treatment of Asian problem gamblers is provided including the use of CBT and other forms of treatment, issues to address in treatment, and variables that can assist treatment.
    MeSH terms: Asian Americans; Cognition; Gambling; Humans; Impulsive Behavior; Telephone; Treatment Outcome
  6. Dorasamy M, Raman M, Kaliannan M
    Technol Forecast Soc Change, 2013 Nov;80(9):1834-1853.
    PMID: 32287412 DOI: 10.1016/j.techfore.2012.12.008
    Humans are increasingly being challenged with numerous forms of man-made and natural emergency situations. Emergencies cannot be prevented, but they can be better managed. The successful management of emergency situations requires proper planning, guided response, and well-coordinated efforts across the emergency management life cycle. Literature suggests that emergency management efforts benefit from well-integrated knowledge-based emergency management information systems (EMIS). This study presents a systematic review of papers pertaining to the application of knowledge-driven systems in support of emergency management that have been published in the last two decades. Our review presents two major findings. First, only limited work has been done in three EMIS-knowledge management system (KMS) subdomains: (i) definition, (ii) use, and (iii) methods. Second, only limited research has been done in embedding roles in KM systems. We highlight role alignment to the 12 fundamental roles, as called for by Turoff et al. (2004), in the context of creating dynamic systems in aid of emergency management efforts. We believe that these two findings warrant the attention of the research community.
  7. Kumar P, Narasimhan B, Ramasamy K, Mani V, Mishra RK, Majeed ABA, et al.
    Monatsh Chem, 2013;144(6):825-849.
    PMID: 32214480 DOI: 10.1007/s00706-012-0877-3
    ABSTRACT: A variety of N'-[4-[(substituted imino)methyl]benzylidene]-substituted benzohydrazides have been synthesized and evaluated for antimicrobial and anticancer potential. Results from testing of antimicrobial activity indicated the most potent antimicrobial agents had pMIC am = 1.51. The synthesized compounds were bacteriostatic and fungistatic in action. Results from evaluation of antiviral activity indicated that none of the synthesized hydrazide derivatives inhibited viral replication at sub-toxic concentrations. Results from anti-HIV screening against HIV-2 strain ROD indicated that one compound was more potent (IC 50 ≥ 1 μg/cm3) than the standard drug nevirapine (IC 50 ≥ 4 μg/cm3) and another was equipotent (IC 50 ≥ 4 μg/cm3). The most effective anticancer agent against both HCT116 and MCF7 cancer cell lines had IC 50 = 19 and 18 μg/cm3, respectively. QSAR analysis indicated the importance of Wiener index (W) and energy of the lowest unoccupied molecular orbital (LUMO) in describing the antimicrobial activity of the synthesized compounds.
  8. Citation: Garis panduan perlaksanaan komuniti Sihat Perkasa Negara (KOSPEN). Putrajaya: Ministry of Health, Malaysia; 2013
    MeSH terms: Malaysia; Patient Participation; Guidelines as Topic
  9. Ramesh MG, Sathian B, Sinu E, Kiranmai SR
    J Clin Diagn Res, 2013 Oct;7(10):2265-2267.
    PMID: 24298493 DOI: 10.7860/JCDR/2013/5889.3488
    OBJECTIVES: Psychological studies have shown that brief period of mindfulness meditation significantly improves critical cognitive skills. But, there are no studies which have assessed the effects of Brahma Kumaris Rajayoga Meditation (BKRM) practice on positive thinking and happiness in life. The present study was designed to test the hypothesis is BKRM enhances positive thinking and that essential to attain higher levels of self-satisfaction and happiness in life.

    MATERIAL AND METHODS: This study is a cross sectional comparative study which was done between Rajayoga meditators and non-meditators. This study was conducted at BKRM Centres at Manipal and Udupi in Karnataka, India. Fifty subjects were selected for this study, which included those practising BKRM in their normal routine life (n=25) and non-meditators (n=25) who were aged 42.95+/15.29 years. Self-reported Oxford happiness questionnaire (OHQ) was administered to all subjects and their happiness scores and status were assessed and compared. Items related to self-satisfaction in life were selected from the OHQ and compared between meditators and non-meditators. Participants completed self-reported OHQ, from which data of happiness status and self-satisfaction in relation to meditation duration and frequency were analyzed by descriptive statistics and test of hypothesis.

    RESULTS: Mean happiness scores of BKRM were significantly higher (p<0.001) in meditators as compared to those in non-meditators. The number of meditators experiencing happiness status were significantly higher (p<0.05) in comparison with non-meditators. Additionally, meditators scored significantly higher on self-satisfaction items (p<0.001) as compared to non-meditators. There was no correlation between age and years of meditation practice with happiness score and self-satisfaction score.

    CONCLUSION: BKRM helps in significantly increasing self-satisfaction and happiness in life by enhancing positive thinking. Irrespective of age and years of short-term or long-term meditation practice, enhanced positive thinking increases self-satisfaction and happiness in life.

  10. Tan YM, Chan SG
    Caring behaviours presented by the nurses while providing care is the essence of nursing. However, operation theatre nurses must also adhere to the nursing value in social sciences and humanities to address the patient's needs. The concern of the nurses should not only be for the basic life sustaining needs but also for physiological, psychological, socio cultural and spiritual dimension ofpatient's human responses. The purposes of this study were to determine the perception regarding caring behaviours and the level of caring among the Operation theatre nurses in Hospital Universiti Sains Malaysia. In addition, there were associations when the determination between demographic variables like genders and years of experience of the nurses in relation to their caring behaviours is necessary. It isa quantitative, descriptive survey design and 95 nurses participated in the study. The revised Wolfs Caring Behaviours Inventory was used to measure the dimensions of caring. "Professional knowledge and skill" was identified to be the highest among the five dimensions of caring that was being measured. Findings show that the nurses demonstrated a high level of caring behaviours during their course of work. However, none of the demographic factors studied were significantly associated to their caring behaviours.
    Keywords: Caring attitudes, Caring behaviours, Dimensions of caring
    MeSH terms: Adult; Cross-Sectional Studies; Empathy; Hospitals, University; Humans; Malaysia
  11. Purusothaman I, Lim PH
    Advanced nursing practice involves higher level of knowledge and skills of nurses to perform autonomous practice in clinical settings in order to meet the needs of individuals, families and communities. Advanced practice in nursing is also known as adjusting boundaries for future practice, pioneering and developing new roles of nurses in clinical practice, research and education. Advanced practice of nursing in the developed countries are recognized with different nomenclatures such as advanced nurse practitioner, clinical nurse specialist, specialized nurse practitioner, nurse practitioner, certified nurse practitioner and advanced practice registered nurse. Malaysia is one of the pioneering Asian countries to introduce clinical nurse specialist in hospital settings, which is a stepping stone for the development of advanced nursing practice.
    Keywords: Nurses in Malaysia, Clinical Nurse Practitioner, Advanced Nurse Practice
    MeSH terms: Malaysia; Advanced Practice Nursing
  12. Hashairi F, Fauzi CH, Chew KS, Nik Hisamuddin NAR
    Background: Standard Precaution (SP) is a very important health issue that has not been well-emphasized. The outcome of not following the SP is a serious problem that can lead to the blood-borne infection.
    Methods: A set of self-administered anonymous questionnaire were given to all healthcare personnel in 4 selected Emergency Department (ED), hospital in Kelantan to assess the knowledge and practice of standard precaution.
    Results: Almost half of the healthcare personnel were having a good knowledge 115 (57.8%) and good practice 156 (78.4%) towards SP. For those who did not comply with SP, complained oflackoftime as the main reason (38.5%) followed by interference with their work (29.2% ). There was no significant difference between presence of Emergency Physician or not in ED with the compliance towards SP.
    Conclusion: Though majority of the healthcare personnel in ED possessed a good level of knowledge and practice towards SP, the staff compliance should be revised regularly wherever necessary to improve the precautions.
    Keywords: Standard precaution, Emergency Department, Malaysian Nurse
    MeSH terms: Adult; Cross-Sectional Studies; Emergency Service, Hospital; Health Personnel; Hospitals, General; Hospitals, University; Humans; Health Knowledge, Attitudes, Practice; Malaysia
  13. Mustapha MS
    Adequate consumption of Omega-3 fatty acids are essential during pregnancy because they play an important role in the development offetal brain and retina. The rate of growth remains high during the first year of life. Omega-3 is converted inside the body into longer chain polyunsaturated fatty acids docosahexanoic acid (DHA) and eicosapentaenoic acid (EPA). DHA and EPA are primarily derived from fish and algae. DHA is essential for the growth and functional development of the brain in infants. DHA is also required for the maintenance of normal brain function in adults. The inclusion of adequate amount of DHA in the diet improved learning ability, whereas deficiencies of DHA are associated with deficits in learning. DHA is readily taken up by the brain in preference to other fatty acids. The turnover of DHA in the brain is very fast, more so than is generally realized. The visual acuity of healthy, full-term, formula-fed infants is increased when their formula includes DHA. However, health professionals and the general public in Malaysia may not be aware about the importance, sources or the quantities required for these essential fat components in foods. This review discusses the benefits of omega-3 consumption with particular emphasis during pregnancy and the first year of life. This review will also attempt to discuss sources of omega-3 fatty acids in Malaysia with the aim to achieve the recommended nutrient intakes foromega-3 fatty acids.
    Keywords: Omega 3 fatty acids, Lactation in Pregnancy, Sources of Omega-3 FA
    MeSH terms: Breast Feeding; Humans; Pregnancy; Fatty Acids, Omega-3
  14. Chiew L, Das U
    Stroke is the most important cause of death and foremost cause for dysfunction around the globe. As a result increase in the numberof elderly population the incidence of stroke has emerged as an important public health problem. Major developments have taken place in the field of medication for the prevention and treatment of stroke during the past decade. In spite of major interventions proposed by several organizations and the government, the present scenario of the stroke management facilities is still not promising. This article intends to investigate the health care facilities present for the elderly individuals with high risk of strokereoccurrence through proper analysis of the health system in Malaysia. The objectives are to find out evidence-based, reasonably priced and endurable measures to control the recurrences of stroke and to evaluate the outcomes of these interventions. It was noticed that in Malaysia though there many amenities for stroke patients are available but reorganizing and strengthening of few aspects such as human resource by multidisciplinary input is necessary for proper management of senior stroke patients. Moreover monitoring is essential to support patients after discharge from the hospital. The ethical variations among patient with stroke recurrence and the risk factor associated with stroke is not fully understood by healthcare workers. So, this study attempts to guide the stroke patient, their families and the health care workers to prevent stroke recurrence.
    Keywords: Stroke, Stroke Interventions, Stroke in Malaysia
    MeSH terms: Aged; Complementary Therapies; China/ethnology; Humans; Malaysia; Stroke
  15. Citation: Medical Nutrition Therapy Guideline for Type 2 Diabetes, Second Edition. Kuala Lumpur: Malaysian Dietitians' Association; 2013
    MeSH terms: Diabetes Mellitus, Type 2; Diet; Diet Therapy; Endocrinology; Humans; Malaysia; Guidelines as Topic
  16. Citation: National Diabetes Registry Report, Volume 1 (2009-2012). Putrajaya: Ministry of Health, Malaysia; 2013
    MeSH terms: Diabetes Mellitus; Epidemiology; Malaysia; Registries
  17. Abdul Latiff R, Wan Sulaiman WS, Hoesni S
    Postpartum depression is one of the major depressions experienced by women during three months after giving birth to their babies. The symptoms of this type of depression cannot be taken lightly as it affects not only the women but also the development of the babies, family harmony and functioning and can in fact harm themselves and other individuals in their surrounding. Thus, this research was conducted to identify the influence of parental stress towards postpartum depression. A total of 181 women participated in this study and they were from two groups namely married and unmarried women who just gave birth. Two instruments were used and they were the Postpartum Depression Screening Scale and the Parental Stress Index Short Form. Results obtained showed that parental stress and its dimensions were significantly correlated with postpartum depression. In addition, maternal stress and difficult child characteristics were significant predictors of postpartum depression. Findings also showed that there were significant differences of parental stress and its dimensions between married and unmarried women who just gave birth. These findings imply the importance of coping with parental stress to prevent women from experiencing postpartum depression.
    Keywords Postpartum Depression · Parental Stress · Child Characteristics · Regression
    MeSH terms: Ambulatory Care Facilities; Depression; Humans; Malaysia; Maternal-Child Health Centers; Stress, Psychological; Parenting; Depression, Postpartum
  18. Sorketti EA, Zuraida NZ, Habil MH
    Int Psychiatry, 2013 May;10(2):45-47.
    PMID: 31507730
    Understanding the way in which people seek care for mental disorders is important for planning services, training and referral mechanisms. Pathways to care fall broadly into three categories: via primary care physicians; via native healers; and via patient choice (patients can have direct access to mental health professionals). The pattern and nature of access to service in low-income countries are different from those in high-income countries. In many societies, deep-seated cultural beliefs on the part of patients and families about the causes of mental disorders are a major barrier to the receipt of modern psychiatric care.
    MeSH terms: Mental Disorders; Humans; Income; Mental Health; Poverty; Psychotherapy; Referral and Consultation; Developed Countries; Physicians, Primary Care
  19. Mohamad I
    J Neurosci Rural Pract, 2013 Aug;4(Suppl 1):S97-8.
    PMID: 24174812
  20. Aziz Z, Cullum N, Flemming K
    PMID: 23450536 DOI: 10.1002/14651858.CD002933.pub5
    BACKGROUND: Leg ulceration is a common, chronic, recurring condition. The estimated prevalence of leg ulcers in the UK population is 1.5 to 3 per 1000. Venous ulcers (also called stasis or varicose ulcers) comprise 80% to 85% of all leg ulcers. Electromagnetic therapy (EMT) is sometimes used as a treatment to assist the healing of chronic wounds such as venous leg ulcers.

    OBJECTIVES: To assess the effects of EMT on the healing of venous leg ulcers.

    SEARCH METHODS: For this third update, we searched The Cochrane Wounds Group Specialised Register (searched 12 November 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 10); Ovid MEDLINE (2011 to November Week 1 2012); Ovid MEDLINE (In-Process & Other Non-Indexed Citations, November 12, 2012); Ovid EMBASE (2011 to 2012 Week 45); and EBSCO CINAHL (2011 to 9 November 2012).

    SELECTION CRITERIA: Randomised controlled trials comparing EMT with sham-EMT or other treatments.

    DATA COLLECTION AND ANALYSIS: At least two review authors independently scrutinised search results and obtained full reports of potentially eligible studies for further assessment. We extracted and summarised details of eligible studies using a data extraction sheet, and made attempts to obtain missing data by contacting study authors. A second review author checked data extraction, and we resolved disagreements after discussion between review authors.

    MAIN RESULTS: Three randomised controlled trials (RCTs) of variable quality involving 94 people were included in the original review; subsequent updates have identified no new trials. All the trials compared the use of EMT with sham-EMT. In the two trials that reported healing rates; one small trial (44 participants) reported that significantly more ulcers healed in the EMT group than the sham-EMT group however this result was not robust to different assumptions about the outcomes of participants who were lost to follow up. The second trial that reported numbers of ulcers healed found no significant difference in healing. The third trial was also small (31 participants) and reported significantly greater reductions in ulcer size in the EMT group however this result may have been influenced by differences in the prognostic profiles of the treatment groups.

    AUTHORS' CONCLUSIONS: There is no high quality evidence that electromagnetic therapy increases the rate of healing of venous leg ulcers, and further research is needed.

    MeSH terms: Humans; Varicose Ulcer/therapy*; Wound Healing*; Randomized Controlled Trials as Topic; Magnetic Field Therapy/methods*
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