MyMedR

Factors associated with poor patient compliance with antituberculosis therapy in Northwest Perak, Malaysia

Chuah SY

Tubercle, 1991 Dec;72(4):261-4.

A retrospective study of factors associated with poor patient compliance with antituberculosis therapy was conducted in Taiping, Perak. 219 patients were studied. Male patients and hospital referrals were significantly more likely to default. Patients with tuberculous lymphadenitis alone had a greater rate of default, but this just failed to reach significance (0.05 less than p less than 0.10). Six of 7 male hospital referrals with tuberculous lymphadenitis alone defaulted. Patients treated as outpatients from the start were more compliant. Housewives were also highly compliant. It was noticed that patients who defaulted tended to do so during early stages of treatment.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Tuberculous cervical lymphadenitis in a patient with suspected neck recurrence

Yong DJ, Iskandar H, Razif MY

Chin Med J (Engl), 2012 May;125(9):1667-8.

PMID: 22800842

The significance of metastastic disease in the cervical lymph nodes has long been appreciated. The rich lymphatics of the upper aerodigestive tract explained the high incidence of cervical metastasis, occasional bilaterally spread. Even with appropriate treatment, cervical recurrences do occur. Nonetheless, with the resurgence of tuberculosis, the differential of tuberculous cervical lymphadenitis should be excluded. Appropriate modalities should be employed in making the appropriate diagnosis possible.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Fulltext An evidence-based clinical pathway for the diagnosis of tuberculous lymphadenitis: A systematic review

Sivaratnam L, Nawi AM, Abdul Manaf MR

Int J Mycobacteriol, 2020 6 1;9(2):107-115.

PMID: 32474531 DOI: 10.4103/ijmy.ijmy_207_19

To achieve the World Health Organization end TB Strategy, early detection, and prompt treatment of not only pulmonary but also extrapulmonary tuberculosis (EPTB) should be achieved. The most common EPTB is tuberculous lymphadenitis, and the diagnosis is typically time-consuming. This review aimed to identify the best diagnostic pathway for preventing treatment delay and thus further complications. A systematic keyword search was done using four databases and other relevant publications and using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart to search for relevant articles that met the inclusion criteria. The quality of the articles was assessed using Newcastle-Ottawa Scale, and the articles were summarized based on the test for diagnosing tuberculous lymphadenitis. A total of ten articles were included for the synthesis of results, which compared the sensitivity and specificity of each diagnostic test for tuberculous lymphadenitis. The most promising test is the Xpert Mycobacterium tuberculosis/RIF, which has high sensitivity and specificity, but costs much more in comparison to the other tests. An ideal diagnostic method should include the combination of relevant patient history, clinical examination, and laboratory and radiological testing to avoid delays in treatment, misdiagnosis, and further complications.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Tuberculous lymphadenitis at Penang General Hospital, Malaysia

Khan AH, Sulaiman SA, Muttalif AR, Hassali MA, Khan TM

Med Princ Pract, 2011;20(1):80-4.

PMID: 21160220 DOI: 10.1159/000319764

To evaluate the incidence, treatment and clinical outcomes of tuberculous (TB) lymphadenitis at Penang General Hospital, Malaysia.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Fulltext Multi-organ involvement of tuberculosis--case report of an atypical presentation

Simon GK, Ahmad N

Med J Malaysia, 1990 Mar;45(1):78-80.

PMID: 2152074

A case involving tuberculosis of multiple organs and mimicking carcinoma in several respects is presented.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Fulltext Treatment outcomes and risk factors of extra-pulmonary tuberculosis in patients with co-morbidities

Khan AH, Sulaiman SAS, Laghari M, Hassali MA, Muttalif AR, Bhatti Z, et al.

BMC Infect Dis, 2019 Aug 05;19(1):691.

PMID: 31382889 DOI: 10.1186/s12879-019-4312-9

BACKGROUND: Extra-pulmonary tuberculosis (EPTB) represents about 14% of all cases of tuberculosis (TB) in Malaysia. The aims of the study include evaluation of socio-demographic factors, clinical manifestations, co-morbidities among patients with EPTB and their treatment outcomes.

METHODS: A retrospective study was conducted to recognize the epidemiology facts of EPTB. Individual data for EPTB patients were collected from TB registers, laboratory TB registers, treatment cards and TB medical personal files into a standardized study questionnaire. Crude (COR) and adjusted odds ratios (AOR) and 95% confidence intervals (CI) were determined to assess the risk factors for EPTB and unsuccessful treatment outcomes.

RESULTS: There were 1222 EPTB patients presenting 13.1% of all TB cases during 2006-2008. Pleural effusion and lymph node TB were the most frequent types and accounted for 45.1% of all EPTB cases among study participants. Treatment success rate was 67.6%. The best treatment completion rates were found in children ≤15 years (0.478 [0.231-1.028]; p = 0.05). On multivariate analysis, age group 56-65 years (1.658 [1.157-2.376]; p = 0.006), relapse cases (7.078 [1.585-31.613]; p = 0.010), EPTB-DM (1.773 [1.165-2.698]; p = 0.008), patients with no formal (2.266 [1.254-4.095]; p = 0.001) and secondary level of education (1.889 [1.085-3.288]; p = 0.025) were recorded as statistically positive significant risk factors for unsuccessful treatment outcomes. Patients at the risk of EPTB were more likely to be females (1.524 [1.311-1.746]; p

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

Diagnostic challenges in tuberculous otitis media

Tang IP, Prepageran N, Ong CA, Puraviappan P

J Laryngol Otol, 2010 Aug;124(8):913-5.

PMID: 20426886 DOI: 10.1017/S0022215110000265

To demonstrate the different clinical presentations of tuberculous otitis media and the management of selected cases.

Matched MeSH terms: Tuberculosis, Lymph Node/drug therapy

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