MyMedR

Fulltext Draft Genome Sequence of Yellow Pigmented Jeotgalibacillus alimentarius JY-13T, the First Halophile Strain of the Genus Jeotgalibacillus

Yaakop AS, Chan KG, Gan HM, Goh KM

Genome Announc, 2015;3(5).

PMID: 26494670 DOI: 10.1128/genomeA.01224-15

Jeotgalibacillus alimentarius JY-13(T) (=KCCM 80002(T) = JCM 10872(T)) is a moderate halophile. In 2001, this was the first strain of the newly proposed Jeotgalibacillus genus. The draft genome of J. alimentarius was found to consist of 32 contigs (N50, 315,125 bp) with a total size of 3,364,745 bp. This genome information will be helpful for studies on pigmentation as well as applications for this bacterium.

Matched MeSH terms: Pigmentation Disorders

Heterochromia iridis: More than beautiful eyes

Saniasiaya J

Postgrad Med J, 2020 11;96(1141):721.

PMID: 32144119 DOI: 10.1136/postgradmedj-2020-137621

Matched MeSH terms: Pigmentation Disorders*

Incontinentia pigmenti

TEIK KO, SMITH GD, SUN CE

Med J Malaya, 1959 Sep;14:17-26.

PMID: 13837285

Matched MeSH terms: Pigmentation Disorders*

Fulltext Hypomelanosis of Ito

Choo KE

Med J Malaysia, 1983 Jun;38(2):167-9.

PMID: 6621451

Two cases of Hypomelanosis of Ito are described; presenting with depigmented whorl-like, zig-zag, bizzare cutaneous manifestations associated with central nervous system disorders.

Matched MeSH terms: Pigmentation Disorders*

Melanonychia striata: clarifying behind the Black Curtain. A review on clinical evaluation and management of the 21st century

Leung AKC, Lam JM, Leong KF, Sergi CM

Int J Dermatol, 2019 Nov;58(11):1239-1245.

PMID: 31006857 DOI: 10.1111/ijd.14464

Melanonychia striata is characterized by a tan, brown, or black longitudinal streak within the nail plate that runs from the proximal nail fold to the distal part of the nail plate. Melanonychia striata is due to increased activity of melanocytes or melanocytic hyperplasia in the nail matrix with subsequently increased melanin deposition in the nail plate. The most common cause of melanonychia striata associated with melanocytic activation is ethnic melanonychia which occurs in dark-skinned individuals. Other causes of melanonychia striata related to melanocytic activation include pregnancy, chronic local trauma, infections, medications, dermatological disorders, endocrine disorders, alkaptonuria, hemochromatosis, porphyria, graft-vs-host disease, Peutz-Jeghers syndrome, and Laugier-Hunziker syndrome. Causes of melanonychia striata associated with melanocytic hyperplasia include nail matrix melanocytic nevus, nail lentigo, and nail apparatus/subungual in situ and invasive melanoma. In most cases, melanonychia striata is a benign condition, especially in children. Consequently, most investigators advocate a wait-and-see approach. Nail apparatus/subungual melanoma should be suspected if there is an abrupt onset after middle age, personal or family history of melanoma, rapid growth, darkening of a melanonychia band, pigment variegation, blurry lateral borders, irregular elevation of the surface, a bandwidth >3 mm, proximal widening, associated nail plate dystrophy, single rather than multiple digit involvement, and periungual spread of pigmentation onto the adjacent cuticle and/or proximal and/or lateral nail folds (Hutchinson sign). Prolonged follow-up is mandatory for early detection of possible malignant changes.

Matched MeSH terms: Pigmentation Disorders/diagnosis*; Pigmentation Disorders/pathology; Pigmentation Disorders/therapy

Fulltext The use of r value

Yadav H

Med J Malaysia, 1985 Jun;40(2):143-4.

PMID: 3834287

Matched MeSH terms: Pigmentation Disorders/diagnosis

Motor control on gait performance among individuals with lower crossed syndrome: A scoping review

Zahari Z, Naga DNA, Bukry SA

Med J Malaysia, 2024 Mar;79(Suppl 1):168-175.

PMID: 38555902

INTRODUCTION: Lower Cross Syndrome (LCS) is a prevalent condition that manifests as muscular tension due to the asymmetry in the strength of the lower extremity muscles. This imbalance could be due to the tautness of the iliopsoas, rectus femoris, tensor fascia latae, adductor group, gastrocnemius, and soleus muscles. LCS causes a postural imbalance in the individual, which triggers low back pain (LBP). When LCS is present alongside LBP, may cause the upper body to sway more in the transverse plane and at the lumbar level, making walking and termination of gait (GT) more difficult. However, the evidence of motor control and gait performance is scarce with inconclusive findings. Thus, this study aimed to review motor control on gait performance among individuals with lower crossed syndrome. This review is conducted to determine the motor control on gait performance in patients with LCS and how the conditions affect gait.

MATERIALS AND METHODS: The databases Google Scholar, Science Direct, ResearchGate, PubMed, and Scopus were searched to identify potentially relevant documents. The keywords used for the search included "motor control" OR "motor learning" OR" core stability" AND "lower crossed syndrome" AND "gait". The search includes articles published between 1970 and 2022 and written in English. It is excluded when the paper is not a full-text article. After finding the articles, the information was extracted, including author, year of publication, country, objective, type of study, and motor control analysis summary.

RESULTS: There were 107 articles retrieved from the search. but only seventeen articles were included for analysis. The finding demonstrates that LCS may associate with LBP and reduces the motor control of the core muscle stability which indirectly influences gait performance.

CONCLUSIONS: This study suggests that individuals with LCS will have an alteration in their gait. However, there is still insufficient information on motor control in gait performance among lower crossed syndrome. Further research is needed to find what factors that may contribute to the adaptation of motor control in gait among LCS population.

Matched MeSH terms: Pigmentation Disorders*

Lichen amyloidosis

Dutt AK

Med J Malaya, 1969 Dec;24(2):164-5.

PMID: 4244146

Matched MeSH terms: Pigmentation Disorders

Fulltext Designation of a neotype for Enteromiuspallidus (Smith, 1841), an endemic cyprinid minnow from the Cape Fold Ecoregion, South Africa

Martin MB, Chakona A

Zookeys, 2019;848:103-118.

PMID: 31160881 DOI: 10.3897/zookeys.848.32211

Enteromiuspallidus was described by Smith in 1841 without a designated type specimen for the species. Herein, we designate a specimen from the Baakens River system as a neotype for E.pallidus and provide a thorough description for this species to facilitate ongoing taxonomic revisions of southern African Enteromius. Enteromiuspallidus can be distinguished from the other minnows in the "goldie barb group" by having an incomplete lateral line, lack of distinct chevron or tubular markings around lateral line pores, absence of a distinct lateral stripe, absence of wavy parallel lines along scale rows and lack of black pigmentation around the borders of the scales. We provide mtDNA COI sequences for the neotype and an additional specimen from the Baakens River as DNA barcodes of types and topotypes are a fundamental requirement for further taxonomic studies.

Matched MeSH terms: Pigmentation Disorders

Temperature dependency of aqueous biphasic systems: an alternative approach for exploring the differences between Coulombic-dominated salts and ionic liquids

E Silva FA, Pereira JFB, Kurnia KA, Ventura SPM, Silva AMS, Rogers RD, et al.

Chem Commun (Camb), 2017 Apr 27.

PMID: 28447082 DOI: 10.1039/c7cc02294h

Herein we propose an alternative way to distinguish ionic liquids from Coulombic-dominated salts, based not on their upper limit melting temperature (100 °C), but on the trend of their phase-forming abilities to create aqueous biphasic systems as a function of temperature, in which a wider plethora of interactions can be appraised.

Matched MeSH terms: Pigmentation Disorders

Fulltext Baseline coral disease surveys within three marine parks in Sabah, Borneo

Miller J, Sweet MJ, Wood E, Bythell J

PeerJ, 2015;3:e1391.

PMID: 26732905 DOI: 10.7717/peerj.1391

Two of the most significant threats to coral reefs worldwide are bleaching and disease. However, there has been a scarcity of research on coral disease in South-East Asia, despite the high biodiversity and the strong dependence of local communities on the reefs in the region. This study provides baseline data on coral disease frequencies within three national parks in Sabah, Borneo, which exhibit different levels of human impacts and management histories. High mean coral cover (55%) and variable disease frequency (mean 0.25 diseased colonies m(-2)) were found across the three sites. Highest disease frequency (0.44 diseased colonies per m(2)) was seen at the site closest to coastal population centres. Bleaching and pigmentation responses were actually higher at Sipadan, the more remote, offshore site, whereas none of the other coral diseases detected in the other two parks were detected in Sipadan. Results of this study offer a baseline dataset of disease in these parks and indicate the need for continued monitoring, and suggest that coral colonies in parks under higher anthropogenic stressors and with lower coral cover may be more susceptible to contracting disease.

Matched MeSH terms: Pigmentation Disorders

Fulltext Adeno-tonsillar hypertrophy as a cause of sleep apnoea syndrome

Ravindran VK

Med J Malaysia, 1983 Jun;38(2):164-6.

PMID: 6621450

An interesting case is described here in which partial airway obstruction resulted in sleep apnoea and which was relieved by adeno-tonsillectomy. Enlarged tonsils and adenoids causing upper airway obstruction represent one facet of a continuum of hypoventilation - sleep disorders and clinical examination with x-rays will help in determining patients at risk of developing these syndromes.

Matched MeSH terms: Pigmentation Disorders*

Tyrisonase inhibition and melanin reduction of human melanocytes (HEMn-MP) using Anacardium occidentale L extract

Abdul Gaffar R, Abdul Majid FA, Sarmidi MR

Med J Malaysia, 2008 Jul;63 Suppl A:100-1.

PMID: 19025004

Cashew (Anacardium occindentale L) leaves extract (CLE) has potential as tyrosinase inhibitor that can be used for therapeutic in pigmentation problem. This study investigates the real potential of CLE to inhibit tyrosinase and melanin reduction using human epidermal melanocytes. The extracts were exposed to the human melanocytes for more than 24 hours. The CLE extract exhibited potential as tyrosinase inhibitor, reduced melanin and high in antioxidant activity relative to commercial extract of Emblica sp.

Matched MeSH terms: Pigmentation Disorders/drug therapy*

Ficus deltoidea (Mas cotek) extract exerted anti-melanogenic activity by preventing tyrosinase activity in vitro and by suppressing tyrosinase gene expression in B16F1 melanoma cells

Oh MJ, Hamid MA, Ngadiran S, Seo YK, Sarmidi MR, Park CS

Arch. Dermatol. Res., 2011 Apr;303(3):161-70.

PMID: 20981431 DOI: 10.1007/s00403-010-1089-5

Ficus deltoidea (Mas cotek) water extract has been widely used for woman health in Malaysia. Our investigation focused to identify anti-melanogenic efficacy of F. deltoidea since it has been known to have strong anti-oxidant activities. Anti-melanogenic effect of F. deltoidea extract was analyzed using cultured B16F1 melanoma cells. Cytotoxicity of the extract was measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and determined the highest concentration of the extract that did not affect cell viability as 0.1% (w/v). α-MSH-induced melanin synthesis was significantly inhibited with dose-dependent manner by treatment of F. deltoidea leave extract, which was comparable to that of kojic acid. The extract directly inhibited mushroom tyrosinase activity and intracellular tyrosinase activity of B16F1 as well. The inhibition of intracellular tyrosinase activity was found to be exerted at the protein expression level when analyzed by immunoblot and tyrosinase zymography. The expression of microphthalmia-associated transcription factor (MITF) was also reduced by the F. deltoidea extract. In conclusion, F. deltoidea extract has strong anti-melanogenic activity that is exerted by direct inhibition of tyrosinase enzyme activity and by down-regulation of the expression of genes involved in the melanogenesis pathways. Collectively, data shown in this study strongly suggest that F. deltoidea extract has potential to be used as a novel depigmenting agent for cosmetics.

Matched MeSH terms: Pigmentation Disorders/drug therapy*

The prevalence of tongue lesions in Malaysian dental outpatients from the Klang Valley area

Koay CL, Lim JA, Siar CH

Oral Dis, 2011 Mar;17(2):210-6.

PMID: 20796228 DOI: 10.1111/j.1601-0825.2010.01724.x

OBJECTIVES: To determine the prevalence of tongue lesions in Malaysian dental outpatients from the Klang Valley area.
SUBJECTS AND METHODS: A cross sectional study was conducted on 600 Malaysian outpatients (257 men, 343 women, mean age, 37.7 years) attending the Primary Dental Care Unit at the Faculty of Dentistry, University of Malaya. Demographic and medical data were recorded for all respondents.
RESULTS: One hundred eighty-one patients (30.2%) (81 men, 100 women, mean age 42.0 years) were diagnosed with at least one tongue lesion (n = 207) at the time of examination. Of these, 24 patients (4%) had two or more tongue lesions present synchronously. Seven different lesions were diagnosed: fissured tongue (13.8%), crenated tongue (7.8%), pigmented tongue (6.2%), geographic tongue (2.2%), ankyloglossia (1.7%), hairy tongue (1.0%) and median rhomboid glossitis (0.2%). Their racial prevalences were Malays (n = 65, 10.8%), Indians (n = 62, 10.3%), Chinese (n = 53, 8.8%) and other race (n = 1, 0.2%). A significant relationship was observed between crenated tongue and race; between four types of tongue lesions (fissured tongue, geographic tongue, crenated tongue and pigmented tongue) and age; and between fissured tongue and gender (P

Matched MeSH terms: Pigmentation Disorders/epidemiology

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