MyMedR

Fulltext Cerebral Venous Thrombosis following COVID-19 Vaccination

Kow CS, Hasan SS

J Stroke Cerebrovasc Dis, 2021 Oct;30(10):105866.

PMID: 34045111 DOI: 10.1016/j.jstrokecerebrovasdis.2021.105866

Matched MeSH terms: Intracranial Thrombosis*

An uncommon mediastinal cyst with a rare neurologic consequence

Sivalingam S, Qureshi AU, Chern LM, Latiff HA

Ann Thorac Surg, 2014 Apr;97(4):e93-5.

PMID: 24694456 DOI: 10.1016/j.athoracsur.2013.12.060

Enteric cysts are uncommon posterior mediastinal cysts, usually presenting with respiratory symptoms in infancy. We present a rare case of posterior mediastinal enteric cyst extending from below the diaphragm and perforating into the left atrium, causing a thromboembolic cerebral infarct in a 5-year-old boy.

Matched MeSH terms: Intracranial Thrombosis/etiology*

Fulltext Mechanical Thrombectomy for Life-Threatening Cerebral Venous Thrombosis: A Case Report

Lau KF, Toh TH, Kadir KAA, Tai MS, Tan KS

Case Rep Neurol, 2020 12 14;12(Suppl 1):63-69.

PMID: 33505274 DOI: 10.1159/000507343

Cerebral venous thrombosis (CVT) is a rare cause of stroke worldwide with a wide range of clinical presentations. Anticoagulation therapy has been regarded as the first line of management of CVT to prevent the progression of thrombosis and to re-establish the venous flow. We present a case of severe CVT who did not respond to conventional anticoagulation therapy but responded well to mechanical thrombectomy (MT). This report highlights the features of CVT to consider for early MT.

Matched MeSH terms: Intracranial Thrombosis

Fulltext Cerebral venous thrombosis as an initial manifestation of acute myeloid leukemia

Tang ASO, Yeo ST, Law WC, Chew LP

Oxf Med Case Reports, 2019 Jan;2019(1):omy118.

PMID: 30697435 DOI: 10.1093/omcr/omy118

Cancer-associated thromboembolism is not an uncommon complication in patients with malignancies. No study has reported the occurrence of thromboembolism prior to the diagnosis of acute myeloid leukemia (AML). Most reports are anectodal and data are scarce on this subject. In this report, we present a case of extensive cerebral venous thrombosis (CVT) that was detected a few weeks before the diagnosis of AML, in which case the patient responded well to chemotherapy and anticoagulation.

Matched MeSH terms: Intracranial Thrombosis

Fulltext Predictors of functional outcome in patients with stroke thrombolysis in a tertiary hospital in Malaysia

Tai MLS, Goh KJ, Kadir KAA, Zakaria MI, Yap JF, Tan KS

Singapore Med J, 2019 May;60(5):236-240.

PMID: 30488077 DOI: 10.11622/smedj.2018150

INTRODUCTION: Intravenous (IV) thrombolysis with alteplase (rt-PA) is effective in ischaemic stroke. The primary objective was to evaluate predictors of functional outcome in acute ischaemic stroke (AIS) patients treated with IV rt-PA. The secondary objective was to assess the outcome with the modified Rankin scale (mRS). We also examined the predictive value of the Totaled Health Risks in Vascular Events (THRIVE) score.

METHODS: AIS patients treated with IV rt-PA from February 2012 to August 2016 were recruited. Demographic data, National Institutes of Health Stroke Scale (NIHSS) scores, timing and neuroradiological findings were recorded. Patients received a dose of 0.9 mg/kg IV rt-PA within 4.5 hours of symptom onset. mRS score was evaluated at discharge and three months, and good and poor clinical outcomes were defined as scores of 0-2 and 3-6, respectively. Baseline THRIVE scores were assessed.

RESULTS: 36 patients received IV rt-PA. 20 (55.6%) patients had an mRS score of 0-2 at three months. Based on THRIVE score, 86.1% had a good or moderately good prognosis. On univariate analysis, poor outcome was associated with NIHSS score before rt-PA (p = 0.03), THRIVE score (p = 0.02), stroke subtype (p = 0.049) and diabetes mellitus (DM; p = 0.06). Multiple logistic regression showed that outcome was significantly associated with NIHSS score before rt-PA (p = 0.032) and DM (p = 0.010).

CONCLUSION: Our newly developed Malaysian IV rt-PA service is safe, with similar outcomes to the published literature. Functional outcome after thrombolysis was associated with baseline NIHSS score and DM.

Matched MeSH terms: Intracranial Thrombosis/drug therapy*

Fulltext Cerebral venous thrombosis: an unusual cause of complex ophthalmoplegia in an elderly man

Ng, Benjamin Han Sim, Prakash Supahiah, Goh, Siew Yuen

Borneo Journal of Medical Sciences, 2021;15(1):45-48.

MyJurnal

Cerebral venous thrombosis (CVT) is a neurological condition occurring because of thrombosis involving the cerebral venous sinuses. This case report is an unusual clinical manifestation of cerebral venous thrombosis in a 76-year-old Chinese man who presented with restricted eye movement and double vision. Despite extensive investigation, there was no better explanation for his clinical symptom and sign apart from cerebral venous thrombosis which was confirmed by magnetic resonance venography (MRV) of the brain. Once cerebral venous thrombosis was diagnosed, he was initiated on anticoagulation and discharged with oral warfarin. This case emphasizes the need to consider cerebral venous thrombosis as one of the rare causes of complex ophthalmoplegia especially when typical cardiovascular risk factors are lacking in an individual.

Matched MeSH terms: Intracranial Thrombosis

Fulltext Cerebral venous thrombosis in evan’s syndrome: an unusual presentation

Cheng, M.H., Norzila, T.A.B.

International Medical Journal Malaysia, 2016;15(2):85-87.

MyJurnal

Cerebral Venous Thrombosis in patients with Evan’s Syndrome of autoimmune hemolytic anemia is rare. The
common neurological symptoms are headaches, vision loss, dyslexia without agraphia, motor aphasia,
unilateral upper limb weakness and papilloedema. We present a case report of a lady with a known case of
Evan’s Syndrome whom presented with severe anemia and unilateral right sided hemiparesis with right facial
weakness. Plain and Contrast enhanced CT brain showed bilateral high parietal white matter edema with
venous thrombosis in the right transverse and superior sagittal venous sinuses. At the time of the diagnosis,
she was in hematological remission.

Matched MeSH terms: Intracranial Thrombosis

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