Rheumatoid arthritis (RA) is thought to be a 'recent' disease in that descriptions of it were only noted in the 17th century. However, a study of paintings would suggest that RA could have been present as early as the 15th century, when artists started to paint the human body accurately rather than figuratively. Thus, it was possible to deduce from their paintings the occurrence of various medical conditions. If present, RA with its typical finger deformities should be apparent. This review discusses the known occurrences of RA-type deformities in paintings and places this in the context of the origins of the disease.
Throughout human history, doctors and healers have gathered and refined the knowledge inherited from the previous generations. Different methods of effective therapy have been designed during various historical periods; when each was developed, it was considered "modern scientific medicine" for their time. Mankind has gone through natural and social disasters and survived; hence, history has proved there was no time when medical knowledge was erroneous or ineffective. Classic medicine has grown to be divided into narrow, specialized branches, causing it to lose its holistic approach and general view on health, sickness and therapeutic methods. Many of traditional medicine's effective methods have been forgotten and removed from the mainstream medicine. It would be good for modern medical education to incorporate the general knowledge of historically effective therapeutic modalities and study practical cases. Medical students should be taught how to choose a "good method" or "good medicine" independent of when that method or remedy was discovered. However, he has to keep in mind the primary goal of medicine: "I will use treatment to help the sick according to my ability and judgment…"(from Hippocratic Oath).
Over the past 50 years, a variety of surgical procedures have been advocated for the treatment of operable breast cancer, ranging from local excision to supraradical mastectomy. Today, the surgical treatment of breast cancer remains highly contentious. We review the historical development of breast cancer surgery and analyse the available evidence supporting conservative procedures. We also express our opinions on the treatment of early breast cancer and illustrate the changing patterns of surgery with our experience at National University Hospital.
The reconstruction of fire history is essential to understand the palaeoclimate and human history. Polycyclic aromatic hydrocarbons (PAHs) have been extensively used as a fire marker. In this work, the distribution of PAHs in Borneo peat archives was investigated to understand how PAHs reflect the palaeo-fire activity. In total, 52 peat samples were analysed from a Borneo peat core for the PAH analysis. Pyrogenic PAHs consist of 2-7 aromatic rings, some of which have methyl and ethyl groups. The results reveal that the concentration of pyrogenic PAHs fluctuated with the core depth. Compared to low-molecular-weight (LMW) PAHs, the high-molecular-weight (HMW) PAHs had a more similar depth variation to the charcoal abundance. This finding also suggests that the HMW PAHs were mainly formed at a local fire near the study area, while the LMW PAHs could be transported from remote locations.