Displaying publications 1 - 20 of 78 in total

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  1. Blood gastrin and pepsinogen responses of native village goats in Malaysia to infection with Haemonchus contortus
    Fox MT, Jacobs DE, Sani RA
    Ann Trop Med Parasitol, 1991 Apr;85(2):263-7.
    PMID: 1796870
    Blood gastrin and pepsinogen responses of native village goats in Malaysia to a single dose of 10,500 infective Haemonchus contortus larvae were investigated. Both blood values were significantly elevated within a week of infection and exhibited a highly significant correlation during the study. The magnitude of the blood gastrin response was, however, significantly greater than that of pepsinogen during the period that both blood values were elevated. It is suggested that blood gastrin assay may be of particular value in the diagnosis of chronic haemonchosis in animals harbouring relatively light worm burdens.
    Matched MeSH terms: Goat Diseases/blood*; Goat Diseases/diagnosis
  2. Experimental infection of dexamethasone-treated goats with Pasteurella haemolytica A2
    Zamri-Saad M, Jasni S, Nurida AB, Sheikh-Omar AR
    Br. Vet. J., 1991 Nov-Dec;147(6):565-8.
    PMID: 1777800
    Sixteen goats either subjected to transport stress or without transport stress were treated with dexamethasone for 3 days prior to infection with P. haemolytica serotype A2 intranasally. The transport-stressed and dexamethasone-treated goats in the first group had various degrees of pulmonary lesions and the organism was re-isolated from the nasal cavity, lymph nodes and lungs. None of the goats treated with dexamethasone only were infected with P. haemolytica and had no lesions of pneumonic pasteurellosis. Treatment with dexamethasone alone failed to induce experimental infection by P. haemolytica except in combination with another stress factor.
    Matched MeSH terms: Goat Diseases/etiology*; Goat Diseases/pathology
  3. The role of concurrent haemonchosis in the development of pneumonic pasteurellosis in goats
    Zamri-Saad M, Subramaniam P, Sheikh-Omar AR, Sani RA, Rasedee A
    Vet Res Commun, 1994;18(2):119-22.
    PMID: 7975196
    Matched MeSH terms: Goat Diseases/microbiology*; Goat Diseases/parasitology*
  4. Isolation of Pasteurella haemolytica from the nasal cavity of goats
    Jasni S, Zamri-Saad M, Mutalib AR, Sheikh-Omar AR
    Br. Vet. J., 1991 Jul-Aug;147(4):352-5.
    PMID: 1913132
    Twenty transport-stressed goats were divided into two groups. The first group was further stressed with steroid. Pasteurella haemolytica was found at various sites in the nasal cavity of goats in this group as early as 2 weeks post-transportation. The successful isolations continued consistently with more goats having pure growth of P. haemolytica at later stages. Mild catarrh rhinitis, loss of epithelial cilia and erosions were the main lesions observed in the nasal cavity. Goats in the second group that were not given steroid injections had inconsistent bacterial isolation and less severe pathological lesions.
    Matched MeSH terms: Goat Diseases/microbiology*
  5. Contagious ecthyma: how serious is the disease worldwide?
    Lawan Z, Bala JA, Bukar AM, Balakrishnan KN, Mangga HK, Abdullah FFJ, et al.
    Anim Health Res Rev, 2021 06;22(1):40-55.
    PMID: 34016216 DOI: 10.1017/S1466252320000018
    Contagious ecthyma (CE) is an infectious disease of small ruminants caused by a parapoxvirus of family Poxviridae subfamily Chordopoxvirinae. The disease is obviously distinguished by an establishment of scabby lesions and ulcerative formation on less hairy areas including muzzle, ears, nostril, and sometimes on genitalia. The disease is endemic in sheep and goats. The virus is transmissible to other ruminants and is a public health concern in humans. Although the disease is known as self-limiting, it may cause a significant economic threat and financial losses due to lower productivity in livestock production. Information with regard to the risk of the disease and epidemiology in most parts of the world is underreported. This paper aims to provide relevant information about the epidemiology of CE in selected regions of Europe, South America, North America, Asia, Africa, and Australia. An in-depth comprehension of virus infection, diagnoses, and management of the disease will enable farmers, researchers, veterinarians, abattoir workers, health personnel, and border controllers to improve their measures, skills, and effectiveness toward disease prevention and control, toward reducing unnecessary economic loss among farmers. A herd health program for significant improvement in management and productivity of livestock demands a well planned extension program that ought to encourage farmers to equip themselves with adequate skills for animal healthcare.
    Matched MeSH terms: Goat Diseases*
  6. The goat as a model for studies of pneumonic pasteurellosis caused by Pasteurella multocida
    Zamri-Saad M, Effendy WM, Maswati MA, Salim N, Sheikh-Omar AR
    Br. Vet. J., 1996 Jul;152(4):453-8.
    PMID: 8791853
    A model of pneumonic pasteurellosis has been established in goats using Pasteurella multocida harvested from pneumonic lungs of goats (types A and D), rabbits (type A) and sheep (type D). The resultant infections were acute, subacute or chronic. The gross and histological lesions of the subacute and chronic infections were typical of pneumonic pasteurellosis. P. multocida type D produced significantly (P < 0.01) more severe lesions when compared with other isolates. There were strong correlations between the clinical signs and the severity of lesions.
    Matched MeSH terms: Goat Diseases/microbiology; Goat Diseases/pathology*; Goat Diseases/physiopathology
  7. The first molecular survey of theileriosis in Malaysian cattle, sheep and goats
    Kho KL, Amarajothi ADG, Koh FX, Panchadcharam C, Hassan Nizam QN, Tay ST
    Vet Parasitol Reg Stud Reports, 2017 12;10:149-153.
    PMID: 31014589 DOI: 10.1016/j.vprsr.2017.08.003
    This study reports the molecular detection of Theileria spp. from six cattle farms, a sheep farm and a goat farm located at different states in Peninsular Malaysia. Animal blood samples were screened for the presence of Theileria DNA using a conventional polymerase chain reaction (PCR) assay. A total of 155 (69.2%) of 224 cattle investigated were PCR-positive for Theileria DNA. The occurrences of Theileria spp. ranged from 17.5% to 100.0% across six cattle farms. Theileria DNA was detected from 90.0% of 40 sheep but none of 40 goats examined in this study. Sequence analyses of amplified 18S rRNA partial fragments (335-338bp) confirmed the identification of Theileria buffeli, Theileria sergenti, and Theileria sinensis in representative samples of cattle and ticks. T. luwenshuni was identified in the infected sheep. The high occurrences of Theileria spp. in our farm animals highlight the needs for appropriate control and preventive measures for theileriosis.
    Matched MeSH terms: Goat Diseases/blood; Goat Diseases/epidemiology; Goat Diseases/parasitology*
  8. Responses of testosterone hormone concentration, semen quality, and its related pro-inflammatory cytokines in bucks following Corynebacterium pseudotuberculosis and its mycolic acid infection
    Faeza NMN, Jesse FFA, Hambali IU, Odhah MN, Umer M, Wessam MMS, et al.
    Trop Anim Health Prod, 2019 Sep;51(7):1855-1866.
    PMID: 30945156 DOI: 10.1007/s11250-019-01878-2
    Corynebacterium pseudotuberculosis is the causative agent of caseous lymphadenitis, a debilitating chronic disease of sheep and goats. Little is known about the buck's reproductive pathophysiology with respect to inoculation with Corynebacterium pseudotuberculois and its immunogen mycolic acid extract. Therefore, this present study was designed to determine the concentration of testosterone hormone, pro-inflammatory cytokines, and semen quality of the experimental animals. A total of 12 bucks, divided into groups 1, 2, and 3 (Negative control group, Positive control group and Mycolic acid group respectively), were enrolled in this study. Following inoculation, all goats were observed for clinical responses and monitored for 60 days post-challenge and were then sacrificed. Blood samples were collected via the jugular once before inoculation and on a weekly basis post-challenge. Semen samples were collected 2 weeks post-challenge and prior to the sacrifice of the experimental animals. During the post inoculation period of 60 days, the concentration of testosterone hormone for group 2 was increased significantly (p  0.05) but increased significantly (p  0.05) as compared to group 1. The concentration of interferon-γ (IFNγ) significantly increased (p  0.05) compared to group 1. Both group 2 and group 3 showed a reduction in semen qualities as compared to group 1, but the severity was more intense in group 2 if compared to group 3. In conclusion, therefore, the present study concluded that the mycolic acid group revealed significant responses of testosterone hormone concentration, semen quality, and its related pro-inflammatory cytokines in bucks following infection but the severity lesser compared to Corynebacterium pseudotuberculosis group.
    Matched MeSH terms: Goat Diseases/immunology; Goat Diseases/microbiology; Goat Diseases/physiopathology
  9. The prevalence and distribution of Brucella melitensis in goats in Malaysia from 2000 to 2009
    Bamaiyi PH, Hassan L, Khairani-Bejo S, ZainalAbidin M, Ramlan M, Adzhar A, et al.
    Prev Vet Med, 2015 May 1;119(3-4):232-6.
    PMID: 25746928 DOI: 10.1016/j.prevetmed.2015.02.001
    A study was conducted to describe the prevalence and distribution of zoonotic Brucella melitensis in goats in Peninsular Malaysia. Using serosurveillance data of the last decade (2000-2009) involving 119,799 goats and 3555 farms, the seroprevalence of brucellosis among goats was 0.91% (95% CI=0.86-0.96) and among farms was 7.09% (95% CI=6.27-7.98). The odds of brucellosis was significantly (P<0.05) higher in the later part of the decade, in larger herd size and among the states located in the peninsula as compared to eastern Malaysia. The infection was detected throughout Malaysia but at generally low seroprevalences with states like Perlis that border neighbouring countries having higher seroprevalence of brucellosis than other non-border states.
    Matched MeSH terms: Goat Diseases/microbiology; Goat Diseases/epidemiology*
  10. Case-control study on risk factors associated with Brucella melitensis in goat farms in Peninsular Malaysia
    Bamaiyi PH, Hassan L, Khairani-Bejo S, ZainalAbidin M, Ramlan M, Krishnan N, et al.
    Trop Anim Health Prod, 2014 Jun;46(5):739-45.
    PMID: 24633657 DOI: 10.1007/s11250-014-0557-x
    Caprine brucellosis is a bacterial zoonotic infection affecting goats especially in developing countries all over the world. In Malaysia, the risk factors associated with this infection in farms have not been studied. A case-control study was carried out in goat farms in four states of Malaysia to elucidate the risk factors associated with the infection on the farms using structured questionnaires and face-to-face interviews. Results indicate that the introduction of new animals (OR = 5.25; 90 % CI = 1.46, 18.88), younger age category of farms (OR = 5.53; 90 % CI = 1.09, 21.66), and farms with single breed of goats (OR = 8.50; 90 % CI = 1.27, 41.97) were significant risk factors for brucellosis. In order to control brucellosis or possibly eradicate it in goat farms, these factors need to be dealt with. Enforcing stringent importation protocols or complete ban of goat importation from brucellosis endemic countries will help reduce risk of introducing new infection into the country.
    Matched MeSH terms: Goat Diseases/microbiology*; Goat Diseases/epidemiology
  11. Experimental transmission of Pasteurella multocida 6:B in goats
    Shafarin MS, Zamri-Saad M, Jamil SM, Siti Khairani B, Saharee AA
    J Vet Med A Physiol Pathol Clin Med, 2007 Apr;54(3):136-9.
    PMID: 17381677
    Haemorrhagic septicaemia (HS) is an acute disease of cattle and buffaloes caused by Pasteurella multocida 6:B. Outbreaks of the disease have been closely associated with carrier animals that transmit the organism to susceptible animals during stressful condition. This study was conducted to determine whether goats exposed intranasally to P. multocida 6:B can transmit the organism to contact goats. Thirty-six healthy local Katjang goats were divided into four groups and goats of groups 1 and 3 were each inoculated intranasally with a 1-ml inoculum that contained 1 x 10(9) CFU/ml of live P. multocida 6:B. Following the exposure, all goats of groups 3 and 4 were injected with dexamethasone at the rate of 1 mg/kg for three consecutive days. At the end of the dexamethasone treatment, goats of groups 1 and 2 were commingled but kept separate from goats of groups 3 and 4, which were commingled in another pen. Three surviving goats from each group were killed on days 7, 14 and 21 post-exposure for postmortem examination. Naso-pharyngeal mucus and heart blood were collected on swabs. Tissues from lungs, lymph nodes and tonsils were collected for bacteriological isolation and identification. Only one goat of group 3 died 6 days post-exposure showing clinical signs and lesions typical of HS. Other goats showed mild signs of upper respiratory tract infection. Goats of all groups developed acute mild pneumonic lesions, however, those treated with dexamethasone had significantly (P < 0.05) more extensive lesion scoring based on the lesion scoring system. P. multocida 6:B was isolated from the nasal mucosa and lung lesions of exposed and contact goats not treated with dexamethasone. Exposed and contact goats treated with dexamethasone carried the organism for 21 days. P. multocida isolation from heart blood was made only from exposed and contact goats treated with dexamethasone. P. multocida was isolated from the lymph node of the goat that died during the experiment.
    Matched MeSH terms: Goat Diseases/pathology; Goat Diseases/transmission*
  12. Severe complications induced by experimental bacterial superinfection of orf lesions
    Zamri-Saad M, Roshidah I, al-Ajeeli KS, Ismail MS, Kamarzaman A
    Trop Anim Health Prod, 1993 May;25(2):85-8.
    PMID: 8236484
    Twelve goats about 3 months of age were divided into 4 equal groups. Goats in Groups 1 and 2 were infected with orf virus followed by Corynebacterium pyogenes infection of Groups 1 and 3, 3 days after the first appearance of orf lesions. Goats in Group 4 were uninfected controls. Complicated orf lesions which consisted of wet suppurative scabs around the entire lips were observed in goats in Group 1. The lesions persisted for 24 days but were most severe from days 8 to 13. Goats in Group 2 developed lesions typical of orf virus infection that lasted 10 days, while goats in Group 3 developed small nodules of about 1 cm diameter, 48 hours following the introduction of C. pyogenes, which persisted for only 6 days. No lesion was observed in goats in Group 4. Two goats in Group 1 with complicated orf died after 16 and 22 days respectively.
    Matched MeSH terms: Goat Diseases/microbiology*; Goat Diseases/pathology
  13. A severe outbreak of orf involving the buccal cavity of goats
    Zamri-Saad M, al-Ajeeli KS, Ibrahim AL
    Trop Anim Health Prod, 1992 Aug;24(3):177-8.
    PMID: 1304665
    Matched MeSH terms: Goat Diseases/mortality; Goat Diseases/epidemiology*
  14. Survey on the importance of mange in the aetiology of skin lesions in goats in Peninsular Malaysia
    Dorny P, Van Wyngaarden T, Vercruysse J, Symoens C, Jalia A
    Trop Anim Health Prod, 1994 May;26(2):81-6.
    PMID: 7941034
    A survey on mange mite infestations in the aetiology of skin lesions in goats in Peninsular Malaysia is described. Skin lesions were observed in 25 (93%) of the 27 goat farms investigated. Mange mites were found in 22 (88%) of these goat herds. Chorioptes texanus was found in 20.7%, Psoroptes cuniculi in 19.3%, Sarcoptes scabiei in 18.6% and Demodex canis var. caprae in 0.4% of the samples, taken from the skin lesions. Thirteen cases of generalised manage were diagnosed, from which 9 were caused by S. scabiei, 2 by P. cuniculi and one by C. texanus. All other cases had more or less localised lesions. No significant differences could be found in incidence and distribution of skin lesions between age classes.
    Matched MeSH terms: Goat Diseases/epidemiology; Goat Diseases/parasitology*
  15. Changes in liveweight gain, blood constituents and worm egg output in goats infected with a sheep-derived strain of Trichostrongylus colubriformis
    Rahman WA, Collins GH
    Br. Vet. J., 1990 Sep-Oct;146(5):413-8.
    PMID: 2224486
    Two groups of goats were dosed with 20,000 and 40,000 sheep-derived strain (SDS) larvae of Trichostrongylus colubriformis respectively. Over a period of 42 days, goats dosed with 40,000 larvae lost more weight than goats dosed with 20,000 larvae. Anaemia was not observed in infected goats, but total serum proteins, albumins and phosphorus fell with infection.
    Matched MeSH terms: Goat Diseases/blood; Goat Diseases/physiopathology*
  16. Changes in liveweight gain and blood constituents in experimental infection of goats with a goat-derived compared with a sheep-derived strain of Haemonchus contortus
    Rahman WA, Collins GH
    Vet Parasitol, 1991 Mar;38(2-3):145-53.
    PMID: 1858284
    Two groups of goats were experimentally infected with two different strains of Haemonchus contortus and compared with the controls. Group A animals were infected with a goat-derived strain (GDS) while Group B animals were infected with a sheep-derived strain (SDS). Changes in the liveweights and some blood constitutents between the two infected groups were compared. The pathogenic effects of the GDS larvae were generally more serious when compared with those of the SDS larvae.
    Matched MeSH terms: Goat Diseases/mortality; Goat Diseases/parasitology*
  17. Changes in liveweight gain, blood constituents and worm egg output in goats artificially infected with a sheep-derived strain of Haemonchus contortus
    Rahman WA, Collins GH
    Br. Vet. J., 1990 Nov-Dec;146(6):543-50.
    PMID: 2271911
    Two groups of goats were dosed with 10,000 and 20,000 sheep-derived strain (SDS) larvae of Haemonchus contortus respectively. Over a period of 42 days goats dosed with 20,000 larvae lost more weight than those dosed with 10,000 larvae. Infected goats showed anaemia from about 2 weeks after infection as well as reduced levels of total serum proteins and albumins.
    Matched MeSH terms: Goat Diseases/blood*; Goat Diseases/metabolism
  18. Effect of ivermectin on sarcoptic mange lesions of goats
    Zamri-Saad M, Kamal Hizat A, Kamil WM
    Trop Anim Health Prod, 1990 May;22(2):144-5.
    PMID: 2371754
    Matched MeSH terms: Goat Diseases/drug therapy*; Goat Diseases/pathology
  19. Boer goats appear to lack a functional IgA and eosinophil response against natural nematode infection
    Basripuzi NH, Salisi MS, Isa NMM, Busin V, Cairns C, Jenvey C, et al.
    Vet Parasitol, 2018 Dec 15;264:18-25.
    PMID: 30503086 DOI: 10.1016/j.vetpar.2018.10.014
    Gastrointestinal nematode infection is one of the major diseases affecting small ruminants. Although some breeds of goats are quite resistant, many breeds of goats are relatively susceptible. This study used a combined parasitological, immunological, bioinformatic and statistical approach to examine the role of goat IgA and eosinophils in protection against Teladorsagia circumcincta. Molecular modelling suggested that the transmembrane domain of the high affinity IgA receptor was dysfunctional in goats. Statistical analyses failed to find any association in naturally infected goats between high IgA or eosinophil responses and low faecal egg counts. Together these results indicate that IgA and eosinophil responses against T. circumcincta are less effective in goats than sheep.
    Matched MeSH terms: Goat Diseases/immunology*; Goat Diseases/parasitology
  20. Fulltext An association of Orf virus infection among sheep and goats with herd health programme in Terengganu state, eastern region of the peninsular Malaysia
    Bala JA, Balakrishnan KN, Abdullah AA, Adamu L, Noorzahari MSB, May LK, et al.
    BMC Vet Res, 2019 Jul 18;15(1):250.
    PMID: 31319873 DOI: 10.1186/s12917-019-1999-1
    BACKGROUND: Orf virus causes a scabby skin lesions which decreases productivity in small ruminants. The unknown status of this disease in the eastern region of Peninsular Malaysia warrants a study to determine sero-prevalence of orf with regards to farmers' compliance level towards the Herd Health Program (HHP) programme.

    RESULTS: Out of 504 animals, 115 were positive for Orf-virus antibodies. An overall prevalence rate of 22.8% indicated a high prevalence of orf disease in this region. It was observed that 25.1% (92/367) of goats were positive and 16.8% (23/137) of sheep sero-converted for Orf virus antibody. Several factors were measured for their possible association with prevalence of Orf virus infection. The prevalence was higher in LY farm, JC breed, kid and female animals, and in the presence of disease lesion. Chi-square analysis showed a significant association of three risk factors which are species, age and sex of the animals (P  0.05). Farms surveyed usually practised intensive management system, keeping animals in the shade at all time, due to limited availability of suitable land as a free-range grazing area. An interview with small holder farmers revealed a lack of awareness of the main goals of herd health programme. An overall compliance level of 42.7% was observed for all HHP parameters. Among the 14 main components of HHP modules, animal identification had recorded highest compliance level (84.62%) while milking management recorded the least compliance (- 82.69%). That explained why there was a high sporadic prevalence of Orf infection in this region.

    CONCLUSION: Good herd health supervision is a rehearsal target to prevent an outbreak and the spread of diseases thus reduces economic losses among farmers. Therefore, a good herd health programme should be in place, in order to prevent and control disease transmission as well as to improve herd immunity.

    Matched MeSH terms: Goat Diseases/epidemiology*; Goat Diseases/virology
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