Displaying all 3 publications

Abstract:
Sort:
  1. N2 as a root filling material--a report of 200 cases treated over a 5 yeer period
    Chong LE, Jow TK
    Dent J Malaysia Singapore, 1967 Oct;7(2):44-51.
    PMID: 5247441
    Matched MeSH terms: Formaldehyde/therapeutic use
  2. Fulltext Formalin dab for radiation proctitis--an effective day care procedure
    Ramesh G, Khamizar W
    Med J Malaysia, 2005 Jun;60(2):201-3.
    PMID: 16114161
    The use of high voltage radiotheraphy in pelvi malignancies has led to a common complication which is radiation . proctitis. Treatment with rectal formalin is simple and effective and can be done as a day care procedure. The use of formalin dab was assessed as a day care procedure in our surgical unit in which ten patients were prospectively evaluated. Outcome of these patients was encouraging.
    Matched MeSH terms: Formaldehyde/therapeutic use*
  3. Fulltext A Randomized Controlled Trial of Novel Treatment for Hemorrhagic Radiation Proctitis
    Pui WC, Chieng TH, Siow SL, Nik Abdullah NA, Sagap I
    Asian Pac J Cancer Prev, 2020 Oct 01;21(10):2927-2934.
    PMID: 33112550 DOI: 10.31557/APJCP.2020.21.10.2927
    BACKGROUND: Various methods have been used for treatment of hemorrhagic radiation proctitis (HRP) with variable results. Currently, the preferred treatment is formalin application or endoscopic therapy with argon plasma coagulation. Recently, a novel therapy with colonic water irrigation and oral antibiotics showed promising results and more effective compared to 4% formalin application for HRP. The study objective is to compare the effect of water irrigation and oral antibiotics versus 4% formalin application in improving per rectal bleeding due to HRP and related symptoms such as diarrhoea, tenesmus, stool frequency, stool urgency and endoscopic findings.

    METHODS: We conducted a study on 34 patients with HRP and randomly assigned the patients to two treatment arm groups (n=17). The formalin group underwent 4% formalin dab and another session 4 weeks later. The irrigation group self-administered daily rectal irrigation at home for 8 weeks and consumed oral metronidazole and ciprofloxacin during the first one week. We measured the patients' symptoms and endoscopic findings before and after total of 8 weeks of treatment in both groups.

    RESULTS: Our study showed that HRP patients had reduced per rectal bleeding (p = 0.003) in formalin group, whereas irrigation group showed reduced diarrhoea (p=0.018) and tenesmus (p=0.024) symptoms. The comparison between the two treatment arms showed that irrigation technique was better than formalin technique for tenesmus (p=0.043) symptom only.

    CONCLUSION: This novel treatment showed benefit in treating HRP. It could be a new treatment option which is safe and conveniently self-administered at home or used as a combination with other therapies to improve the treatment outcome for HRP.
    .

    Matched MeSH terms: Formaldehyde/therapeutic use*
Related Terms
    Try searching for something
Filters
Contact Us

Please provide feedback to Administrator ([email protected])

External Links