Displaying publications 1 - 20 of 36 in total

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  1. Lesions of the extremities in diabetes mellitus
    Abdul Hamid AK
    Family Physician, 1989;1:56-59.
    Matched MeSH terms: Extremities
  2. Localised gigantism of the extremities
    Khaw JH, Datuk Omar bin Din
    Med J Malaysia, 1973 Jun;27(4):292-8.
    PMID: 4270789
    Matched MeSH terms: Extremities*
  3. Subcutaneous versus intravenous tramadol for extremity injury with moderate pain in the emergency department: a randomised controlled noninferiority trial
    Bustam A, Poh K, Zambri A, Mohd Nazri MZA, Subramaniam T, Abdullah AA, et al.
    Eur J Emerg Med, 2023 Oct 01;30(5):331-340.
    PMID: 37276052 DOI: 10.1097/MEJ.0000000000001047
    BACKGROUND AND IMPORTANCE: Musculoskeletal trauma is a common presentation in the emergency department (ED). Tramadol as an analgesic has been recommended by pain management guidelines for musculoskeletal pain. Parenteral tramadol in the ED is commonly administered intravenously. Subcutaneously administered tramadol may have other advantages such as easier and faster preparation, avoids the need for intravenous (i.v.) access, and reduces the incidence of respiratory and gastrointestinal effects. However, studies comparing subcutaneous (s.c.) and i.v. tramadol for the management of acute moderate pain in patients with extremity injury are lacking.

    OBJECTIVE: The objective of this study was to compare the clinical efficacy of s.c. tramadol vs. i.v. tramadol in patients with moderate pain due to extremity injury in the ED.

    DESIGN, SETTINGS, AND PARTICIPANTS: This non-inferiority randomized controlled trial included adult patients presented to an academic, tertiary hospital ED with moderate pain (pain score of 4-6 on the visual analog scale) due to extremity injury. Intervention patients stratified to pain score were randomized to receive 50 mg of i.v. or s.c. tramadol.

    OUTCOMES MEASURE AND ANALYSIS: Primary outcome measure was the difference in the pain score reduction at 30 min after tramadol administration between the two groups. The noninferiority null hypothesis was that the therapeutic difference in terms of pain score reduction of more than 0.8 exists between the two treatment groups at the endpoint.

    MAIN RESULTS: In total 232 patients were randomized to i.v. ( n  = 115) or s.c. ( n  = 117). Although 225 were analyzed in the per-protocol population (i.v. = 113; s.c. = 112). The baseline median pain score was 6 (IQR, 5-6). Median pain score reduction at 30 min after administration was 2 (IQR, 1-3) in the IV group vs. 2 (IQR, 1-2) in the s.c. group with a median difference of 0 (IQR, 0-0), which was below the prespecified noninferiority margin of 0.8. Adverse events in the i.v. group were higher compared to the s.c. group (33.6% vs. 8.9%, P  ≤ 0.001).

    CONCLUSIONS: The s.c. tramadol is noninferior to i.v. tramadol in the treatment of moderate pain from extremity injuries.

    Matched MeSH terms: Extremities/injuries
  4. Fulltext Aristolochia vallisicola (Aristolochiaceae), a new species from Peninsular Malaysia
    Yao TL
    PhytoKeys, 2012.
    PMID: 23170070 DOI: 10.3897/phytokeys.14.3354
    A new species in the genus Aristolochia (Aristolochiaceae), Aristolochia vallisicola T.L.Yao, from Peninsular Malaysia is described and illustrated. Among all Peninsular Malaysian Aristolochia,itis the only species with a pinnately veined lamina and a disc-liked perianth limb. A distribution map is provided and its conservation status is assessed as Least Concern.
    Matched MeSH terms: Extremities
  5. A male black fly of Simulium (Simulium) iwatense (Shiraki) (Diptera: Simuliidae) with genitalia-like appendages on abdominal segment 8
    Takaoka H, Fukuda M, Otsuka Y, Iwasa M
    Trop Biomed, 2021 Jun 01;38(2):68-71.
    PMID: 33973575 DOI: 10.47665/tb.38.2.040
    A rare non-sex mosaic abnormality represented by genitalia-like appendages on the ventral surface of abdominal segment 8 of a male black fly collected in Hokkaido, Japan, is reported. The appendages consist of a pair of style-like projections each arising from a coxite-like base, inverted-Y shaped ventral plate-like structure, and isolated round structure. This male was morphologically and molecularly identified as an abnormal form of S. (S.) iwatense (Shiraki), the only species in the Simulium (Simulium) ornatum species-group in Japan, although certain morphological characteristics of this male including the reduced number of uppereye (large) facets and elongate cerci are different from those of S. (S.) iwatense.
    Matched MeSH terms: Extremities
  6. Fulltext Immediate Revascularization of A Traumatic Limb Vascular Injury associated with Major Pelvic Injuries
    Hanifah J, Paiman M, Nawfar AS, Tengku-Muzaffar T, Wan-Azman WS, Faisham WI, et al.
    Malays Orthop J, 2015 Nov;9(3):61-64.
    PMID: 28611914 MyJurnal DOI: 10.5704/MOJ.1511.014
    High velocity pelvic injury with limb vascular injury poses difficulties as immediate surgery for limb reperfusion is indicated. However immediate vascular intervention deviates from conventional principles of damage control following major injuries. We present two cases of this rare combination of injuries. In both cases, early limb revascularization is possible despite presented with multiple injuries and pelvic fracture.
    Matched MeSH terms: Extremities
  7. Fulltext Thismiadomei and T.terengganuensis (Thismiaceae), two new species, and T.javanica, a new record from Terengganu, Peninsular Malaysia
    Yunoh SM, Nikong D
    PhytoKeys, 2019;124:123-137.
    PMID: 31274980 DOI: 10.3897/phytokeys.124.34728
    Two new species of the mycoheterotrophic genus Thismia Griff. (Thismiaceae), Thismiadomei Siti-Munirah and T.terengganuensis Siti-Munirah from Peninsular Malaysia, are described and illustrated. Thismiadomei, characterized by its perianth lobes that are upright and curve inward, but are imperfectly connate, falls within sectionOdoardoa. Thismiaterengganuensis is characterized by its mitre with three appendages on its apex, so falls within sectionGeomitra. Both new species are unique and totally different from other described species, T.domei by the trichomes on its outer perianth tube surface and T.terengganuensis by its mitre with slender appendages. Thismiajavanica J.J.Sm, also from Terengganu, is a new record for Peninsular Malaysia.
    Matched MeSH terms: Extremities
  8. Intestinal polyposis with pigmentation of oral mucosa and digits (Peutz-Jeghers syndrome); report of a case in a Chinese
    YUNIBANDHU J
    Med J Malaya, 1957 Dec;12(2):440-7.
    PMID: 13515876
    Matched MeSH terms: Extremities*
  9. Fulltext Repair of segmental load-bearing bone defect by autologous mesenchymal stem cells and plasma-derived fibrin impregnated ceramic block results in early recovery of limb function
    Ng MH, Duski S, Tan KK, Yusof MR, Low KC, Rose IM, et al.
    Biomed Res Int, 2014;2014:345910.
    PMID: 25165699 DOI: 10.1155/2014/345910
    Calcium phosphate-based bone substitutes have not been used to repair load-bearing bone defects due to their weak mechanical property. In this study, we reevaluated the functional outcomes of combining ceramic block with osteogenic-induced mesenchymal stem cells and platelet-rich plasma (TEB) to repair critical-sized segmental tibial defect. Comparisons were made with fresh marrow-impregnated ceramic block (MIC) and partially demineralized allogeneic bone block (ALLO). Six New Zealand White female rabbits were used in each study group and three rabbits with no implants were used as negative controls. By Day 90, 4/6 rabbits in TEB group and 2/6 in ALLO and MIC groups resumed normal gait pattern. Union was achieved significantly faster in TEB group with a radiological score of 4.50 ± 0.78 versus ALLO (1.06 ± 0.32), MIC (1.28 ± 0.24), and negative controls (0). Histologically, TEB group scored the highest percentage of new bone (82% ± 5.1%) compared to ALLO (5% ± 2.5%) and MIC (26% ± 5.2%). Biomechanically, TEB-treated tibiae achieved the highest compressive strength (43.50 ± 12.72 MPa) compared to those treated with ALLO (15.15 ± 3.57 MPa) and MIC (23.28 ± 6.14 MPa). In conclusion, TEB can repair critical-sized segmental load-bearing bone defects and restore limb function.
    Matched MeSH terms: Extremities/growth & development; Extremities/injuries; Extremities/physiopathology
  10. Fulltext Complete Brachial Plexus Injury - An Amputation Dilemma. A Case Report
    Choong C, Shalimar A, Jamari S
    Malays Orthop J, 2015 Nov;9(3):52-54.
    PMID: 28611911 MyJurnal DOI: 10.5704/MOJ.1511.017
    Brachial plexus injuries with intact yet flail limb presents with problems of persistent neuropathic pain and recurrent shoulder dislocations, that render the flail limb a damn nuisance. As treating surgeons, we are faced with the dilemma of offering treatment options, bearing in mind the patient's functional status and expectations. We present a case of a 55-year old housewife with complete brachial plexus injury begging for surgical amputation of her flail limb, 6 years post-injury. Here we discuss the outcome of transhumeral amputation and the possibility of offering early rather than delayed amputations in this group of patients.
    Matched MeSH terms: Extremities
  11. Fulltext Pengambilan sarapan pagi dan pengaruh ke atas pencapaian kognitif kanak-kanak sekolah rendah
    Shazli Ezzat Ghazali, Noor Aini Mohd Yusoff, Ponnusamy, S., Syahiza Abas
    Jurnal Sains Kesihatan Malaysia, 2005;3(1):1-7.
    MyJurnal
    Perkembangan kognitif dan pertumbuhan fizikal di kalangan kanak-kanak bergantung kepada status pemakanan mereka, termasuklah tabiat pengambilan sarapan pagi. Objektif kajian ini adalah untuk melihat pengaruh pengambilan sarapan pagi sebelum ke sekolah ke atas pencapaian kognitif kanak-kanak sekolah rendah. Satu kajian hirisan lintang dijalankan di kalangan kanak-kanak sekolah rendah di bandar dan luar bandar. Subjek kajian mengandungi 165 pelajar Melayu yang berusia 10 tahun. Tiga jenis subskala daripada ujian Wechsler Wechsler Intelligence Scale For Children-III digunakan untuk mengukur tahap kognitif kanak-kanak tersebut iaitu arithmatik, pengkodan dan digit span. Hasil kajian didapati kanak-kanak yang mengambil sarapan pagi mencatatkan pencapaian yang tinggi secara signifikan dalam arithmetik (p
    Matched MeSH terms: Extremities
  12. Fulltext Synovial Sarcoma of the Extremities. A Diagnosis that is Easily Missed.
    Pan, K.L., Prem, S.S., Chan, W.H., Haniza S.
    Malays Orthop J, 2009;3(2):12-15.
    MyJurnal
    Synovial sarcoma of the extremities is an uncommon type of soft tissue sarcoma occuring predominantly in young adults at the para-articular regions. We present a series of 10 patients with an average age of 44 years and include a follow-up of 39 months. Eight patients had a surgical procedure for a mistaken benign lesion. In contrast to other soft tissue sarcomas, the swellings were associated with pain and most were fixed to the underlying structures. Five patients had a local reccurence after many years, stressing the necessity for close and long-term follow-up in these patients.
    Matched MeSH terms: Extremities
  13. Fulltext Management of extensive surgical wounds of the extremity after tumour resections using two simultaneous composite flaps: two case reports
    Faisal, A., Ahmad, S.H., Zulmi, W.
    Journal of Surgical Academia, 2011;1(1):42-45.
    MyJurnal
    Tumour surgery for locally extensive malignant neoplasms of the extremity will sometimes result in extensive composite soft tissue defect. Local flaps are usually inadequate to cover these large defects. More than one tissue flap might be required to cover any exposed neurovascular structures, bone or prosthesis. We present two cases where two composite flaps were simultaneously used to cover extensive surgical defects after ablative tumour resections in the extremity. These resulted in uncomplicated wound healing and limb salvage.
    Matched MeSH terms: Extremities
  14. Simulation and statistical approaches on electrical steel's magnetic behaviour under unidirectional single sheet tester
    Noor Ashikin Mohd Rashid, Wan Nor Liza Wan Mahadi
    Sains Malaysiana, 2014;43:909-914.
    Evaluation of magnetic properties of electrical steel is vital in improving the quality of electrical machinery since it is used as magnetic cores for transformers, motors and generators. A double yoke single sheet tester (ssT) was modeled using two identical C-cores wound with copper wires at limb side in horizontal arrangement. The magnetic properties for electrical steels, grade M4 and M19 were tested under a frequency of 50 Hz with the current ranging from 02 to 2.4A. The effects of the sample dimension and anisotropy on magnetic measurements were investigated. Evaluation on specimen dimensions indicate that the non-uniformity of sample magnetization in overhang sample can attribute to the flux leakage between the yoke legs. The stray flux is also increased with the overhang sample. However, the so-called fit-in sample which is fitted nicely between the yoke end poles can minimize the effect of stray flux. One way ANOVA and T-test were used as statistical methods and executed at the 5% significance level. It is statistically proven that the magnetic properties of both magnetic materials are influenced by their anisotropy.
    Matched MeSH terms: Extremities
  15. Fulltext Newborn with Gastroschisis associated with Limb Anomalies
    Win PP
    J Neonatal Surg, 2017 01 01;6(1):8.
    PMID: 28083494 DOI: 10.21699/jns.v6i1.443
    Gastroschisis is often found together with other extra intestinal conditions such as limb, spine, cardiac, central nervous system and genitourinary abnormalities. There are reports of its association with young maternal age. The cases presented here highlight the association of gastroschisis with limbs anomalies and young maternal age.
    Matched MeSH terms: Extremities
  16. Jumping in lantern bugs (Hemiptera, Fulgoridae)
    Burrows M, Ghosh A, Sutton GP, Yeshwanth HM, Rogers SM, Sane SP
    J Exp Biol, 2021 12 01;224(23).
    PMID: 34755862 DOI: 10.1242/jeb.243361
    Lantern bugs are amongst the largest of the jumping hemipteran bugs, with body lengths reaching 44 mm and masses reaching 0.7 g. They are up to 600 times heavier than smaller hemipterans that jump powerfully using catapult mechanisms to store energy. Does a similar mechanism also propel jumping in these much larger insects? The jumping performance of two species of lantern bugs (Hemiptera, Auchenorrhyncha, family Fulgoridae) from India and Malaysia was therefore analysed from high-speed videos. The kinematics showed that jumps were propelled by rapid and synchronous movements of both hind legs, with their trochantera moving first. The hind legs were 20-40% longer than the front legs, which was attributable to longer tibiae. It took 5-6 ms to accelerate to take-off velocities reaching 4.65 m s-1 in the best jumps by female Kalidasa lanata. During these jumps, adults experienced an acceleration of 77 g, required an energy expenditure of 4800 μJ and a power output of 900 mW, and exerted a force of 400 mN. The required power output of the thoracic jumping muscles was 21,000 W kg-1, 40 times greater than the maximum active contractile limit of muscle. Such a jumping performance therefore required a power amplification mechanism with energy storage in advance of the movement, as in their smaller relatives. These large lantern bugs are near isometrically scaled-up versions of their smaller relatives, still achieve comparable, if not higher, take-off velocities, and outperform other large jumping insects such as grasshoppers.
    Matched MeSH terms: Extremities
  17. Fulltext Heterochely and handedness in the orange mud crab Scylla olivacea: implication for future culture practice optimisation
    Rozaimi R, Shu-Chien AC, Wang Y, Sutikno S, Ikhwanuddin M, Shi X, et al.
    PeerJ, 2023;11:e15143.
    PMID: 37033733 DOI: 10.7717/peerj.15143
    Asymmetric body traits in bilateral organisms are common and serve a range of different functions. In crustaceans, specifically among brachyuran crabs, heterochely and handedness in some species are known to aid in behavioural responses such as food acquisition, and sexual and territorial displays. However, the heterochely of the intertidal mud crab genus Scylla is still poorly understood. This study investigated the cheliped morphometric characteristics of orange mud crab Scylla olivacea and the relation of heterochely and handedness to sex. Scylla olivacea is heterochelous, with predominant right-handed (70.2%). Three morphometric variables, i.e., propodus length (PL), propodus depth (PD), and propodus width (PW) were significantly larger in the right cheliped and the estimated handedness based on these three variables were consistent with the presence of molariform teeth. The effect of sex had no influence on the occurrence of heterochely or handedness. The frequency of left-handedness increased with size, especially in males. We postulate that handedness reversal, a phenomenon seen in other crab species when the dominant hand is lost, also occurs in S. olivacea, thereby resulting in a change in left-handedness frequency. The use of chelipeds by males in mate and territorial defenses might provide an explanation for the higher risk of losing a dominant cheliped and thus, higher left-handedness frequency compared to females. Future behavioural research could shed light on the selective forces that affect the handedness distribution in mud crabs. Knowledge on heterochely and handedness of mud crabs could be useful for future development of less aggressive crab populations by claw reversal and the optimisation of limb autotomy techniques.
    Matched MeSH terms: Extremities
  18. Cell therapy in critical limb ischemia: current developments and future progress
    Mamidi MK, Pal R, Dey S, Bin Abdullah BJ, Zakaria Z, Rao MS, et al.
    Cytotherapy, 2012 Sep;14(8):902-16.
    PMID: 22731756 DOI: 10.3109/14653249.2012.693156
    Critical limb ischemia (CLI) is a syndrome manifested by ischemic rest pain, non-healing ulcers and tissue loss. CLI patients are at very high risk of amputation and experience poor physical function, leading to severe morbidity and mortality. The fundamental goal for CLI treatment is to relieve ischemic rest pain, heal ulcers, prevent limb loss and improve the quality of life, thereby extending the survival of the patient. Surgical or endovascular revascularization aimed at increasing blood flow is currently available for limb salvage in CLI. However, up to 30% of CLI patients are not suitable for such interventions because of high operative risk or unfavorable vascular anatomy. Therefore exploring new and more effective strategies for revascularization of ischemic limbs is imperative for the establishment of a viable therapeutic alternative. With the emergence of new approaches, this review describes up-to-date progress and developments in cell-based therapy as a novel and promising alternative for CLI treatment. Preliminary clinical data have established the safety, feasibility and efficacy of stem cells, and numerous studies are underway to consolidate this evidence further. However, significant hurdles remain to be addressed before this research can be responsibly translated to the bedside. In particular, we need better understanding of the behavior of cells post-transplantation and to learn how to control their survival and migration proliferation/differentiation in the hostile pathologic environment. Future research should focus on methods of isolation, optimal dosage, appropriate cell type, route of administration, role of tissue-derived factors and supportive endogenous stimulation.
    Matched MeSH terms: Extremities/blood supply; Extremities/physiopathology*
  19. Fulltext Limb reconstruction surgery with external fixators--university hospital experience
    Aik S, Sengupta S
    Med J Malaysia, 2000 Sep;55 Suppl C:86-92.
    PMID: 11200049
    We are describing 21 limb reconstruction procedures performed in 18 patients with the use of external fixators from 1996 to 1998. The average age of patients was 21, ranging from 1 to 50 years old. Indications for surgery included short limb, non-union, pseudoarthrosis and bone or soft tissue deformities. Average length obtained for cases of limb lengthening was 6 cm. All the seven clubfoot deformities in five children were fully corrected. Equinus deformity recurred in one foot and was treated with supramalleolar osteotomy. Out of the seven cases with infected nonunion and bone loss, three failed to achieve union and required additional bone grafting procedures. One patient with unilateral external fixator for the correction of tibia shortening developed valgus deformity.
    Matched MeSH terms: Extremities/radiography; Extremities/surgery*
  20. Biomechanics of ant adhesive pads: frictional forces are rate- and temperature-dependent
    Federle W, Baumgartner W, Hölldobler B
    J Exp Biol, 2004 Jan;207(Pt 1):67-74.
    PMID: 14638834
    Tarsal adhesive pads enable insects to hold on to smooth plant surfaces. Using a centrifuge technique, we tested whether a "wet adhesion" model of a thin film of liquid secreted between the pad and the surface can explain adhesive and frictional forces in Asian Weaver ants (Oecophylla smaragdina). When forces are acting parallel to the surface, pads in contact with the surface can slide smoothly. Force per unit pad contact area was strongly dependent on sliding velocity and temperature. Seemingly consistent with the effect of a thin liquid film in the contact zone, (1) frictional force linearly increased with sliding velocity, (2) the increment was greater at lower temperatures and (3) no temperature dependence was detected for low-rate perpendicular detachment forces. However, we observed a strong, temperature-independent static friction that was inconsistent with a fully lubricated contact. Static friction was too large to be explained by the contribution of other (sclerotized) body parts. Moreover, the rate-specific increase of shear stress strongly exceeded predictions derived from estimates of the adhesive liquid film's thickness and viscosity. Both lines of evidence indicate that the adhesive secretion alone is insufficient to explain the observed forces and that direct interaction of the soft pad cuticle with the surface ("rubber friction") is involved.
    Matched MeSH terms: Extremities/anatomy & histology; Extremities/physiology*
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