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A Systematic Review for Human EEG Brain Signals Based Emotion Classification, Feature Extraction, Brain Condition, Group Comparison

Hamada M, Zaidan BB, Zaidan AA

J Med Syst, 2018 Jul 24;42(9):162.
PMID: 30043178 DOI: 10.1007/s10916-018-1020-8

The study of electroencephalography (EEG) signals is not a new topic. However, the analysis of human emotions upon exposure to music considered as important direction. Although distributed in various academic databases, research on this concept is limited. To extend research in this area, the researchers explored and analysed the academic articles published within the mentioned scope. Thus, in this paper a systematic review is carried out to map and draw the research scenery for EEG human emotion into a taxonomy. Systematically searched all articles about the, EEG human emotion based music in three main databases: ScienceDirect, Web of Science and IEEE Xplore from 1999 to 2016. These databases feature academic studies that used EEG to measure brain signals, with a focus on the effects of music on human emotions. The screening and filtering of articles were performed in three iterations. In the first iteration, duplicate articles were excluded. In the second iteration, the articles were filtered according to their titles and abstracts, and articles outside of the scope of our domain were excluded. In the third iteration, the articles were filtered by reading the full text and excluding articles outside of the scope of our domain and which do not meet our criteria. Based on inclusion and exclusion criteria, 100 articles were selected and separated into five classes. The first class includes 39 articles (39%) consists of emotion, wherein various emotions are classified using artificial intelligence (AI). The second class includes 21 articles (21%) is composed of studies that use EEG techniques. This class is named 'brain condition'. The third class includes eight articles (8%) is related to feature extraction, which is a step before emotion classification. That this process makes use of classifiers should be noted. However, these articles are not listed under the first class because these eight articles focus on feature extraction rather than classifier accuracy. The fourth class includes 26 articles (26%) comprises studies that compare between or among two or more groups to identify and discover human emotion-based EEG. The final class includes six articles (6%) represents articles that study music as a stimulus and its impact on brain signals. Then, discussed the five main categories which are action types, age of the participants, and number size of the participants, duration of recording and listening to music and lastly countries or authors' nationality that published these previous studies. it afterward recognizes the main characteristics of this promising area of science in: motivation of using EEG process for measuring human brain signals, open challenges obstructing employment and recommendations to improve the utilization of EEG process.
Challenges, alternatives, and paths to sustainability: better public health promotion using social networking pages as key tools

Zaidan AA, Zaidan BB, Kadhem Z, Larbani M, Lakulu MB, Hashim M

J Med Syst, 2015 Feb;39(2):7.
PMID: 25631841 DOI: 10.1007/s10916-015-0201-y

This paper discusses the possibility of promoting public health and implementing educational health services using Facebook. We discuss the challenges and strengths of using such a platform as a tool for public health care systems from two different perspectives, namely, the view of IT developers and that of physicians. We present a new way of evaluating user interactivity in health care systems from tools provided by Facebook that measure statistical traffic in the Internet. Findings show that Facebook is a very promising tool in promoting e-health services in Web 2.0. Results from statistical traffic show that a Facebook page is more efficient than other pages in promoting public health.
Erratum to: An Enhanced Security Solution for Electronic Medical Records Based on AES Hybrid Technique with SOAP/XML and SHA-1

Kiah ML, Nabi MS, Zaidan BB, Zaidan AA

J Med Syst, 2015 Feb;39(2):2.
PMID: 25600194 DOI: 10.1007/s10916-015-0189-3
Open source EMR software: profiling, insights and hands-on analysis

Kiah ML, Haiqi A, Zaidan BB, Zaidan AA

Comput Methods Programs Biomed, 2014 Nov;117(2):360-82.
PMID: 25070757 DOI: 10.1016/j.cmpb.2014.07.002

The use of open source software in health informatics is increasingly advocated by authors in the literature. Although there is no clear evidence of the superiority of the current open source applications in the healthcare field, the number of available open source applications online is growing and they are gaining greater prominence. This repertoire of open source options is of a great value for any future-planner interested in adopting an electronic medical/health record system, whether selecting an existent application or building a new one. The following questions arise. How do the available open source options compare to each other with respect to functionality, usability and security? Can an implementer of an open source application find sufficient support both as a user and as a developer, and to what extent? Does the available literature provide adequate answers to such questions? This review attempts to shed some light on these aspects.
An enhanced security solution for electronic medical records based on AES hybrid technique with SOAP/XML and SHA-1

Kiah ML, Nabi MS, Zaidan BB, Zaidan AA

J Med Syst, 2013 Oct;37(5):9971.
PMID: 24037086 DOI: 10.1007/s10916-013-9971-2

This study aims to provide security solutions for implementing electronic medical records (EMRs). E-Health organizations could utilize the proposed method and implement recommended solutions in medical/health systems. Majority of the required security features of EMRs were noted. The methods used were tested against each of these security features. In implementing the system, the combination that satisfied all of the security features of EMRs was selected. Secure implementation and management of EMRs facilitate the safeguarding of the confidentiality, integrity, and availability of e-health organization systems. Health practitioners, patients, and visitors can use the information system facilities safely and with confidence anytime and anywhere. After critically reviewing security and data transmission methods, a new hybrid method was proposed to be implemented on EMR systems. This method will enhance the robustness, security, and integration of EMR systems. The hybrid of simple object access protocol/extensible markup language (XML) with advanced encryption standard and secure hash algorithm version 1 has achieved the security requirements of an EMR system with the capability of integrating with other systems through the design of XML messages.
Sensor-Based mHealth Authentication for Real-Time Remote Healthcare Monitoring System: A Multilayer Systematic Review

Shuwandy ML, Zaidan BB, Zaidan AA, Albahri AS

J Med Syst, 2019 Jan 06;43(2):33.
PMID: 30612191 DOI: 10.1007/s10916-018-1149-5

The new and groundbreaking real-time remote healthcare monitoring system on sensor-based mobile health (mHealth) authentication in telemedicine has considerably bounded and dispersed communication components. mHealth, an attractive part in telemedicine architecture, plays an imperative role in patient security and privacy and adapts different sensing technologies through many built-in sensors. This study aims to improve sensor-based defence and attack mechanisms to ensure patient privacy in client side when using mHealth. Thus, a multilayer taxonomy was conducted to attain the goal of this study. Within the first layer, real-time remote monitoring studies based on sensor technology for telemedicine application were reviewed and analysed to examine these technologies and provide researchers with a clear vision of security- and privacy-based sensors in the telemedicine area. An extensive search was conducted to find articles about security and privacy issues, review related applications comprehensively and establish the coherent taxonomy of these articles. ScienceDirect, IEEE Xplore and Web of Science databases were investigated for articles on mHealth in telemedicine-based sensor. A total of 3064 papers were collected from 2007 to 2017. The retrieved articles were filtered according to the security and privacy of sensor-based telemedicine applications. A total of 19 articles were selected and classified into two categories. The first category, 57.89% (n = 11/19), included survey on telemedicine articles and their applications. The second category, 42.1% (n = 8/19), included articles contributed to the three-tiered architecture of telemedicine. The collected studies improved the essential need to add another taxonomy layer and review the sensor-based smartphone authentication studies. This map matching for both taxonomies was developed for this study to investigate sensor field comprehensively and gain access to novel risks and benefits of the mHealth security in telemedicine application. The literature on sensor-based smartphones in the second layer of our taxonomy was analysed and reviewed. A total of 599 papers were collected from 2007 to 2017. In this layer, we obtained a final set of 81 articles classified into three categories. The first category of the articles [86.41% (n = 70/81)], where sensor-based smartphones were examined by utilising orientation sensors for user authentication, was used. The second category [7.40% (n = 6/81)] included attack articles, which were not intensively included in our literature analysis. The third category [8.64% (n = 7/81)] included 'other' articles. Factors were considered to understand fully the various contextual aspects of the field in published studies. The characteristics included the motivation and challenges related to sensor-based authentication of smartphones encountered by researchers and the recommendations to strengthen this critical area of research. Finally, many studies on the sensor-based smartphone in the second layer have focused on enhancing accurate authentication because sensor-based smartphones require sensors that could authentically secure mHealth.
A review of disability EEG based wheelchair control system: Coherent taxonomy, open challenges and recommendations

Al-Qaysi ZT, Zaidan BB, Zaidan AA, Suzani MS

Comput Methods Programs Biomed, 2018 Oct;164:221-237.
PMID: 29958722 DOI: 10.1016/j.cmpb.2018.06.012

CONTEXT: Intelligent wheelchair technology has recently been utilised to address several mobility problems. Techniques based on brain-computer interface (BCI) are currently used to develop electric wheelchairs. Using human brain control in wheelchairs for people with disability has elicited widespread attention due to its flexibility.
OBJECTIVE: This study aims to determine the background of recent studies on wheelchair control based on BCI for disability and map the literature survey into a coherent taxonomy. The study intends to identify the most important aspects in this emerging field as an impetus for using BCI for disability in electric-powered wheelchair (EPW) control, which remains a challenge. The study also attempts to provide recommendations for solving other existing limitations and challenges.
METHODS: We systematically searched all articles about EPW control based on BCI for disability in three popular databases: ScienceDirect, IEEE and Web of Science. These databases contain numerous articles that considerably influenced this field and cover most of the relevant theoretical and technical issues.
RESULTS: We selected 100 articles on the basis of our inclusion and exclusion criteria. A large set of articles (55) discussed on developing real-time wheelchair control systems based on BCI for disability signals. Another set of articles (25) focused on analysing BCI for disability signals for wheelchair control. The third set of articles (14) considered the simulation of wheelchair control based on BCI for disability signals. Four articles designed a framework for wheelchair control based on BCI for disability signals. Finally, one article reviewed concerns regarding wheelchair control based on BCI for disability signals.
DISCUSSION: Since 2007, researchers have pursued the possibility of using BCI for disability in EPW control through different approaches. Regardless of type, articles have focused on addressing limitations that impede the full efficiency of BCI for disability and recommended solutions for these limitations.
CONCLUSIONS: Studies on wheelchair control based on BCI for disability considerably influence society due to the large number of people with disability. Therefore, we aim to provide researchers and developers with a clear understanding of this platform and highlight the challenges and gaps in the current and future studies.
Fulltext Detection-based prioritisation: Framework of multi-laboratory characteristics for asymptomatic COVID-19 carriers based on integrated Entropy-TOPSIS methods

Albahri AS, Hamid RA, Albahri OS, Zaidan AA

Artif Intell Med, 2021 Jan;111:101983.
PMID: 33461683 DOI: 10.1016/j.artmed.2020.101983

CONTEXT AND BACKGROUND: Corona virus (COVID) has rapidly gained a foothold and caused a global pandemic. Particularists try their best to tackle this global crisis. New challenges outlined from various medical perspectives may require a novel design solution. Asymptomatic COVID-19 carriers show different health conditions and no symptoms; hence, a differentiation process is required to avert the risk of chronic virus carriers.
OBJECTIVES: Laboratory criteria and patient dataset are compulsory in constructing a new framework. Prioritisation is a popular topic and a complex issue for patients with COVID-19, especially for asymptomatic carriers due to multi-laboratory criteria, criterion importance and trade-off amongst these criteria. This study presents new integrated decision-making framework that handles the prioritisation of patients with COVID-19 and can detect the health conditions of asymptomatic carriers.
METHODS: The methodology includes four phases. Firstly, eight important laboratory criteria are chosen using two feature selection approaches. Real and simulation datasets from various medical perspectives are integrated to produce a new dataset involving 56 patients with different health conditions and can be used to check asymptomatic cases that can be detected within the prioritisation configuration. The first phase aims to develop a new decision matrix depending on the intersection between 'multi-laboratory criteria' and 'COVID-19 patient list'. In the second phase, entropy is utilised to set the objective weight, and TOPSIS is adapted to prioritise patients in the third phase. Finally, objective validation is performed.
RESULTS: The patients are prioritised based on the selected criteria in descending order of health situation starting from the worst to the best. The proposed framework can discriminate among mild, serious and critical conditions and put patients in a queue while considering asymptomatic carriers. Validation findings revealed that the patients are classified into four equal groups and showed significant differences in their scores, indicating the validity of ranking.
CONCLUSIONS: This study implies and discusses the numerous benefits of the suggested framework in detecting/recognising the health condition of patients prior to discharge, supporting the hospitalisation characteristics, managing patient care and optimising clinical prediction rule.
A security framework for nationwide health information exchange based on telehealth strategy

Zaidan BB, Haiqi A, Zaidan AA, Abdulnabi M, Kiah ML, Muzamel H

J Med Syst, 2015 May;39(5):51.
PMID: 25732083 DOI: 10.1007/s10916-015-0235-1

This study focuses on the situation of health information exchange (HIE) in the context of a nationwide network. It aims to create a security framework that can be implemented to ensure the safe transmission of health information across the boundaries of care providers in Malaysia and other countries. First, a critique of the major elements of nationwide health information networks is presented from the perspective of security, along with such topics as the importance of HIE, issues, and main approaches. Second, a systematic evaluation is conducted on the security solutions that can be utilized in the proposed nationwide network. Finally, a secure framework for health information transmission is proposed within a central cloud-based model, which is compatible with the Malaysian telehealth strategy. The outcome of this analysis indicates that a complete security framework for a global structure of HIE is yet to be defined and implemented. Our proposed framework represents such an endeavor and suggests specific techniques to achieve this goal.
Fulltext Evaluation and selection of open-source EMR software packages based on integrated AHP and TOPSIS

Zaidan AA, Zaidan BB, Al-Haiqi A, Kiah ML, Hussain M, Abdulnabi M

J Biomed Inform, 2015 Feb;53:390-404.
PMID: 25483886 DOI: 10.1016/j.jbi.2014.11.012

Evaluating and selecting software packages that meet the requirements of an organization are difficult aspects of software engineering process. Selecting the wrong open-source EMR software package can be costly and may adversely affect business processes and functioning of the organization. This study aims to evaluate and select open-source EMR software packages based on multi-criteria decision-making. A hands-on study was performed and a set of open-source EMR software packages were implemented locally on separate virtual machines to examine the systems more closely. Several measures as evaluation basis were specified, and the systems were selected based a set of metric outcomes using Integrated Analytic Hierarchy Process (AHP) and TOPSIS. The experimental results showed that GNUmed and OpenEMR software can provide better basis on ranking score records than other open-source EMR software packages.
Meeting the security requirements of electronic medical records in the ERA of high-speed computing

Alanazi HO, Zaidan AA, Zaidan BB, Kiah ML, Al-Bakri SH

J Med Syst, 2015 Jan;39(1):165.
PMID: 25481568 DOI: 10.1007/s10916-014-0165-3

This study has two objectives. First, it aims to develop a system with a highly secured approach to transmitting electronic medical records (EMRs), and second, it aims to identify entities that transmit private patient information without permission. The NTRU and the Advanced Encryption Standard (AES) cryptosystems are secured encryption methods. The AES is a tested technology that has already been utilized in several systems to secure sensitive data. The United States government has been using AES since June 2003 to protect sensitive and essential information. Meanwhile, NTRU protects sensitive data against attacks through the use of quantum computers, which can break the RSA cryptosystem and elliptic curve cryptography algorithms. A hybrid of AES and NTRU is developed in this work to improve EMR security. The proposed hybrid cryptography technique is implemented to secure the data transmission process of EMRs. The proposed security solution can provide protection for over 40 years and is resistant to quantum computers. Moreover, the technique provides the necessary evidence required by law to identify disclosure or misuse of patient records. The proposed solution can effectively secure EMR transmission and protect patient rights. It also identifies the source responsible for disclosing confidential patient records. The proposed hybrid technique for securing data managed by institutional websites must be improved in the future.
Design and develop a video conferencing framework for real-time telemedicine applications using secure group-based communication architecture

Mat Kiah ML, Al-Bakri SH, Zaidan AA, Zaidan BB, Hussain M

J Med Syst, 2014 Oct;38(10):133.
PMID: 25199651 DOI: 10.1007/s10916-014-0133-y

One of the applications of modern technology in telemedicine is video conferencing. An alternative to traveling to attend a conference or meeting, video conferencing is becoming increasingly popular among hospitals. By using this technology, doctors can help patients who are unable to physically visit hospitals. Video conferencing particularly benefits patients from rural areas, where good doctors are not always available. Telemedicine has proven to be a blessing to patients who have no access to the best treatment. A telemedicine system consists of customized hardware and software at two locations, namely, at the patient's and the doctor's end. In such cases, the video streams of the conferencing parties may contain highly sensitive information. Thus, real-time data security is one of the most important requirements when designing video conferencing systems. This study proposes a secure framework for video conferencing systems and a complete management solution for secure video conferencing groups. Java Media Framework Application Programming Interface classes are used to design and test the proposed secure framework. Real-time Transport Protocol over User Datagram Protocol is used to transmit the encrypted audio and video streams, and RSA and AES algorithms are used to provide the required security services. Results show that the encryption algorithm insignificantly increases the video conferencing computation time.
MIRASS: medical informatics research activity support system using information mashup network

Kiah ML, Zaidan BB, Zaidan AA, Nabi M, Ibraheem R

J Med Syst, 2014 Apr;38(4):37.
PMID: 24700079 DOI: 10.1007/s10916-014-0037-x

The advancement of information technology has facilitated the automation and feasibility of online information sharing. The second generation of the World Wide Web (Web 2.0) enables the collaboration and sharing of online information through Web-serving applications. Data mashup, which is considered a Web 2.0 platform, plays an important role in information and communication technology applications. However, few ideas have been transformed into education and research domains, particularly in medical informatics. The creation of a friendly environment for medical informatics research requires the removal of certain obstacles in terms of search time, resource credibility, and search result accuracy. This paper considers three glitches that researchers encounter in medical informatics research; these glitches include the quality of papers obtained from scientific search engines (particularly, Web of Science and Science Direct), the quality of articles from the indices of these search engines, and the customizability and flexibility of these search engines. A customizable search engine for trusted resources of medical informatics was developed and implemented through data mashup. Results show that the proposed search engine improves the usability of scientific search engines for medical informatics. Pipe search engine was found to be more efficient than other engines.
The landscape of research on smartphone medical apps: Coherent taxonomy, motivations, open challenges and recommendations

Hussain M, Al-Haiqi A, Zaidan AA, Zaidan BB, Kiah ML, Anuar NB, et al.

Comput Methods Programs Biomed, 2015 Dec;122(3):393-408.
PMID: 26412009 DOI: 10.1016/j.cmpb.2015.08.015

To survey researchers' efforts in response to the new and disruptive technology of smartphone medical apps, mapping the research landscape form the literature into a coherent taxonomy, and finding out basic characteristics of this emerging field represented on: motivation of using smartphone apps in medicine and healthcare, open challenges that hinder the utility, and the recommendations to improve the acceptance and use of medical apps in the literature.
Fulltext An evaluation and selection problems of OSS-LMS packages

Abdullateef BN, Elias NF, Mohamed H, Zaidan AA, Zaidan BB

Springerplus, 2016;5:248.
PMID: 27064567 DOI: 10.1186/s40064-016-1828-y

The evaluation and selection of inappropriate open source software in learning management system (OSS-LMS) packages adversely affect the business processes and functions of an organization. Thus, comprehensive insights into the evaluation and selection of OSS-LMS packages are presented in this paper on the basis of three directions. First, available OSS-LMSs are ascertained from published papers. Second, the criteria for evaluating OSS-LMS packages are specified.according to two aspects: the criteria are identified and established, followed by a crossover between them to highlight the gaps between the evaluation criteria for OSS-LMS packages and the selection problems. Third, the abilities of selection methods that appear fit to solve the problems of OSS-LMS packages based on the multi-criteria evaluation and selection problem are discussed to select the best OSS-LMS packages. Results indicate the following: (1) a list of active OSS-LMS packages; (2) the gaps on the evaluation criteria used for LMS and other problems (consisting of main groups with sub-criteria); (3) use of multi-attribute or multi-criteria decision-making (MADM/MCDM) techniques in the framework of the evaluation and selection of the OSS in education as recommended solutions.
Mobile Patient Monitoring Systems from a Benchmarking Aspect: Challenges, Open Issues and Recommended Solutions

Almahdi EM, Zaidan AA, Zaidan BB, Alsalem MA, Albahri OS, Albahri AS

J Med Syst, 2019 May 29;43(7):207.
PMID: 31144129 DOI: 10.1007/s10916-019-1336-z

This paper presents comprehensive insights into mobile patient monitoring systems (MPMSs) from evaluation and benchmarking aspects on the basis of two critical directions. The current evaluation criteria of MPMSs based on the architectural components of MPMSs and possible solutions are discussed. This review highlights four serious issues, namely, multiple evaluation criteria, criterion importance, unmeasurable criteria and data variation, in MPMS benchmarking. Multicriteria decision-making (MCDM) analysis techniques are proposed as effective solutions to solve these issues from a methodological aspect. This methodological aspect involves a framework for benchmarking MPMSs on the basis of MCDM to rank available MPMSs and select a suitable one. The benchmarking framework is discussed in four steps. Firstly, pre-processing and identification procedures are presented. Secondly, the procedure of weight calculation based on the best-worst method (BWM) is described. Thirdly, the development of a benchmark framework by using the VIKOR method is introduced. Lastly, the proposed framework is validated.
Mobile-Based Patient Monitoring Systems: A Prioritisation Framework Using Multi-Criteria Decision-Making Techniques

Almahdi EM, Zaidan AA, Zaidan BB, Alsalem MA, Albahri OS, Albahri AS

J Med Syst, 2019 Jun 06;43(7):219.
PMID: 31172296 DOI: 10.1007/s10916-019-1339-9

This study presents a prioritisation framework for mobile patient monitoring systems (MPMSs) based on multicriteria analysis in architectural components. This framework selects the most appropriate system amongst available MPMSs for the telemedicine environment. Prioritisation of MPMSs is a challenging task due to (a) multiple evaluation criteria, (b) importance of criteria, (c) data variation and (d) unmeasurable values. The secondary data presented as the decision evaluation matrix include six systems (namely, Yale-National Aeronautics and Space Administration (NASA), advanced health and disaster aid network, personalised health monitoring, CMS, MobiHealth and NTU) as alternatives and 13 criteria (namely, supported number of sensors, sensor front-end (SFE) communication, SFE to mobile base unit (MBU) communications, display of biosignals on the MBU, storage of biosignals on the MBU, intra-body area network (BAN) communication problems, extra-BAN communication problems, extra-BAN communication technology, extra-BAN communication protocols, back-end system communication technology, intended geographic area of use, end-to-end security and reported trial problems) based on the architectural components of MPMSs. These criteria are adopted from the most relevant studies and are found to be applicable to this study. The prioritisation framework is developed in three stages. (1) The unmeasurable values of the MPMS evaluation criteria in the adopted decision evaluation matrix based on expert opinion are represented by using the best-worst method (BWM). (2) The importance of the evaluation criteria based on the architectural components of the MPMS is determined by using the BWM. (3) The VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) method is utilised to rank the MPMSs according to the determined importance of the evaluation criteria and the adopted decision matrix. For validation, mean ± standard deviation is used to verify the similarity of systematic prioritisations objectively. The following results are obtained. (1) The BWM represents the unmeasurable values of the MPMS evaluation criteria. (2) The BWM is suitable for weighing the evaluation criteria based on the architectural components of the MPMS. (3) VIKOR is suitable for solving the MPMS prioritisation problem. Moreover, the internal and external VIKOR group decision making are approximately the same, with the best MPMS being 'Yale-NASA' and the worst MPMS being 'NTU'. (4) For the objective validation, remarkable differences are observed between the group scores, which indicate the similarity of internal and external prioritisation results.
A Systematic Review for Enabling of Develop a Blockchain Technology in Healthcare Application: Taxonomy, Substantially Analysis, Motivations, Challenges, Recommendations and Future Direction

Hussien HM, Yasin SM, Udzir SNI, Zaidan AA, Zaidan BB

J Med Syst, 2019 Sep 14;43(10):320.
PMID: 31522262 DOI: 10.1007/s10916-019-1445-8

Blockchain in healthcare applications requires robust security and privacy mechanism for high-level authentication, interoperability and medical records sharing to comply with the strict legal requirements of the Health Insurance Portability and Accountability Act of 1996. Blockchain technology in the healthcare industry has received considerable research attention in recent years. This study conducts a review to substantially analyse and map the research landscape of current technologies, mainly the use of blockchain in healthcare applications, into a coherent taxonomy. The present study systematically searches all relevant research articles on blockchain in healthcare applications in three accessible databases, namely, ScienceDirect, IEEE and Web of Science, by using the defined keywords 'blockchain', 'healthcare' and 'electronic health records' and their variations. The final set of collected articles related to the use of blockchain in healthcare application is divided into three categories. The first category includes articles (i.e. 43/58 scientific articles) that attempted to develop and design healthcare applications integrating blockchain, particularly those on new architecture, system designs, framework, scheme, model, platform, approach, protocol and algorithm. The second category includes studies (i.e., 6/58 scientific articles) that attempted to evaluate and analyse the adoption of blockchain in the healthcare system. Finally, the third category comprises review and survey articles (i.e., 6/58 scientific articles) related to the integration of blockchain into healthcare applications. The final articles for review are discussed on the basis of five aspects: (1) year of publication, (2) nationality of authors, (3) publishing house or journal, (4) purpose of using blockchain in health applications and the corresponding contributions and (5) problem types and proposed solutions. Additionally, this study provides identified motivations, open challenges and recommendations on the use of blockchain in healthcare applications. The current research contributes to the literature by providing a detailed review of feasible alternatives and identifying the research gaps. Accordingly, researchers and developers are provided with appealing opportunities to further develop decentralised healthcare applications through a comprehensive discussion of about the importance of blockchain and its integration into various healthcare applications.
A distributed framework for health information exchange using smartphone technologies

Abdulnabi M, Al-Haiqi A, Kiah MLM, Zaidan AA, Zaidan BB, Hussain M

J Biomed Inform, 2017 05;69:230-250.
PMID: 28433825 DOI: 10.1016/j.jbi.2017.04.013

Nationwide health information exchange (NHIE) continues to be a persistent concern for government agencies, despite the many efforts and the conceived benefits of sharing patient data among healthcare providers. Difficulties in ensuring global connectivity, interoperability, and concerns on security have always hampered the government from successfully deploying NHIE. By looking at NHIE from a fresh perspective and bearing in mind the pervasiveness and power of modern mobile platforms, this paper proposes a new approach to NHIE that builds on the notion of consumer-mediated HIE, albeit without the focus on central health record banks. With the growing acceptance of smartphones as reliable, indispensable, and most personal devices, we suggest to leverage the concept of mobile personal health records (PHRs installed on smartphones) to the next level. We envision mPHRs that take the form of distributed storage units for health information, under the full control and direct possession of patients, who can have ready access to their personal data whenever needed. However, for the actual exchange of data with health information systems managed by healthcare providers, the latter have to be interoperable with patient-carried mPHRs. Computer industry has long ago solved a similar problem of interoperability between peripheral devices and operating systems. We borrow from that solution the idea of providing special interfaces between mPHRs and provider systems. This interface enables the two entities to communicate with no change to either end. The design and operation of the proposed approach is explained. Additional pointers on potential implementations are provided, and issues that pertain to any solution to implement NHIE are discussed.
Fulltext A Review on Systems-Based Sensory Gloves for Sign Language Recognition State of the Art between 2007 and 2017

Ahmed MA, Zaidan BB, Zaidan AA, Salih MM, Lakulu MMB

Sensors (Basel), 2018 Jul 09;18(7).
PMID: 29987266 DOI: 10.3390/s18072208

Loss of the ability to speak or hear exerts psychological and social impacts on the affected persons due to the lack of proper communication. Multiple and systematic scholarly interventions that vary according to context have been implemented to overcome disability-related difficulties. Sign language recognition (SLR) systems based on sensory gloves are significant innovations that aim to procure data on the shape or movement of the human hand. Innovative technology for this matter is mainly restricted and dispersed. The available trends and gaps should be explored in this research approach to provide valuable insights into technological environments. Thus, a review is conducted to create a coherent taxonomy to describe the latest research divided into four main categories: development, framework, other hand gesture recognition, and reviews and surveys. Then, we conduct analyses of the glove systems for SLR device characteristics, develop a roadmap for technology evolution, discuss its limitations, and provide valuable insights into technological environments. This will help researchers to understand the current options and gaps in this area, thus contributing to this line of research.

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