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  1. Nugroho H, Fadzil MH, Yap VV, Norashikin S, Suraiya HH
    PMID: 18002737
    In this paper, we describe an image processing scheme to analyze and determine areas of skin that have undergone repigmentation in particular, during the treatment of vitiligo. In vitiligo cases, areas of skin become pale or white due to the lack of skin pigment called melanin. Vitiligo treatment causes skin repigmentation resulting in a normal skin color. However, it is difficult to determine and quantify the amount of repigmentation visually during treatment because the repigmentation progress is slow and moreover changes in skin color can only be discerned over a longer time frame typically 6 months. Here, we develop a digital image analysis scheme that can identify and determine vitiligo skin areas and repigmentation progression on a shorter time period. The technique is based on principal component analysis and independent component analysis which converts the RGB skin image into a skin image that represent skin areas due to melanin and haemoglobin only, followed by segmentation process. Vitiligo skin lesions are identified as skin areas that lack melanin (non-melanin areas). In the initial studies of 4 patients, the method has been able to quantify repigmentation in vitiligo lesion. Hence it is now possible to determine repigmentation progression objectively and treatment efficacy on a shorter time cycle.
  2. Khan MB, Nisar H, Ng CA, Lo PK, Yap VV
    Environ Technol, 2018 Jan;39(1):24-34.
    PMID: 28278778 DOI: 10.1080/09593330.2017.1293166
    The state of activated sludge wastewater treatment process (AS WWTP) is conventionally identified by physico-chemical measurements which are costly, time-consuming and have associated environmental hazards. Image processing and analysis-based linear regression modeling has been used to monitor the AS WWTP. But it is plant- and state-specific in the sense that it cannot be generalized to multiple plants and states. Generalized classification modeling for state identification is the main objective of this work. By generalized classification, we mean that the identification model does not require any prior information about the state of the plant, and the resultant identification is valid for any plant in any state. In this paper, the generalized classification model for the AS process is proposed based on features extracted using morphological parameters of flocs. The images of the AS samples, collected from aeration tanks of nine plants, are acquired through bright-field microscopy. Feature-selection is performed in context of classification using sequential feature selection and least absolute shrinkage and selection operator. A support vector machine (SVM)-based state identification strategy was proposed with a new agreement solver module for imbalanced data of the states of AS plants. The classification results were compared with state-of-the-art multiclass SVMs (one-vs.-one and one-vs.-all), and ensemble classifiers using the performance metrics: accuracy, recall, specificity, precision, F measure and kappa coefficient (κ). The proposed strategy exhibits better results by identification of different states of different plants with accuracy 0.9423, and κ 0.6681 for the minority class data of bulking.
  3. Cheah KH, Nisar H, Yap VV, Lee CY, Sinha GR
    J Healthc Eng, 2021;2021:5599615.
    PMID: 33859808 DOI: 10.1155/2021/5599615
    Emotion is a crucial aspect of human health, and emotion recognition systems serve important roles in the development of neurofeedback applications. Most of the emotion recognition methods proposed in previous research take predefined EEG features as input to the classification algorithms. This paper investigates the less studied method of using plain EEG signals as the classifier input, with the residual networks (ResNet) as the classifier of interest. ResNet having excelled in the automated hierarchical feature extraction in raw data domains with vast number of samples (e.g., image processing) is potentially promising in the future as the amount of publicly available EEG databases has been increasing. Architecture of the original ResNet designed for image processing is restructured for optimal performance on EEG signals. The arrangement of convolutional kernel dimension is demonstrated to largely affect the model's performance on EEG signal processing. The study is conducted on the Shanghai Jiao Tong University Emotion EEG Dataset (SEED), with our proposed ResNet18 architecture achieving 93.42% accuracy on the 3-class emotion classification, compared to the original ResNet18 at 87.06% accuracy. Our proposed ResNet18 architecture has also achieved a model parameter reduction of 52.22% from the original ResNet18. We have also compared the importance of different subsets of EEG channels from a total of 62 channels for emotion recognition. The channels placed near the anterior pole of the temporal lobes appeared to be most emotionally relevant. This agrees with the location of emotion-processing brain structures like the insular cortex and amygdala.
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