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  1. Syed Mohamed AMF, Wei TZ, Sean CJ, Rosli TI
    Spec Care Dentist, 2023;43(5):554-560.
    PMID: 36269010 DOI: 10.1111/scd.12790
    OBJECTIVE: To evaluate the prevalence and significance of the malocclusion traits and orthodontic treatment needs of Down syndrome (DS) subjects with matched non-syndromic (NS) controls.

    METHODOLOGY: This cross-sectional study involved 222 subjects (50% DS, 50% NS) who were matched by gender and age. The casts were digitized into three-dimensional images. These images were used alongside the ten occlusal characteristics of the Dental Aesthetic Index (DAI) to determine malocclusion severity and the need for orthodontic treatment.

    RESULTS: There were 58 (52.3%) females and 53 (47.7%) males with a mean age of 18.4 ± 8.4 years in both groups. The most common and significant (p  30). The DS showed some impact of malocclusion traits components of the DAI.

    CONCLUSION: The occurrence of malocclusion was higher in DS, implying a higher need for orthodontic treatments than for NS subjects.

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