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Genus Promalactis Meyrick, 1908 (Lepidoptera: Oecophoridae) from Malaysia, with description of three new species

Liu C, Wang S

Zootaxa, 2020 Mar 23;4755(1):zootaxa.4755.1.2.
PMID: 32230193 DOI: 10.11646/zootaxa.4755.1.2

Based on the specimens collected in Mt. Trusmadi, Sabah, Malaysia, three new species of the genus Promalactis are described: P. clavivalvata sp. nov., P. abasiloba sp. nov. and P. trusmadiensis sp. nov. In addition, females of three previously known species (P. folivalva Wang, 2018, P. sectoralis Wang et al., 2013 and P. trigonilobata Wang, 2018) are described for the first time. Two species (P. sectoralis Wang et al., 2013 and P. pileata Wang, 2019) are newly recorded for Malaysia. Images of both adults and genitalia of the new species and the genitalia of the newly described females are provided.
Fulltext Pedunculated subcutaneous lipoma in the popliteal fossa causing eczema

Wang SY, Ong KO

Med J Malaysia, 2015 Feb;70(1):33-5.
PMID: 26032527

Pedunculated subcutaneous lipoma in the popliteal fossa extending through the superficial fascia causing chronic irritant dermatitis of the adjacent skin with "psoriatic-like" plaque. To the author's knowledge, no similar case has been reported in the literature.
Taxonomic study of the genus Promalactis Meyrick, 1908 from Southeast Asia (Lepidoptera: Oecophoridae)

Wang S, Du Z, Li H

Zootaxa, 2013;3669:401-55.
PMID: 26312350

The genus Proinalactis Meyrick, 1908 is reviewed in Southeast Asia. Twenty-seven new species are described based on the specimens collected in Malaysia, Thailand, Brunei, Burma, Philippines. The new species include P. alveiformis sp. nov., P. angusta sp. nov., P. bruneiensis sp. nov., P. conicispinalis sp. nov., P. ellipsoidea sp. nov., P. exiliprocessa sp. nov., P. extumida sp. nov., P. fascisetacea sp. nov., P. flagellaris sp. nov., P. foraininulata sp. nov., P. fortijuxtalis sp. nov., P. lancea sp. nov., P. latuncata sp. nov., P. longisaccata sp. nov., P. lophacantha sp. nov., P. medispinata sp. nov., P. palmifolia sp. nov., P. pectinifera sp. nov., P.sectoralis sp. nov., P. semiovata sp. nov., P. sinualis sp. nov., P. spinosicostalis sp. nov., P. strena sp. nov., P. superimposita sp. nov., P. truncatapicalis sp. nov., P. undulata sp. nov. and P. vulvida sp. nov. Promalactis parasuzukiella Wang, 2006 and P. simniliflora Wang, 2006 are recorded from Southeast Asia for the first time. Three species described by Lvovsky are fully redescribed. Images of adults and genitalia are provided, along with a check list of 71 species from Southeast Asia.
Rapid thin-layer chromatographic semiquantification of morphine in urine via dabsylation: comparison with EMIT and thin-layer chromatographic-iodoplatinate methods

Wang SY, Tham SY, Poon MK

Clin Chem, 1989 Feb;35(2):329-30.
PMID: 2644060
Cutaneous Larva Migrans Associated With Löffler's Syndrome in a 6-Year-Old Boy

Wang S, Xu W, Li LF

Pediatr Infect Dis J, 2017 Sep;36(9):912-914.
PMID: 28338526 DOI: 10.1097/INF.0000000000001593

Cutaneous larva migrans is a frequent dermatologic problem among travelers in tropical areas, but its association with Löffler's syndrome is an extremely rare condition, particularly in children. Here, we describe a 6-year-old boy presenting cutaneous larva migrans associated with Löffler's syndrome.
Seven new species of the genus Deltoplastis Meyrick, 1925 (Lepidoptera: Lecithoceridae)

Yu S, Park KT, Wang S

Zootaxa, 2019 Jun 18;4619(1):zootaxa.4619.1.7.
PMID: 31716319 DOI: 10.11646/zootaxa.4619.1.7

Seven new species of the genus Deltoplastis Meyrick are described: D. acutangulata Wang et Yu, sp. nov., D. anatoliana Wang et Park, sp. nov., D. multidentalis Wang et Yu, sp. nov. and D. similihoristis Wang et Yu, sp. nov. from China; D. aculeata Wang et Yu, sp. nov. and D. spatuliunca Wang et Yu, sp. nov. from Malaysian Borneo; and D. ovidiscalis Park et Wang, sp. nov. from Vietnam. Deltoplastis horistis (Meyrick, 1910) is newly recorded in China and its female is described for the first time. Images of adults and genitalia of the new species are provided.
Thermal death kinetics of Mediterranean, Malaysian, melon, and oriental fruit fly (Diptera: Tephritidae) eggs and third instars

Armstrong JW, Tang J, Wang S

J Econ Entomol, 2009 Apr;102(2):522-32.
PMID: 19449631

The late-aged egg and third-instar life stages of laboratory-reared Malaysian fruit fly, Bactrocera latifrons (Hendel); Mediterranean fruit fly, Ceratitis capitata (Wiedemann); melon fly, B. cucurbitae Coquillett; and oriental fruit fly, B. dorsalis (Hendel), (Diptera: Tephritidae); and the third instars of wild Mediterranean fruit fly were exposed to thermal treatments. A heating block system was used to determine the thermal death kinetics of the four fruit fly species. Treatments consisted of heating the fruit fly life stages to 44, 46, 48, and 50 degrees C and holding for different times ranging from 0 to 120 min depending on the thermal mortality response and time required to obtain 100% mortality for each species and life stage. The 0.5-order kinetic model had the best fit to the survival ratio for all the treatment temperatures and was used to predict lethal times. The thermal death time (TDT) curves showed a tolerance order of Mediterranean fruit fly eggs < or = third instars at 44, 46, and 50 degrees C, third instars < or = eggs at 48 degrees C, and wild third instars < the laboratory-reared third instars. Comparison between Mediterranean fruit fly third instar thermotolerance from Hawaii and Israel showed that Israel Mediterranean fruit fly was more thermotolerant. A comparison of minimum treatment times at a given temperature required to obtain 100% mortality of laboratory-reared Malaysian, Mediterranean (Hawaii and Israel strains), melon, Mexican, and oriental fruit fly eggs or third instars and wild Mediterranean fruit fly (Hawaii strain) eggs or third instars showed that oriental fruit fly was the most thermotolerant among the third instars, and the difference in heat tolerance between third instars and eggs was negligible at 50 degrees C.
Fulltext Motivations Influencing Alipay Users to Participate in the Ant Forest Campaign: An Empirical Study

Wang S, Ibrahiem MH, Li M

Int J Environ Res Public Health, 2022 Dec 18;19(24).
PMID: 36554915 DOI: 10.3390/ijerph192417034

As one of the largest payment platforms in China, Alipay, launched a green behavior project called Ant Forest. The purpose of taking this initiative by Alipay is to make the world greener. This mobile application has motivated many users to plant millions of trees. However, minimal studies have been conducted to empirically disclose the factors that motivate Alipay users to participate in Ant Forest. A mixed-method approach is used to examine the factors influencing Alipay users to participate in Ant Forest and the level of satisfaction they got from it. The qualitative method was carried out through a structured questionnaire from 400 Alipay users and qualitative data from 20 users who have applied to Ant Forest and successfully planted trees. Additionally, alongside the mixed method employed to rationalize the relationship highlighted, a multiple regression model was employed to predict the value of a dependent variable (level of satisfaction) based on the value of several independent variables (namely, number of years engaged with Ant Forest activities, age, gender, profession, and education). The empirical results show that intrinsic motivations (enjoyment, social interaction, fulfilment, altruism) and extrinsic motivations (external rewards, competition) influence Alipay users to participate in the Ant Forest project. Further insights are presented in the concluding section for all stakeholders for environmental sustainability among the users of Alipay.
Fulltext Impacts of family care for children and the elderly on women's employment: evidence from rural China

Miao X, Han J, Wang S, Han B

Front Psychol, 2023;14:1208749.
PMID: 37786482 DOI: 10.3389/fpsyg.2023.1208749

INTRODUCTION: China's traditional culture makes rural women and men take on different family responsibilities.
METHODS: Use "China Family Panel Studies" (CFPS) data and build Logit and propensity score matching models to empirically study the impact of children care and elderly care on rural married women going out to work. And explore the welfare effects of basic education public services in helping rural women take care of their families.
RESULTS: The results show that caring for children has a significant hindering effect on rural married women's job hunting. Especially for those in low-income families, the employment inhibition is most significant among women aged 20-30 with multiple children. Contrary to previous cognition, supporting the elderly has a certain weak stimulating effect. The kindergarten public services in rural areas can help women take care of their children and relieve their work pressure. The primary school public services have not played a role in alleviating them.
DISCUSSION: This shows that there are still a large number of female laborers in rural China who are unable to go out to work due to family care. The improvement of rural basic education public services can promote more rural women going out to work. This finding will provide a policy reference for the introduction of a formal care system and the establishment of basic education public services in China.
Trends in age-standardized incidence rates of depression in adolescents aged 10-24 in 204 countries and regions from 1990 to 2019

Hua Z, Wang S, Yuan X

J Affect Disord, 2024 Apr 01;350:831-837.
PMID: 38242215 DOI: 10.1016/j.jad.2024.01.009

BACKGROUND: The objective of this study was to provide a comprehensive analysis of the spatial distribution and temporal trends in the age-standardized incidence rates (ASIRs) of depression in adolescents aged 10-24 worldwide.
METHODS: Data from the Global Burden of Disease Study (GBD) 2019 were analyzed, adopting Sawyer's broad definition of adolescence encompassing ages 10 to 24. Estimated annual percentage changes (EAPCs) were used to assess temporal trends.
RESULTS: Globally, from 1990 to 2019, there was a decrease in the ASIR of depression in adolescents (EAPC = -0.23). Notably, this decrease was more pronounced in female adolescents compared to their male counterparts (EAPC = -0.12 and - 0.29, respectively). Conversely, high Sociodemographic Index (SDI) regions experienced a significant increase in the ASIR of depression among adolescents (EAPC = 0.87). Furthermore, it is worth mentioning that individuals aged 20-24 exhibited the highest incidence rate for depression followed by those aged 15-19 and then those aged 10-14. The largest increases in the ASIRs of depression occurred in High-income North America (EAPC = 1.19) and Malaysia (EAPC = 2.4), respectively.
LIMITATIONS: Mathematical models were used to reconstruct and adjust data of different qualities, which might have introduced bias.
CONCLUSIONS: The global burden of disease for depression among adolescents aged 10-24 years declined from 1990 to 2019. Special attention must be paid to older adolescents and areas with higher SDIs.
Spatial effects of market integration on the industrial agglomeration of agricultural products: evidence from China

Miao X, Han J, Wang S, Li X

Environ Sci Pollut Res Int, 2023 Aug;30(36):84949-84971.
PMID: 37392303 DOI: 10.1007/s11356-023-28303-4

The spatial effects of agricultural market integration on industrial agglomeration are an important field of regional economic. This paper collected the data of agricultural market integration and industrial agglomeration in 31 provinces in China from 2010 to 2019, analyzed the spatial effects of the two by constructing a dynamic spatial Dubin model, and explored its long-term and short-term effects of the spatial effects. The results show the following: (1) the primary terms of agricultural market integration were negative and the secondary terms were positive. The impact of agricultural market integration on local industrial agglomeration had a "U-shaped" characteristic. Whether in the short-term or long-term, there was a significant direct effect of "suppression to promotion." (2) The agricultural market integration had a spatial spillover effect on industrial agglomeration in the neighboring areas. This effect had an "inverted U-shaped" characteristic. Whether in the short-term or long-term, there was a prominent spatial spillover effect of "promotion to suppression." (3) For direct effects, the short-term direct effects of agricultural market integration on industrial agglomeration were - 0.0452 and 0.0077, and the long-term direct effects were - 0.2430 and 0.0419. For spatial spillover effects, the short-term spatial spillover effects were 0.0983 and - 0.0179, and the long-term spatial spillover effects were 0.4554 and - 0.0827. The long-term effects were greater than the short-term effects. This paper provides empirical evidence for the effects of agricultural market integration on industrial agglomeration in different regions, and exploring the development of agricultural agglomeration in the long-term.
Fulltext Spatio-temporal variations in wheat aphid populations and their natural enemies in four agro-ecological zones of Pakistan

Faheem M, Saeed S, Sajjad A, Wang S, Ali A

PLoS One, 2019;14(9):e0222635.
PMID: 31568475 DOI: 10.1371/journal.pone.0222635

Aphids are major pests of wheat crop in Pakistan inflicting considerable economic losses. A better knowledge of landscape scale spatial distribution of aphids and their natural enemies could be used to improve integrated pest management programs. Therefore, the present study aimed to document spatio-temporal variations in populations of wheat aphids and their natural enemies in Pakistan. The 2-year survey study was carried out at ten experimental farms located in five districts of four contrasted agro-ecological zones of eastern Pakistan (Punjab area) i.e. District Chakwal in arid zone, Gujranwala in rice-cropped zone, Faisalabad in central mixed-cropped zone, and Khanewal and Multan in cotton-cropped zone. The dominant aphid species i.e. Schizaphis graminum, Rhopalosiphum padi, R. maidis and Sitobion avenae varied significantly among the five districts surveyed. The population of S. graminum was observed more abundant in arid, R. padi in rice, S. avenae in aird and rice, and R. maidis in cotton-I zones. Aphids ended their population dynamics on 25th March in central mixed-cropped zone and 12th April in other three zones. Various species of natural enemies, mainly Coccinella septumpunctata, C. undecimpunctata, Menochilus sexmaculata, Chrysoperla carnea, Syrphidae and parasitoid mummies were inconsistently observed in four agro-ecological zones. The population of C. septumpunctata, was observed more abundant in rice zone, C. undecimpunctata and C. carnea in cotton-I and arid zones, M. sexmaculata in cotton-I and II zones, Syrphidae in cotton-I zone and parasitoid mummies in rice and arid zones. There were no clear relationships between aphid and the natural enemy populations. The present study may serve as a baseline regarding distribution of wheat aphids and their natural enemies and the results provided insights for further studies on the potential top-down (natural enemies) versus bottom-up (fertilization and irrigation regimes) forces in management of wheat aphids in eastern Pakistan.
Immunodetection of urinary C-terminal telopeptide fragment of type II collagen: An osteoarthritis biomarker analysis

Wang S, Su S, Yu C, Gopinath SCB, Yang Z

Biotechnol Appl Biochem, 2021 Aug;68(4):726-731.
PMID: 32621620 DOI: 10.1002/bab.1981

The urinary C-terminal telopeptide fragment of type II collagen (uCTX-II) has been reported as the efficient blood-based biomarker for osteoarthritis, which affects knees, hands, spine, and hips. This study reports a sensing strategy with antibody-conjugated gold nanoparticles (GNP) on an interdigitated electrode (IDE) to determine uCTX-II. The GNP-antibody complex was chemically immobilized on the IDE surface through the amine linker. uCTX-II was determined by monitoring the alteration in current upon interacting the GNP-complexed antibody. This strategy was improved the detection by attracting higher uCTX-II molecules, and the detection limit falls in the range of 10-100 pM with an acceptable regression value [y = 0.6254x - 0.4073, R² = 0.9787]. The sensitivity of the detection was recognized at 10 pM. Additionally, upon increasing the uCTX-II concentration, the current changes were increased in a linear fashion. Control detection with nonimmune antibody and control protein do not increase the current level, confirming the specific detection of uCTX-II. This method of detection helps in diagnosing osteoarthritis and its follow-up treatment.
Neutral and ionizable per-and polyfluoroalkyl substances in the urban atmosphere: Occurrence, sources and transport

Wang S, Lin X, Li Q, Liu C, Li Y, Wang X

Sci Total Environ, 2022 Feb 09;823:153794.
PMID: 35150692 DOI: 10.1016/j.scitotenv.2022.153794

In the atmosphere, the photodegradation of neutral per-and polyfluoroalkyl substances (n-PFASs) is a source of ionizable PFASs (i-PFASs). However, they are not frequently simultaneously analyzed to study their transport and sources. In this study, n-PFASs and i-PFASs were simultaneously analyzed in the atmosphere of China, Japan and Malaysia to investigate the occurrence, seasonal variations, sources and transport. Results showed that n-PFASs ranged from 4.8 to 1400 pg m-3, with an average value of 170 pg m-3, and 8:2 fluorotelomer alcohol (8:2 FTOH) was the most abundant compound. i-PFASs ranged from 3.7 to 330 pg m-3, with an average value of 49 pg m-3, and perfluorobutanoic acid (PFBA) had the highest concentration. Generally, airborne PFASs had a decreasing gradient from cities with high population density toward less industrialized sites. i-PFASs exhibited significantly (P < 0.05) seasonal variations, which were higher in the summer. 8:2 FTOH and 10:2 FTOH had significant (P < 0.05) positive correlations with perfluorooctanoic acid and perfluorodecanoic acid, suggesting that they had same sources, such as co-emission and photodegradation of FTOHs. Urumqi and Selangor were far away from industry, and high percentages (>95%) but low concentrations of PFBA were found in these cities, indicating the long-range atmospheric transport of PFBA due to its high volatility. The Summer Monsoon may promote the transport of high concentrations of PFAS from coastal cities to inland cities.
Fulltext An improved arithmetic optimization algorithm with forced switching mechanism for global optimization problems

Zheng R, Jia H, Abualigah L, Liu Q, Wang S

Math Biosci Eng, 2022 01;19(1):473-512.
PMID: 34903000 DOI: 10.3934/mbe.2022023

Arithmetic optimization algorithm (AOA) is a newly proposed meta-heuristic method which is inspired by the arithmetic operators in mathematics. However, the AOA has the weaknesses of insufficient exploration capability and is likely to fall into local optima. To improve the searching quality of original AOA, this paper presents an improved AOA (IAOA) integrated with proposed forced switching mechanism (FSM). The enhanced algorithm uses the random math optimizer probability (RMOP) to increase the population diversity for better global search. And then the forced switching mechanism is introduced into the AOA to help the search agents jump out of the local optima. When the search agents cannot find better positions within a certain number of iterations, the proposed FSM will make them conduct the exploratory behavior. Thus the cases of being trapped into local optima can be avoided effectively. The proposed IAOA is extensively tested by twenty-three classical benchmark functions and ten CEC2020 test functions and compared with the AOA and other well-known optimization algorithms. The experimental results show that the proposed algorithm is superior to other comparative algorithms on most of the test functions. Furthermore, the test results of two training problems of multi-layer perceptron (MLP) and three classical engineering design problems also indicate that the proposed IAOA is highly effective when dealing with real-world problems.
Fulltext Entropy-based financial asset pricing: Evidence from Pakistan

Wang S, Khan SA, Munir M, Alhajj R, Khan YA

PLoS One, 2022;17(12):e0278236.
PMID: 36548250 DOI: 10.1371/journal.pone.0278236

Entropy is an alternative measure to calculate the risk, simplify the portfolios and equity risk premium. It has higher explanatory power than capital asset price model (CAPM) beta. The comparison of Entropy and CAPM beta provide in depth analysis about the explanatory power of the model that in turn help investor to make right investment decisions that minimizes risk. In this context, this study aims to compare Shannon and Rennyi Entropies with the CAPM beta for measuring the risk. Ordinary Least square approach has been utilized using a dataset of 67 enterprises registered in Pakistan Stock exchange. The comparative analysis of CAPM beta and entropy has been carried out with the R2 parameters. The result indicates that entropy has more explanatory power as compare to CAPM beta's explanatory power, and this turns out to be the best option to evaluate the risk performances. The result implies that an investor should make the best investment decision by choosing an enterprise that provide with good returns at minimum risk based on entropy technique.
Fulltext Why Do Some Consumers Still Prefer In-Store Shopping? An Exploration of Online Shopping Cart Abandonment Behavior

Wang S, Ye Y, Ning B, Cheah JH, Lim XJ

Front Psychol, 2021;12:829696.
PMID: 35126270 DOI: 10.3389/fpsyg.2021.829696

Shopping cart abandonment remains a challenge for many e-retailers despite the continued growth of the e-commerce industry worldwide. However, the issue of online shopping cart abandonment (OSCA) has not been explored extensively in the literature. Grounded by the stimulus-organism-response (S-O-R) model, this study explores a sequential mediation model comprising consumers' wait for lower prices as an antecedent, hesitation at checkout and OSCA as mediators, perceived transaction inconvenience as a moderator, and decision to buy from a land-based retailer (DBLR) as an outcome. An online questionnaire was designed and distributed to 883 online consumers in Mainland China. Partial least squares-structural equation modeling (PLS-SEM) was employed to analyze the survey data. The results show that waiting for lower prices positively influences hesitation at checkout, and subsequently, impacts both OSCA and DBLR. Hesitation at checkout and OSCA play sequential mediating roles in the framework path. In addition, perceived transaction inconvenience strengthens the relationship between waiting for lower prices and hesitation at checkout. Overall, this study contributes to theory and serves as a guideline for e-retailers in reducing the OSCA rate.
Fulltext The influence of the five-factor model of personality on performance in competitive sports: a review

Shuai Y, Wang S, Liu X, Kueh YC, Kuan G

Front Psychol, 2023;14:1284378.
PMID: 38162969 DOI: 10.3389/fpsyg.2023.1284378

Personality is considered to be a factor affecting athletic performance. However, inconsistency in the research results regarding size and even direction of the relationship. An evaluation of the evidence of the relationship between personality and athletic performance was conducted in order to summarize the evidence available. A systematic literature search was conducted in March 2023. Sport performance and the Big Five personality model were identified in our research. We used PubMed, Web of Science, Embase, Cochrane Library, Wang Fang (Chinese), Wei Pu (Chinese), and CNKI (Chinese) databases for the systematic literature search (Prospero registration number: CRD42022364000), screened 4,300 studies, and found 23 cross-sectional studies eligible for inclusion in this review. The results of this systematic analysis show that, besides neuroticism, openness, conscientiousness, extraversion, and agreeableness are all positively correlated with sports performance. Conscientiousness and extraversion are the two main personalities in team sports. Openness and agreeableness show different results in different sports, and it is not clear to which project they are beneficial. The value of personality as a possible predictor of athletic performance is generally positive. Therefore, professionals such as applied sports psychologists, coaching personnel, athletes, and sports administrators must comprehensively grasp the significance of personality's role in achieving success in major competitions. Considering these facts, sports practitioners should promote personality screening and personality development programs.
Fulltext (R)-Salbutamol Improves Imiquimod-Induced Psoriasis-Like Skin Dermatitis by Regulating the Th17/Tregs Balance and Glycerophospholipid Metabolism

Liu F, Wang S, Liu B, Wang Y, Tan W

Cells, 2020 02 24;9(2).
PMID: 32102363 DOI: 10.3390/cells9020511

Psoriasis is a skin disease that is characterized by a high degree of inflammation caused by immune dysfunction. (R)-salbutamol is a bronchodilator for asthma and was reported to alleviate immune system reactions in several diseases. In this study, using imiquimod (IMQ)-induced mouse psoriasis-like dermatitis model, we evaluated the therapeutic effects of (R)-salbutamol in psoriasis in vivo, and explored the metabolic pathway involved. The results showed that, compared with IMQ group, (R)-salbutamol treatment significantly ameliorated psoriasis, reversed the suppressive effects of IMQ on differentiation, extreme keratinocyte proliferation, and infiltration of inflammatory cells. Enzyme-linked immunosorbent assays (ELISA) showed that (R)-salbutamol markedly reduced the plasma levels of IL-17. Cell analysis using flow cytometry showed that (R)-salbutamol decreased the proportion of CD4+ Th17+ T cells (Th17), whereas it increased the percentage of CD25+ Foxp3+ regulatory T cells (Tregs) in the spleens. (R)-salbutamol also decreased the weight ratio of spleen to body. Furthermore, untargeted metabolomics showed that (R)-salbutamol affected three metabolic pathways, including (i) arachidonic acid metabolism, (ii) sphingolipid metabolism, and (iii) glycerophospholipid metabolism. These results demonstrated that (R)-salbutamol can alleviate IMQ-induced psoriasis through regulating Th17/Tregs cell response and glycerophospholipid metabolism. It may provide a new use of (R)-salbutamol in the management of psoriasis.
Fulltext Quaternary ammonium salt of chitosan: preparation and antimicrobial property for paper

Liu P, Meng W, Wang S, Sun Y, Ashraf MA

Open Med (Wars), 2015;10(1):473-478.
PMID: 28352739 DOI: 10.1515/med-2015-0081

A series of 2-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) was prepared by the reaction of chitosan with glycidyl trimethyl ammonium chloride. Structure of HACC was characterized by FT IR and 1H NMR spectroscopies, and it was proved that substitution reaction mainly occurs on the N element. Antimicrobial activities of HACC was examined against S. aureus, E. coli, and A. niger. Results indicatd that the inhibitory effects of HACC solutions were varied with HACC concentration, quaternization degrees, pH values, metal ions, and heat treatment. The antimicrobial properties of handsheets prepared from HACC were studied by the inhibition zone method, and the sheets had good antimicrobial properties against S. aureus and E. coli, and low inhibition rate against A. niger.

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