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  1. Fulltext Vocal fold cryptococcal granuloma: A rare occurrence in immunocompetent patient
    Zainal Abidin MR, Syed Hamzah Al-Yahya SN, Mansor M, Abdul Rahim N
    Int J Surg Case Rep, 2024 Feb;115:109228.
    PMID: 38199018 DOI: 10.1016/j.ijscr.2024.109228
    INTRODUCTION AND IMPORTANCE: Cryptoccous infection or cryptococcosis is a severe opportunistic infection occurring mainly in immunocompromised patients. Laryngeal cryptococcus infection is rare. In an immunocompetent patient, inhaled corticosteroid was reported to be a possible risk factor.

    CASE PRESENTATION: We discuss a case of right vocal fold cryptococcus infection in a healthy, immunocompetent 71-year-old man with no history of inhaled corticosteroid, presented with hoarseness and intermittent aspiration symptom for 1 year duration. Further examination showed right anterior vocal fold mass with presence of right vallecular cyst.

    CLINICAL DISCUSSION: Patient underwent direct laryngoscopy, excision of right vocal fold mass and marsupialization of vallecular cyst. Histopathological examination revealed cryptococcal infection. Patient subsequently treated with oral fluconazole 400 mg daily for 6 months. To date, hoarseness and aspiration symptoms have resolved.

    CONCLUSION: We are sharing our experience in managing laryngeal cryptococcus infection in an immunocompetent patient where the associated risk factors discussed in previous literatures are absent.

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