MyMedR

The prevelance of silicosis among granite quarry workers, of the government sector, in Peninsular Malaysia

Singh A

Med J Malaysia, 1977 Jun;31(4):277-80.

PMID: 927231

Preventive ophthalmology

Singh A

Med J Malaysia, 1977 Sep;32(1):45-7.

PMID: 609343

Uterine bleeding with an IUD requiring emergency hysterectomy

Glew S, Singh A

Adv Contracept, 1989 Mar;5(1):51-3.

PMID: 2782134

A case is described of profuse uterine bleeding with a dislodged Multiload Cu 250 intrauterine device (IUD). Multiple blood transfusions were necessary, and ultimately, an emergency hysterectomy was performed.

Fulltext Comparative evaluation of adverse drug reaction reporting forms for introduction of a spontaneous generic ADR form

Singh A, Bhatt P

J Pharmacol Pharmacother, 2012 Jul;3(3):228-32.

PMID: 23129957 DOI: 10.4103/0976-500X.99417

Despite comprehensive and stringent phases of clinical trials and surveillance efforts, unexpected and serious adverse drug reactions (ADRs) repeatedly occur after the drug is marketed. ADR reporting is an important aspect of an efficient and effective pharmacovigilance program. Although Medwatch, Yellow Card, CDSCO form, etc. are the protocol forms of ADR collection and reports, a number of countries design and use their respective ADR forms. This review compares similarities and dissimilarities of 13 ADR forms of countries representing their geographical location. This study extracted 73 data elements mentioned in 13 different ADR forms. Only 13 elements were common. An ADR form of Malaysia and Canada covers the highest number of data 43, while Brazil falls to the opposite end with a number of 17 data elements in lieu with the Generic ADR Form. The result of this review highlights 58 data elements of the proposed generic ADR form which ensures that requisite reporting information essential for correct causality assessment of ADRs are included. The proposed "Generic ADR form" could be adopted worldwide mandatorily for reporting any/all ADRs associated with marketed drugs.

Fulltext Clinical study of laryngeal cysts

Singh AP, Prasad U

Med J Malaysia, 1982 Sep;37(3):223-6.

PMID: 7177003

This paper describes eight cases of successfully treated laryngeal cysts in different age groups with varying presentation problems.

Fulltext Silicosis among tombstone makers in Malaysia

Jorgensen HS, Singh A

J Occup Med, 1978 Jun;20(6):385, 389, 391.

PMID: 671113

The prevalence of silicosis among Chinese tombstone makers in Malaysia

Singh A, Jorgensen HS

Med J Malaysia, 1978 Jun;32(4):294-6.

PMID: 732625

Fulltext A Comparative Study between Indigenous Low Cost Negative Pressure Wound Therapy with Added Local Oxygen versus Conventional Negative Pressure Wound Therapy

Singh A, Panda K, Mishra J, Dash A

Malays Orthop J, 2020 Nov;14(3):129-136.

PMID: 33403073 DOI: 10.5704/MOJ.2011.020

Introduction: The incidence of compound fractures and severe soft tissue loss has increased manifolds due to high speed traffics. Negative Pressure Wound Therapy (NPWT) is a treatment modality for managing soft tissue aspect of such injuries. It reduces the need of flap coverage. However, many patients from developing countries cannot afford a conventional NPWT. We developed an indigenous low cost NPWT for our patients and supplemented it with Topical Pressurised Oxygen Therapy (TPOT). We conducted this study to compare its treatment outcome with the use of conventional NPWT.

Materials and Methods: The study was conducted from 2018 to 2020 at a tertiary care teaching hospital. A total of 86 patients were treated with NPWT and their results were assessed for various parameters like reduction in wound size, discharge, infection, etc. We included patients with acute traumatic wounds as well as chronic infected wounds, and placed them in three treatment groups to receive either conventional NPWT, Indigenous NPWT and lastly NPWT with supplement TPOT.

Results: We observed a significant reduction of wound size, discharge and infection control in all three groups. The efficacy of indigenous NPWT is at par with conventional NPWT. Only six patients who had several comorbidities required flap coverage while in another four patients we could not achieve desired result due to technical limitations.

Conclusion: Indigenous NPWT with added TPOT is a very potent and cost effective method to control infection and rapid management of severe trauma seen in orthopaedic practice. It also decreases the dependency on plastic surgeons for management of such wounds.

Fulltext Molecular characterization by using 12SrRNA and Cytochrome b for identification of species of genus Ratufa (Rodentia: Scuiridae) including Ratufa indica, endemic species of India

Bahuguna A, Singh A

Mitochondrial DNA B Resour, 2019 Oct 17;4(2):3085-3091.

PMID: 33365866 DOI: 10.1080/23802359.2019.1667270

Oriental giant squirrels are tree squirrels classified under family Ratufinae. In India, there are three species of genus Ratufa, i.e. Ratufa bicolor, Ratufa macroura and Ratufa indica. They are also distributed in South and Southeast Asia. However Ratufa indica is endemic to India. The fourth species Ratufa affinis is restricted to Maritime Southeast Asia (East Malaysia, Indonesia, Brunei and Thailand) and probably in Singapore. The species is near threatened .The species R.macroura is endemic to South Asia. Forests of South and Southeast Asia are hotspots of squirrel diversity but at the same time they are at a high risk of extinction because of high deforestation rate and habitat fragmentation. The present molecular study is the first study of the species of Ratufa for their identification. In this study old taxidermy samples were used for amplification of 12SrRNA and Cytochrome b genes. Maximum likelihood and neighbor-joining methods were used to delineate the species by using MEGA 6 and also for molecular analysis for variable, conserved, parsimony and singleton sites. Similarities between species through BLAST indicated 92.21-89.57% between R.macroura vs. R. bicolour; 93.22-90% Ratufa macroura vs. Ratufa indica; 96-92% Ratufa indica vs. Ratufa bicolour, 93.88% between Ratufa affinis vs. Ratufa indica, 93.5% R. affinis vs. R. bicolor, 90.5%. R. affinis vs. R. macroura. Ratufa bicolor is noted to be genetically closer to R. indica as inferred by using both markers. The BLAST result indicated that the obtained sequences matched 99-100% with their respective species. It was also noted that R. bicolor of Jalpaiguri, West Bengal are genetically closer to that of Bhutan. The study also revealed the evolution of R. indica and R. macroura from a single population.

Fulltext Penerimaan penggunaan mobile learning di kalangan pelajar tingkatan 6 dalam mata pelajaran Geografi

Dympna James Jemson, Sabariah Sharif, Soon Singh A/L Bikar nSingh

Malaysian Journal of Social Sciences and Humanities, 2019;4(6):101-107.

MyJurnal

Kajian ini dilaksanakan untuk melihat penerimaan terhadap penggunaan mobile learning di kalangan pelajar tingkatan 6 dalam mata pelajaran geografi. Kaedah kuantitatif digunakan dalam kajian ini yang melibatkan sebuah pusat tingkatan 6 yang terletak di daerah Kota Kinabalu, Sabah seramai 137 orang pelajar. Semua pelajar yang mengambil mata pelajaran geografi telah diambil sebagai sampel kajian. Borang soal selidik digunakan sebagai instrumen dalam kajian ini yang telah diubahsuai dan dirujuk daripada Technology Acceptance Model (TAM) untuk menentukan tahap penerimaan terhadap penggunaan mobile learning di kalangan pelajar tingkatan 6 dalam mata pelajaran Geografi. Hasil daripada analisis statistik menunjukkan bahawa tahap penerimaan pelajar terhadap mobile learning berada di tahap yang tinggi.

A case report of Blastocystis infection and Steven Johnson's syndrome

Singh A, Priyadarshi K, Raj T, Banerjee T

Trop Biomed, 2019 Dec 01;36(4):987-992.

PMID: 33597468

Blastocystis species (spp.) is an emerging pathogen. There are several unsolved issues linked to this parasite ranging from its nomenclature, commensal status, standardization of laboratory diagnostic methods, genotypes and treatment. Recently, there has been an increase in reports of Blastocystis spp. from symptomatic cases which provide enough evidence of its pathogenic potential. A range of signs and symptoms, from gastro-intestinal to cutaneous manifestations have been attributed to Blastocystis infection. Few reports have established an association between intestinal infection with Blastocystis spp. and skin manifestations in form of urticaria, palmoplantar pruritus and allergy with complete resolution of cutaneous lesions with eradication of the parasite. In this report, we describe a case of Steven Johnson's syndrome (SJS) in a 6 years old girl along with infection with Blastocystis spp. marked by diarrhea and abdominal pain. Stool examination revealed the presence of all forms of the parasite with subsequent decrease in parasite burden and diarrhea over a period of time. Interestingly, the clearance of Blastocystis spp. from stool was followed by recovery from skin lesions and other symptoms. In this case, the course of SJS was clearly associated with Blastocystis infection. Though skin manifestation with Blastocystis infection has been previously reported, this is the first report of its association with SJS. This report indicates newer insights of the parasite that are less well studied.

Survey of medical personnel engaged in occupational health service in West Malaysia

Jorgensen HS, Singh A

Med J Malaysia, 1977 Sep;32(1):28-32.

PMID: 609340

Fulltext Digital lectures for learning gross anatomy: a study of their efficacy

Singh A, Min AK

Korean J Med Educ, 2017 Mar;29(1):27-32.

PMID: 28264551 DOI: 10.3946/kjme.2017.50

PURPOSE: The current study investigates the level of students' learning and attitudes towards the teaching and learning process when using digital lectures to teach gross anatomy to year 1 medical students.

METHODS: The study sampled year 1 medical students of cohorts 2013 and 2014. The year 1 medical students in 2013 were taught gross anatomy of the heart by didactic classroom lectures while those in 2014 were taught with digital lectures using the same content. A review session was conducted for the 2014 cohort. A 19-item survey was distributed amongst students to investigate their attitudes and feedback. The data were analysed using SPSS software.

RESULTS: The 2014 cohort had a mean score of 47.65 for short essay questions and 51.19 for multiple choice questions, while the 2013 cohort scored an average of 36.80 for short essay questions and 49.22 for multiple choice questions. The difference in scores for each type of question was found to be significant. Using a 5-point Likert scale, students gave an average of 4.11 when asked if they liked the teaching and learning process and would like it to be applied further.

CONCLUSION: The results of the study provide strong evidence that the digital teaching and learning process was well received by students and could also lead to improved performance. Digital lectures can provide a satisfactory substitute for classroom lectures to teach gross anatomy, thus providing flexibility in learning and efficient learning, whilst also freeing lecture slots to promote mastery learning.

Simulation-based architecture of a stable large-area [Formula: see text] atmospheric plasma source

Roshan MV, Razaghi S, Singh A

Sci Rep, 2023 Feb 03;13(1):1979.

PMID: 36737465 DOI: 10.1038/s41598-023-29143-5

Unified jet-DBD design, [Formula: see text], proposed in this work presents large-scale plasma in an unbounded region of atmospheric air, without any need for the flow of gas, offering efficient exposure to sizable and complex objects. This is a simulation-based architecture for stable non-thermal plasma source with notable experimental results. [Formula: see text] geometry optimizes the electric field and charge distribution for a diffuse discharge in the steady air by a key design parameter of [Formula: see text]. Teflon insulator with a thickness [Formula: see text] imposes an intense and uniform electric field shaped up at the open area in front of the device and generates radially/axially expanded plasma jet. In the [Formula: see text], phase shift increases by [Formula: see text] and the plasma generates more power than the classical plasma jet. Two distinct states of [Formula: see text] operation indicate the mode-swap at [Formula: see text] and power dissipation. In the reactive [Formula: see text] scheme even small changes in the phase angle effectively improves the electric power.

Fulltext Blast injuries of the ear

Singh AP, Prasad U, Kumar N

Singapore Med J, 1983 Dec;24(6):367-73.

PMID: 6681493

Clinical synopsis and investigations on fourteen patients with blast injuries of the ear successfully treated at the ENT Unit of the University Hospital, Kuala Lumpur, revealed few interesting observations in addition to usual findings. The most outstanding one was the absence of sensorineural deafness, although it has been claimed as one of the most constant features. Conservative management alone was found to be of significant value.

Fulltext The complexity of stromal changes in desmoplastic ameloblastoma

Ramesh V, Singh S, Bailwad S, Kiran K, Agarwal R, Singh A

Ann Med Health Sci Res, 2014 Mar;4(Suppl 1):S14-7.

PMID: 25031898 DOI: 10.4103/2141-9248.131694

Ameloblastoma is usually considered a homogenous neoplasm and is thought of as the most primitive of all odontogenic neoplasms. However, detailed investigations have proven clinicopathological diversity in a significant number of cases, thus mounting the evidence in favor of considering ameloblastoma as a mysterious lesion. The purpose of this article is to report a unique case of desmoplastic ameloblastoma and to throw light on the atypical changes noticed in the stromal component. The findings of this case have served to add interesting parameters to the study of stromal changes associated with this perplexing odontogenic tumor.

Development and characterization of a cell line TTCF from endangered mahseer Tor tor (Ham.)

Yadav K, Lakra WS, Sharma J, Goswami M, Singh A

Fish Physiol Biochem, 2012 Aug;38(4):1035-1045.

PMID: 22203177 DOI: 10.1007/s10695-011-9588-7

Tor tor is an important game and food fish of India with a distribution throughout Asia from the trans-Himalayan region to the Mekong River basin to Malaysia, Pakistan, Bangladesh and Indonesia. A new cell line named TTCF was developed from the caudal fin of T. tor for the first time. The cell line was optimally maintained at 28°C in Leibovitz-15 (L-15) medium supplemented with 20% fetal bovine serum (FBS). The propagation of TTCF cells showed a high plating efficiency of 63.00%. The cytogenetic analysis revealed a diploid count of 100 chromosomes at passage 15, 30, 45 and 60 passages. The viability of the TTCF cell line was found to be 72% after 6 months of cryopreservation in liquid nitrogen (-196°C). The origin of the cell lines was confirmed by the amplification of 578- and 655-bp sequences of 16S rRNA and cytochrome oxidase subunit I (COI) genes of mitochondrial DNA (mtDNA) respectively. TTCF cells were successfully transfected with green fluorescent protein (GFP) reporter plasmids. Further, immunocytochemistry studies confirm its fibroblastic morphology of cells. Genotoxicity assessment of H₂O₂ in TTCF cell line revealed the utility of TTCF cell line as in vitro model for aquatic toxicological studies.

Fulltext Should neonates with specific "risk factors" be admitted to the special care nursery?

Yao SC, Chai MC, Singh A

Med J Malaysia, 1990 Mar;45(1):29-36.

PMID: 2152066

Existing criteria for admission of newborns to the special care nursery, Sarawak General Hospital, resulted in the admission of many neonates with certain risk factors ("at risk" neonates). To test whether such babies could be safely and better cared for in postnatal wards, 392 of these babies were randomly allocated into two groups. One group of 196 was admitted to the special care nursery and the other group of 196 was cared for with their mothers in the postnatal wards. The two groups were compared for mortality, morbidity and breastfeeding. There was no significant difference in mortality and morbidity between the two groups. While in hospital a larger proportion of babies cared for in postnatal wards were breastfed, compared to babies admitted to the special care nursery. In addition, they initiated their breastfeeding earlier. Babies with these risk factors should therefore be cared for with their mothers in the postnatal wards.

"Airplane ear"-A neglected yet preventable problem

Bhattacharya S, Singh A, Marzo RR

AIMS Public Health, 2019;6(3):320-325.

PMID: 31637280 DOI: 10.3934/publichealth.2019.3.320

Delivering emoji/icon-based universal health education messages through smartphones

Bhattacharya S, Singh A, Marzo RR

AIMS Public Health, 2019;6(3):242-247.

PMID: 31637274 DOI: 10.3934/publichealth.2019.3.242

Displaying publications 1 - 20 of 188 in total