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Fulltext Knowledge, attitude, and practice of prophetic food consumption among students of Universiti Sultan Zainal Abidin, Terengganu

Rohin, M. A. K., Sagar, H., Ridzwan, N.

International Food Research Journal, 2020;27(6):1010-1018.
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The present work aimed to investigate the levels of knowledge, attitude, and practice of
prophetic food consumption among UniSZA students. The present work was conducted from
September 2017 until April 2018 at the UniSZA Gong Badak Campus, Terengganu. In this
cross-sectional study, a total of 217 students were recruited by convenience purposive
sampling method. A questionnaire was based on the prophetic food consumption details,
consisting of four sections, namely; demographic data, knowledge, attitude, and practice of
the consumption. Reliability test found that the validity and internal consistency of the
questionnaire to be acceptable with a Cronbach Alpha value of 0.752. Data were analysed
using Microsoft Excel Spreadsheet 2013 and SPSS version 21.0. The results showed that most
of the respondents had good knowledge of prophetic food consumption (45.6%). More than
half had a good level of attitude (66.4%), and only a minority of them (38.2%) had a poor
practice of prophetic food consumption. Based on Independent t-test and One-Way ANOVA
statistical test, there was a significant difference in the mean attitude scores between male and
female students, mean attitude and practice scores between the three age groups, mean
knowledge scores between the three fields of study groups, and mean knowledge, attitude, and
practice scores between the four religions. A positive correlation was observed for the three
domains, namely between knowledge and attitude (r = 0.71), knowledge and practice (ρ =
0.37), and attitude and practice (ρ = 0.43), based on Spearman or Pearson correlation test. In
conclusion, the importance of prophetic food must be highlighted and shared among
multi-religious university students for them to be more familiar with the relevant health and
sustainability issues. The students may employ effective attitude and behaviour towards the
practical implementation of prophetic food if they are provided with more integrated
knowledge in the learning environment of the university.
Fulltext Pomegranate-derived anthocyanin regulates MORs-cAMP/CREB-BDNF pathways in opioid-dependent models and improves cognitive impairments

Ridzwan N, Jumli MN, Baig AA, Rohin MAK

J Ayurveda Integr Med, 2020;11(4):478-488.
PMID: 32430240 DOI: 10.1016/j.jaim.2019.12.001

BACKGROUND: Pomegranate (Punica granatum) is one of the oldest known edible fruit. Recently, there has been an increased interest in this fruit as a functional food for health benefits due to its use in disease prevention and promotion of overall health wellness.
OBJECTIVE: This study aims to investigate the effects of pomegranate extract for the development of non-opioid substitution therapy for in-vitro and in-vivo studies.
MATERIALS AND METHODS: Anthocyanin contents consisting of cyanidin 3-glucoside, diglucoside, and pelargonidin 3-glucoside, diglucoside were detected and quantified in pomegranate extract using high-performance liquid chromatography. The optimum dosage of the extract was determined based on the regulation of MORs and cAMP proteins in U-87 cells. Co-treatment of the extract with morphine was performed to evaluate its potency in reducing the concentration levels of MORs and cAMP. For animal studies, rats were divided into two major groups representing both acute and chronic morphine-induced treatments and the Morris water maze (MWM) study was employed after treatment for each rat. The rats were sacrificed after the treatments and serum samples were collected to evaluate the levels of CREB and BDNF.
RESULTS: The results indicated that each of the anthocyanin content tested in the study was present in the pomegranate extract. Additionally, in-vitro studies using pomegranate extract treatment showed that the extract was effective in decreasing the MORs and cAMP protein levels in U-87 cells at a concentration of 0.125 mg/mL. The memory impairment based on the MWM study in rats was also subsequently improved after treatment with pomegranate extract as compared to treatment with morphine. The blood serum derived from the rats treated with pomegranate extract also showed a significant decrease in CREB level and an increase in BDNF as compared to rats treated with morphine.
CONCLUSION: In conclusion, this study substantiates the potency of pomegranate extract as a non-opioid substitution therapy for in-vitro and in-vivo studies.

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