MyMedR

Displaying all 3 publications

Abstract:

Sort:

Fulltext Neurological infection and complications of SARS-CoV-2: A review

Singh S, Meher N, Mohammed A, Razab MKAA, Bhaskar LVKS, Nawi NM

Medicine (Baltimore), 2023 Feb 03;102(5):e30284.
PMID: 36749239 DOI: 10.1097/MD.0000000000030284

The primary target of severe acute respiratory syndrome coronavirus 2 is the respiratory system including the nose and lungs, however, it can also damage the kidneys, cardiovascular system and gastrointestinal system. Many recent reports suggested that severe acute respiratory syndrome coronavirus 2 infections can also affect the central nervous system as well as peripheral nervous system that lead to the several neurological complications. The virus can break the blood brain barrier and enters the brain via haematological route or directly by the angiotensin-converting enzyme 2 receptors present on endothelial cells of many cerebral tissues. The neurological complications are manifested by headache, dizziness, encephalopathy, encephalitis, cerebrovascular disease, anosmia, hypogeusia, muscle damage, etc. This review article described the possible routes and mechanism of nervous system infection and the range of neurological complications of COVID-19 that may help the medical practitioners and researchers to improve the clinical treatment and reduce the mortality rate among patients with viral diseases.
Fulltext Sono-Chemical Synthesis of Silver Quantum Dots Immobilized on Exfoliated Graphitic Carbon Nitride Nanostructures Using Ginseng Extract for Photocatalytic Hydrogen Evolution, Dye Degradation, and Antimicrobial Studies

Mallikarjuna K, Vattikuti SVP, Manne R, Manjula G, Munirathnam K, Mallapur S, et al.

Nanomaterials (Basel), 2021 Oct 31;11(11).
PMID: 34835682 DOI: 10.3390/nano11112918

Due to modernization and the scarcity of fossil fuel resources, energy demand is continuously increasing. In this regard, it is essential and necessary to create a renewable energy source that can meet future energy demands. Recently, the production of H2 by water splitting and removing pollutants from the water has been essential for issues of energy and environmental demands. Herein, g-C3N4 and Ag-g-C3N4 composite structures have been successfully fabricated by the ultrasonication method. The physio/photochemical properties of prepared g-C3N4 and Ag-g-C3N4 were examined with different analytical techniques such as FTIR, XRD, UV-DRS, SEM, TEM, PL, and XPS analyses. The silver quantum dots (QDS) anchored to g-C3N4 structures performed the profound photocatalytic activities of H2 production, dye degradation, and antimicrobial activity under visible-light irradiation. The Ag/g-C3N4 composite with an Ag loading of 0.02 mole has an optimum photoactivity at 335.40 μmol g-1 h-1, which is superior to other Ag loading g-C3N4 composites. The synthesized Ag/g-C3N4 nanoparticles showed potential microbial inhibition activity during the preliminary screening, and the inhibition zones were comparable to the commercial antibiotic chloramphenicol. The loading of Ag into g-C3N4 paves the suppression, recombination and transfer of photo-generated electron-hole pairs, leading to the enhancement of hydrogen production, the diminishment of pollutants in water under visible light irradiation, and antimicrobial activity against multidrug-resistant pathogens.
Fulltext Correlation between the maximum standard uptake value and mean Hounsfield unit on single-photon emission computed tomography-computed tomography to discriminate benign and metastatic lesions among patients with breast cancer

Saminathan ST, Ahmed WAW, Nawi NM, Tagiling N, Aziz I, Udin Y, et al.

Asian Spine J, 2024 Jun;18(3):398-406.
PMID: 38917860 DOI: 10.31616/asj.2022.0451

STUDY DESIGN: Retrospective study.
PURPOSE: To compare and correlate technetium-99m methylene diphosphonate uptake between benign and metastatic bone lesions using semiquantitative analysis of maximum standard uptake value (SUVmax) and mean Hounsfield unit (HU) in single-photon emission computed tomography-computed tomography (SPECT-CT).
OVERVIEW OF LITERATURE: Qualitative interpretation of metastatic bone lesions in breast cancer on bone scintigraphy is often complicated by coexisting benign lesions.
METHODS: In total, 185 lesions were identified on bone and SPECT-CT scans from 32 patients. Lesions were classified as metastatic (109 sclerotic lesions) and benign (76 lesions) morphologically on low-dose CT. Semiquantitative analysis using SUVmax and mean HU was performed on the lesions and compared. To discriminate benign and metastatic lesions, the correlation between SUVmax and mean HU was determined using the intraclass correlation coefficients.
RESULTS: The SUVmax was higher in metastatic lesions (20.66±14.36) but lower in benign lesions (10.18±12.79) (p<0.001). The mean HU was lower in metastatic lesions (166.62±202.02) but higher in benign lesions (517.65±192.8) (p<0.001). A weak negative correlation was found between the SUVmax and the mean HU for benign lesions, and a weak positive correlation was noted between the SUVmax and the mean HU on malignant lesions with no statistical significance (p=0.394 and 0.312, respectively). The cutoff values obtained were 10.8 for SUVmax (82.6% sensitivity and 84.2% specificity) and 240.86 for the mean HU (98.7% sensitivity and 88.1% specificity) in differentiating benign from malignant bone lesions.
CONCLUSIONS: Semiquantitative assessment using SUVmax and HU can complement qualitative analysis. Metastatic lesions had higher SUVmax but lower mean HU than benign lesions, whereas benign lesions demonstrated higher mean HU but lower SUVmax. A weak correlation was found between the SUVmax and the mean HU on malignant and benign lesions. Cutoff values of 10.8 for the SUVmax and 240.86 for the mean HU may differentiate bone metastases from benign lesions.

Filters

Please provide feedback to Administrator ([email protected])

External Links